Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Frédéric Eeckman"'
Autor:
Pierre-François Chavez, Fanny Stauffer, Frédéric Eeckman, Nils Bostijn, David Didion, Cédric Schaefer, Hong Yang, Yousef El Aalamat, Xavier Lories, Martin Warman, Benoit Mathieu, Jérôme Mantanus
Publikováno v:
International journal of pharmaceutics. 624
This paper describes the specific control strategy of the commercial manufacturing process of an immediate release tablet formulation based on continuous twin-screw wet granulation. This control strategy has been defined by a multidisciplinary team u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cb3a4a06f96e2e2f4841c11442493ad
https://pubmed.ncbi.nlm.nih.gov/35781027
https://pubmed.ncbi.nlm.nih.gov/35781027
Autor:
Anne Otto, Frédéric Eeckman, David Fontaine, Hugues Malonne, André Jules Moes, Louis De Vos, Jeanine Fontaine, Karim Amighi
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 61:188-194
A subacute toxicity study was conducted to evaluate the oral toxicity profile of poly(N-isopropylacrylamide) (PNIPAAm) derivatives. These thermoresponsive polymers may have several potential pharmaceutical applications such as ingredient for oral sol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d7b5e1778f0a1d1e2923870e2fdac8f
https://doi.org/10.1016/j.ejpb.2005.05.007
https://doi.org/10.1016/j.ejpb.2005.05.007
Publikováno v:
European Polymer Journal. 40:873-881
Poly(N-isopropylacrylamide) (PNIPAAm) copolymers were synthesized in order to obtain co-polymers with a phase transition temperature slightly higher than the physiological temperature, as required by a new drug delivery concept described in a previou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c2c7a0dc3b11af79ca9b70091cdcfdd
https://doi.org/10.1016/j.eurpolymj.2003.11.010
https://doi.org/10.1016/j.eurpolymj.2003.11.010
Publikováno v:
International Journal of Pharmaceutics. 241:113-125
The purpose of this work is to develop a new delivery concept making a thermosensitive polymer based on poly(N-isopropylacrylamide) (PNIPAAm) useful as a time-controlled drug release device, without any temperature changes of the dissolution medium.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8fd74886bea741ff84c6e8701b3e8b5
https://doi.org/10.1016/s0378-5173(02)00198-9
https://doi.org/10.1016/s0378-5173(02)00198-9
Publikováno v:
International Journal of Pharmaceutics. 222:259-270
Poly-N-isopropylacrylamide (PNIPAAm) thermosensibility makes this polymer a very attractive candidate for controlled drug delivery systems. The polymer possesses a lower critical solution temperature (LCST) which was found to be around 32 degrees C i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c2749a26287e9b674c1702982f8eb13
https://doi.org/10.1016/s0378-5173(01)00716-5
https://doi.org/10.1016/s0378-5173(01)00716-5
Publikováno v:
International journal of pharmaceutics. 273(1-2)
In the course of the development of a new drug delivery concept, four thermosensitive copolymers of poly(N-isopropylacrylamide) (PNIPAAm), with phase transition temperature slightly higher than 37 degrees C, were synthesised and used as time-controll
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4fb821e4b5b0fd1f560595cc513dc8f
https://pubmed.ncbi.nlm.nih.gov/15010135
https://pubmed.ncbi.nlm.nih.gov/15010135
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 88(1)
A novel approach of controlled drug delivery using thermosensitive polymers is developed in this paper. The drug release occurs at physiological temperature, at which the polymer is normally not soluble, and no medium temperature changes are required
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::480b70ed356cd0518716b4f82d4718e7
https://pubmed.ncbi.nlm.nih.gov/12586508
https://pubmed.ncbi.nlm.nih.gov/12586508