α6 Integrin (α6high)/Transferrin Receptor (CD71)low Keratinocyte Stem Cells Are More Potent for Generating Reconstructed Skin Epidermis Than Rapid Adherent Cells

Autor: Elodie Metral, Nicolas Bechetoille, Frédéric Demarne, Walid Rachidi, Odile Damour

Publikováno v: International Journal of Molecular Sciences, Vol 18, Iss 2, p 282 (2017)

The epidermis basal layer is composed of two keratinocyte populations: Keratinocyte Stem cells (KSC) and Transitory Amplifying (TA) cells that arise from KSC division. Unfortunately, no specific marker exists to differ between KSC and TA cells. Here,

Externí odkaz: https://doaj.org/article/bda7432cdb094d48966e6855206db56f

Mitochondrial damage and cytoskeleton reorganization in human dermal fibroblasts exposed to artificial visible light similar to screen-emitted light

Autor: Adeline Rascalou, Nicolas Bechetoille, Frédéric Demarne, Pauline Poydenot, Jérôme Lamartine

Publikováno v: Journal of Dermatological Science. 91:195-205

Background Artificial visible light is everywhere in modern life. Social communication confronts us with screens of all kinds, and their use is on the rise. We are therefore increasingly exposed to artificial visible light, the effects of which on sk

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b073a5428ae6d833cb0bc1275e8a72e
https://doi.org/10.1016/j.jdermsci.2018.04.018

In-vitro investigation regarding the effects of Gelucire ® 44/14 and Labrasol® ALF on the secretory intestinal transport of P-gp substrates

Autor: Océane Dubray, Yann Pellequer, Alf Lamprecht, Frédéric Demarne, Vincent Jannin, Arnaud Béduneau

Publikováno v: International Journal of Pharmaceutics. 515:293-299

In this present study, the secretory transport of P-gp substrates, rhodamine 123 and digoxin, was evaluated using a Caco-2/HT29-MTX co-culture characterized by an efflux mechanism and a paracellular permeability closer to the human intestinal barrier

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d27b1260859ba5bbf8057ebfaddc77e7
https://doi.org/10.1016/j.ijpharm.2016.10.012

Keratinocyte stem cells are more resistant to UVA radiation than their direct progeny

Autor: Nicolas Bechetoille, Frédéric Demarne, Walid Rachidi, Elodie Metral, Odile Damour

Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2018, 13 (9), pp.e0203863
PLoS ONE, Vol 13, Iss 9, p e0203863 (2018)
PLoS ONE, 2018, 13 (9), pp.e0203863

The epidermis undergoes constant renewal during its lifetime. This is possible due to a special population of keratinocyte stem cells (KSCs) located at the basal layer. These cells are surrounded by their direct progeny, keratinocyte progenitors or t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d579e97c855def8802b2d90b94ba4f7b
https://hal.archives-ouvertes.fr/hal-02013099

Size characterization of commercial micelles and microemulsions by Taylor dispersion analysis

Autor: Florian Davanier, Joseph Chamieh, Vincent Jannin, Hervé Cottet, Frédéric Demarne

Publikováno v: International Journal of Pharmaceutics. 492:46-54

In this work, Taylor dispersion analysis was applied to the measurement of micelles (or microdroplets) molecular diffusion coefficient in micellar (or microemulsion) systems based on neutral/anionic/cationic or zwitterionic surfactants. The choice of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4958c1cbeb2a6f646720cc881ac27407
https://doi.org/10.1016/j.ijpharm.2015.06.037