Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Frédéric Clotman"'
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
Amyotrophic lateral sclerosis (ALS) consists of a group of adult-onset fatal and incurable neurodegenerative disorders characterized by the progressive death of motor neurons (MNs) throughout the central nervous system (CNS). At first, ALS was consid
Externí odkaz:
https://doaj.org/article/64892792f71349959e74551959071cf8
Autor:
Ana Dominguez-Bajo, Frédéric Clotman
Publikováno v:
Cells, Vol 13, Iss 8, p 652 (2024)
The differential expression of transcription factors during embryonic development has been selected as the main feature to define the specific subclasses of spinal interneurons. However, recent studies based on single-cell RNA sequencing and transcri
Externí odkaz:
https://doaj.org/article/16391dd122bc43f99a451ed2c46d5483
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S678- (2023)
Externí odkaz:
https://doaj.org/article/4b122f8d57dc4829a83d712c4cd5a66f
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-20 (2020)
Abstract Genetic and epigenetic factors contribute to the development of the spinal cord. Failure in correct exertion of the developmental programs, including neurulation, neural tube closure and neurogenesis of the diverse spinal cord neuronal subty
Externí odkaz:
https://doaj.org/article/55b05efba07448b79c00a50ab7b24b68
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Spinal dorsal interneurons, which are generated during embryonic development, relay and process sensory inputs from the periphery to the central nervous system. Proper integration of these cells into neuronal circuitry depends on their correct positi
Externí odkaz:
https://doaj.org/article/29bdd193f51a4fb8ada53a4ead2fdd3a
Autor:
Audrey Harris, Gauhar Masgutova, Amandine Collin, Mathilde Toch, Maria Hidalgo-Figueroa, Benvenuto Jacob, Lynn M. Corcoran, Cédric Francius, Frédéric Clotman
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Acquisition of proper neuronal identity and position is critical for the formation of neural circuits. In the embryonic spinal cord, cardinal populations of interneurons diversify into specialized subsets and migrate to defined locations within the s
Externí odkaz:
https://doaj.org/article/c825144bd1d244c2bf42041fdbd893c8
Autor:
Karolina U. Kabayiza, Gauhar Masgutova, Audrey Harris, Vincent Rucchin, Benvenuto Jacob, Frédéric Clotman
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
During embryonic development, the dorsal spinal cord generates numerous interneuron populations eventually involved in motor circuits or in sensory networks that integrate and transmit sensory inputs from the periphery. The molecular mechanisms that
Externí odkaz:
https://doaj.org/article/177142f4917348f6850713908df49ac6
Autor:
Koushik Chakrabarty, Lars Von Oerthel, Anita Hellemons, Frédéric Clotman, Agnès Espana, Marian Groot Koerkamp, Frank C. P. Holstege, R. Jeroen Pasterkamp, Marten P. Smidt
Publikováno v:
Biology Open, Vol 1, Iss 8, Pp 693-704 (2012)
Summary Meso-diencephalic dopaminergic (mdDA) neurons are critical for motor control and cognitive functioning and their loss or dysfunction is associated with disorders such as Parkinson's disease (PD), schizophrenia and addiction. However, relative
Externí odkaz:
https://doaj.org/article/3658d337605c45718fdc0ad2ef0397e5
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142280 (2015)
Thioredoxin-2 (Trx2) is a mitochondrial protein using a dithiol active site to reduce protein disulfides. In addition to the cytoprotective function of this enzyme, several studies have highlighted the implication of Trx2 in cellular signaling events
Externí odkaz:
https://doaj.org/article/1088819dac4f4eea9766e9c3c4922e55
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71320 (2013)
Type-I interferons (IFNs) form a large family of cytokines that primarily act to control the early development of viral infections. Typical type-I IFN genes, such as those encoding IFN-α or IFN-β are upregulated by viral infection in many cell type
Externí odkaz:
https://doaj.org/article/7a07331da00f42168439a002f4048f0d