Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Frédéric A Meunier"'
Publikováno v:
eLife, Vol 13 (2024)
Protein kinases (PKs) are proteins at the core of cellular signalling and are thereby responsible for most cellular physiological processes and their regulations. As for all intracellular proteins, PKs are subjected to Brownian thermal energy that te
Externí odkaz:
https://doaj.org/article/946849513629425ba8284ea3ddd1d34e
Autor:
Yanshan Zhu, Keng Yih Chew, Melanie Wu, Anjana C Karawita, Georgina McCallum, Lauren E Steele, Ayaho Yamamoto, Larisa I Labzin, Tejasri Yarlagadda, Alexander A Khromykh, Xiaohui Wang, Julian D J Sng, Claudia J Stocks, Yao Xia, Tobias R Kollmann, David Martino, Merja Joensuu, Frédéric A Meunier, Giuseppe Balistreri, Helle Bielefeldt-Ohmann, Asha C Bowen, Anthony Kicic, Peter D Sly, Kirsten M Spann, Kirsty R Short
Publikováno v:
PLoS Biology, Vol 20, Iss 8, p e3001728 (2022)
Children typically experience more mild symptoms of Coronavirus Disease 2019 (COVID-19) when compared to adults. There is a strong body of evidence that children are also less susceptible to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2
Externí odkaz:
https://doaj.org/article/a26c38131664476296b2cb3b91aefadf
Publikováno v:
eLife, Vol 8 (2019)
The Src kinase Fyn plays critical roles in memory formation and Alzheimer’s disease. Its targeting to neuronal dendrites is regulated by Tau via an unknown mechanism. As nanoclustering is essential for efficient signaling, we used single-molecule t
Externí odkaz:
https://doaj.org/article/31bf7e62daee4bd1994b22b335b4fbac
Autor:
Adekunle T. Bademosi, Elsa Lauwers, Pranesh Padmanabhan, Lorenzo Odierna, Ye Jin Chai, Andreas Papadopulos, Geoffrey J. Goodhill, Patrik Verstreken, Bruno van Swinderen, Frédéric A Meunier
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-1 (2017)
Nature Communications 7: Article number: 13660 (2016); Published: 16 December 2016; Updated: 9 February 2017 This Article was originally published with an incorrect publication date. The paper was due to be published on 3 Jan 2017, but due to an erro
Externí odkaz:
https://doaj.org/article/e0a23471e1714e08a79e6ba4c013b750
Autor:
César Mattei, Peter J Wen, Truong D Nguyen-Huu, Martha Alvarez, Evelyne Benoit, Andrea J Bourdelais, Richard J Lewis, Daniel G Baden, Jordi Molgó, Frédéric A Meunier
Publikováno v:
PLoS ONE, Vol 3, Iss 10, p e3448 (2008)
Ciguatoxins and brevetoxins are neurotoxic cyclic polyether compounds produced by dinoflagellates, which are responsible for ciguatera and neurotoxic shellfish poisoning (NSP) respectively. Recently, brevenal, a natural compound was found to specific
Externí odkaz:
https://doaj.org/article/c082801b106145febe09f57e4970a7bd
Autor:
Ramón Martínez-Mármol, Christopher Small, Anmin Jiang, Tishila Palliyaguru, Tristan P. Wallis, Rachel S. Gormal, Jean-Baptiste Sibarita, Jürgen Götz, Frédéric A. Meunier
Publikováno v:
Molecular Psychiatry. 28:946-962
Fyn is a Src kinase that controls critical signalling cascades and has been implicated in learning and memory. Postsynaptic enrichment of Fyn underpins synaptotoxicity in dementias such as Alzheimer’s disease and frontotemporal lobar degeneration w
Autor:
Merja Joensuu, Parnayan Syed, Saber H Saber, Vanessa Lanoue, Tristan P Wallis, James Rae, Ailisa Blum, Rachel S Gormal, Christopher Small, Shanley Sanders, Anmin Jiang, Stefan Mahrhold, Nadja Krez, Michael A Cousin, Ruby Cooper‐White, Justin J Cooper‐White, Brett M Collins, Robert G Parton, Giuseppe Balistreri, Andreas Rummel, Frédéric A Meunier
Publikováno v:
Joensuu, M, Syed, P, Saber, S H, Lanoue, V, Wallis, T P, Rae, J, Blum, A, Gormal, R S, Small, C, Sanders, S, Jiang, A, Mahrhold, S, Krez, N, Cousin, M A, Cooper-White, R, Cooper-White, J J, Collins, B M, Parton, R G, Balistreri, G, Rummel, A & Meunier, F A 2023, ' Presynaptic targeting of botulinum neurotoxin type A requires a tripartite PSG-Syt1-SV2 plasma membrane nanocluster for synaptic vesicle entry ', EMBO Journal . https://doi.org/10.15252/embj.2022112095
The unique nerve terminal targeting of botulinum neurotoxin type A (BoNT/A) is due to its capacity to bind two receptors on the neuronal plasma membrane: polysialoganglioside (PSG) and synaptic vesicle glycoprotein 2 (SV2). Whether and how PSGs and S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bce58369df1764dd9ade86c6d436254
https://hdl.handle.net/20.500.11820/ba1259b2-1e41-40ca-b588-79326111cfdd
https://hdl.handle.net/20.500.11820/ba1259b2-1e41-40ca-b588-79326111cfdd
Autor:
Isaac O. Akefe, Benjamin Matthews, Saber H. Saber, Bharat G. Venkatesh, Rachel S. Gormal, Daniel G. Blackmore, Emma Sieriecki, Yann Gambin, Jesus Bertran-Gonzalez, Alysee A. Michaels, Mingshan Xue, Benjamin Cravatt, Merja Joensuu, Tristan P. Wallis, Frédéric A. Meunier
The phospholipid and free fatty acid (FFA) composition of neuronal membranes plays a crucial role in learning and memory, but the mechanisms through which neuronal activity affects the brain’s lipid landscape remain largely unexplored. Saturated FF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::369589b388e226078a95eb95f849cf10
https://doi.org/10.1101/2023.05.11.540316
https://doi.org/10.1101/2023.05.11.540316
Autor:
Ramón Martínez‐Mármol, YeJin Chai, Jacinta N. Conroy, Zahra Khan, Seong‐Min Hong, Seon Beom Kim, Rachel S. Gormal, Dae Hee Lee, Jae Kang Lee, Elizabeth J. Coulson, Mi Kyeong Lee, Sun Yeou Kim, Frédéric A. Meunier
Publikováno v:
Journal of Neurochemistry.
Autor:
Romal Stewart, Sevannah A. Ellis, Kexin Yan, Troy Dumenil, Bing Tang, Wilson Nguyen, Cameron Bishop, Thibaut Larcher, Rhys Parry, Robert K. P. Sullivan, Mary Lor, Alexander A. Khromykh, Frédéric A. Meunier, Daniel J. Rawle, Andreas Suhrbier
A frequently repeated premise is that viruses evolve to become less pathogenic. This appears also to be true for SARS-CoV-2, although the increased level of immunity in human populations makes it difficult to distinguish between reduced intrinsic pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce0bce341bb24be0ded78541f6230863
https://doi.org/10.1101/2022.12.22.521696
https://doi.org/10.1101/2022.12.22.521696