Arf6 is necessary for senseless expression in response to wingless signalling during Drosophila wing development

Autor: Julien Marcetteau, Tamàs Matusek, Frédéric Luton, Pascal P. Thérond

Publikováno v: Biology Open, Vol 10, Iss 12 (2021)

Wnt signalling is a core pathway involved in a wide range of developmental processes throughout the metazoa. In vitro studies have suggested that the small GTP binding protein Arf6 regulates upstream steps of Wnt transduction, by promoting the phosph

Externí odkaz: https://doaj.org/article/da0b5f7e736e4c70a68c42cf92007274

Chlortetracycline, a Novel Arf Inhibitor That Decreases the Arf6-Dependent Invasive Properties of Breast Cancer Cells

Autor: Eric Macia, Monserrat Vazquez-Rojas, Alessia Robiolo, Racha Fayad, Sophie Abélanet, Isabelle Mus-Veteau, Fabien Fontaine-Vive, Mohamed Mehiri, Frédéric Luton, Michel Franco

Publikováno v: Molecules, Vol 26, Iss 4, p 969 (2021)

Breast cancer is a major disease for women worldwide, where mortality is associated with tumour cell dissemination to distant organs. While the number of efficient anticancer therapies increased in the past 20 years, treatments targeting the invasive

Externí odkaz: https://doaj.org/article/e4d3d005e5dc453380a0885aa347ff2e

Arf6 is necessary for senseless expression in response to wingless signalling during Drosophila wing development

Autor: Pascal P. Thérond, Julien Marcetteau, Tamás Matusek, Frédéric Luton

Publikováno v: Biology Open
article-version (VoR) Version of Record
Biology Open, Vol 10, Iss 12 (2021)

Wnt signalling is a core pathway involved in a wide range of developmental processes throughout the metazoa. In vitro studies have suggested that the small GTP binding protein Arf6 regulates upstream steps of Wnt transduction, by promoting the phosph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c022ce6a3b72490b4815c85af8ea70a9
https://pubmed.ncbi.nlm.nih.gov/34779478

EFA6B regulates a stop signal for collective invasion in breast cancer

Autor: Shiraz Dib, Mariagrazia Partisani, Pascal Finetti, Virginie Virolle, Anne Farina, Frédéric Luton, Marc Lopez, Michel Franco, Sophie Abelanet, Monserrat Vázquez Rojas, Olivier Cabaud, Racha Fayad, Daniel Birnbaum, François Bertucci

Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12, pp.2198. ⟨10.1038/s41467-021-22522-4⟩
Nature Communications, 2021, 12, pp.2198. ⟨10.1038/s41467-021-22522-4⟩
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)

Cancer is initiated by somatic mutations in oncogenes or tumor suppressor genes. However, additional alterations provide selective advantages to the tumor cells to resist treatment and develop metastases. Their identification is of paramount importan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0472ce9944e8675ae9b1cd7dcf7bf89c
http://europepmc.org/articles/PMC8044243

EFA6A, an exchange factor for Arf6, regulates early steps in ciliogenesis

Autor: Sophie Pagnotta, Carole Baron, Rania Ghossoub, Eric Macia, Sophie Abelanet, Mariagrazia Partisani, Alexandre Benmerah, Sandra Lacas-Gervais, Frédéric Luton, Michel Franco, Racha Fayad, Frédéric Brau

Publikováno v: Journal of Cell Science
Journal of Cell Science, Company of Biologists, 2021, 134 (2), pp.jcs249565. ⟨10.1242/jcs.249565⟩
Journal of Cell Science, Company of Biologists, 2021, 134 (2), ⟨10.1242/jcs.249565⟩
Journal of Cell Science, 2021, 134 (2), ⟨10.1242/jcs.249565⟩

Ciliogenesis is a coordinated process initiated by the recruitment and fusion of pre-ciliary vesicles at the distal appendages of the mother centriole through mechanisms that remain unclear. Here, we report that EFA6A (also known as PSD), an exchange

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c44b933125448566811cefbee51fe3ba
https://hal.archives-ouvertes.fr/hal-03120586/document