Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Frédéric, Labéguère"'
Autor:
Stéphanie Lavazais, Manja Jargosch, Sonia Dupont, Frédéric Labéguère, Christel Menet, Catherine Jagerschmidt, Frenz Ohm, Laszlo Kupcsik, Isabelle Parent, Céline Cottereaux, Florence Marsais, Line Oste, An Van de Water, Thierry Christophe, Steve De Vos, Padraic Fallon, Felix Lauffer, Philippe Clément-Lacroix, Kilian Eyerich, Reginald Brys
Publikováno v:
Science Translational Medicine. 15
Innate immunity not only shapes the way epithelial barriers interpret environmental cues but also drives adaptive responses. Therefore, modulators of innate immune responses are expected to have high therapeutic potential across immune-mediated infla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d1ddc3b64e21e46fda5864368a152e3
https://doi.org/10.1126/scitranslmed.abj3289
https://doi.org/10.1126/scitranslmed.abj3289
Autor:
Frédéric, Labéguère, Sonia, Dupont, Luke, Alvey, Florilène, Soulas, Gregory, Newsome, Amynata, Tirera, Vanessa, Quenehen, Thi Thu Trang, Mai, Pierre, Deprez, Roland, Blanqué, Line, Oste, Sandrine, Le Tallec, Steve, De Vos, Annick, Hagers, Ann, Vandevelde, Luc, Nelles, Nele, Vandervoort, Katja, Conrath, Thierry, Christophe, Ellen, van der Aar, Emanuelle, Wakselman, Didier, Merciris, Céline, Cottereaux, Cécile, da Costa, Laurent, Saniere, Philippe, Clement-Lacroix, Laura, Jenkins, Graeme, Milligan, Stephen, Fletcher, Reginald, Brys, Romain, Gosmini
Publikováno v:
Journal of medicinal chemistry. 63(22)
GPR84 is a medium chain free fatty acid-binding G-protein-coupled receptor associated with inflammatory and fibrotic diseases. As the only reported antagonist of GPR84 (PBI-4050) that displays relatively low potency and selectivity, a clear need exis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dca817b6050468a00027ab8ce9b149c4
https://pubmed.ncbi.nlm.nih.gov/32902984
https://pubmed.ncbi.nlm.nih.gov/32902984
Publikováno v:
Synthetic Communications. 42:1461-1471
Two unreported C-glycosylated amino acid structures could be prepared by addition of an amino acid organozinc on carbohydrates bearing an aldehyde function. For this purpose, a new iodinated amino acid bearing a four-carbon side chain was convenientl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6737afc73227f4b1393e629d3964e7cf
https://doi.org/10.1080/00397911.2010.540698
https://doi.org/10.1080/00397911.2010.540698
Publikováno v:
European Journal of Organic Chemistry. 2000:3755-3761
4-Amino-3-(aminomethyl)benzoic acid (1) (AmAbz) is a novel unnatural amino acid with promise in applications as a building block for the synthesis of peptidomimetics and as a scaffold for combinatorial chemistry. It was efficiently synthesized in thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28fa4c598f9a7bb4b2df4abe756de2f6
https://doi.org/10.1002/1099-0690(200011)2000:22<3755::aid-ejoc3755>3.0.co
https://doi.org/10.1002/1099-0690(200011)2000:22<3755::aid-ejoc3755>3.0.co
Publikováno v:
ChemInform. 43
A protocol for the Lewis acid mediated addition of the new amino acid organozinc compound (VI) to simple aldehydes is developed and successfully applied to the synthesis of novel C-glycosylated amino acids such as (X).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce0454395aa6d52d0243b20c1975fd2c
https://doi.org/10.1002/chin.201238200
https://doi.org/10.1002/chin.201238200
Publikováno v:
Tetrahedron Letters. 43:7271-7272
A diastereoselective synthesis of β-1-formyl-2,3,4,6-tetra-O-benzyl- d -glucopyranoside in four steps, using an umpolung Seebach reaction is described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::521dbb36ef897420a5dbc00238657cff
https://doi.org/10.1016/s0040-4039(02)01477-6
https://doi.org/10.1016/s0040-4039(02)01477-6