Výsledky vyhledávání - "Frédéric, Bérenguer"

Urine proteomic profiling of uranium nephrotoxicity

Autor: Eric Quéméneur, Véronique Malard, Jean-Charles Gaillard, Frédéric Bérenguer, Nicole Sage

Publikováno v: Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1794:882-891

Uranium is used in many chemical forms in civilian and military industries and is a known nephrotoxicant. A key issue in monitoring occupational exposure is to be able to evaluate the potential damage to the body, particularly the kidney. In this stu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::315eeb7fd6373724ea8715e30722ec77
https://doi.org/10.1016/j.bbapap.2009.01.010

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Proteomic analysis of the response of human lung cells to uranium

Autor: Elisabeth Darrouzet, Eric Quéméneur, Nicole Sage, Frédéric Bérenguer, Véronique Malard, Odette Prat

Publikováno v: PROTEOMICS. 5:4568-4580

The industrial use of uranium and particularly of depleted uranium, has pinpointed the need to review its chemical impact on human health. A proteomic approach was used to evaluate the response of a human lung cell line (A549) to uranium. We establis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbfe144ae5bd178da09181fa052037e4
https://doi.org/10.1002/pmic.200402038

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Toxicity evaluation of manufactured CeO2 nanoparticles before and after alteration: combined physicochemical and whole-genome expression analysis in Caco-2 cells

Autor: Matthieu Fisichella, Mélanie Auffan, Gérard Steinmetz, Jérôme Rose, Odette Prat, Frédéric Bérenguer

Publikováno v: BMC Genomics
BMC Genomics, BioMed Central, 2014, 15, ⟨10.1186/1471-2164-15-700⟩
BMC Genomics, 2014, 15, ⟨10.1186/1471-2164-15-700⟩

Background Engineered nanomaterials may release nanosized residues, by degradation, throughout their life cycle. These residues may be a threat for living organisms. They may be ingested by humans through food and water. Although the toxicity of pris

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2889e1432ca4f2879d69a051e78c07b
https://hal.archives-ouvertes.fr/hal-01426112

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Intestinal toxicity evaluation of TiO2 degraded surface-treated nanoparticles: a combined physico-chemical and toxicogenomics approach in caco-2 cells

Autor: Frédéric Bérenguer, Mélanie Auffan, Gérard Steinmetz, Matthieu Fisichella, Jérôme Rose, Odette Prat

Publikováno v: Particle and Fibre Toxicology
Particle and Fibre Toxicology, BioMed Central, 2012, 9, ⟨10.1186/1743-8977-9-18⟩
Particle and Fibre Toxicology, Vol 9, Iss 1, p 18 (2012)
Particle and Fibre Toxicology, 2012, 9, ⟨10.1186/1743-8977-9-18⟩

Background Titanium dioxide (TiO2) nanoparticles (NPs) are widely used due to their specific properties, like UV filters in sunscreen. In that particular case TiO2 NPs are surface modified to avoid photocatalytic effects. These surface-treated nanopa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82ba99842025d15c925297a3a91cb4c5
https://hal.archives-ouvertes.fr/hal-01426198

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Alterations in gene expression in cultured human cells after acute exposure to uranium salt: Involvement of a mineralization regulator

Autor: Eric Quéméneur, Nicole Sage, Sylvie Ruat, Odette Prat, Gérard Steinmetz, Frédéric Bérenguer

Publikováno v: Toxicology in vitro : an international journal published in association with BIBRA. 24(1)

The risk of exposure of workers or populations to materials, such as uranium, of nuclear fuel process origins is a major concern worldwide. Our goal is to improve the knowledge of mechanisms ruling its chemical toxicity, and to search for proteins as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb1ef1d7470db387fd4b510e0b0d5acb
https://pubmed.ncbi.nlm.nih.gov/19654044

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Boundaries and physical characterization of a new domain shared between mammalian 53BP1 and yeast Rad9 checkpoint proteins

Autor: Eric Quéméneur, Sophie Zinn-Justin, Gaëlle Charier, Frédéric Bérenguer, Nathalie Nozerand, Alain Lorphelin, Bernard Gilquin, Joël Couprie, Béatrice Alpha-Bazin, Charles Marchetti

Publikováno v: Protein science : a publication of the Protein Society. 14(7)

Eukaryotic cells have evolved DNA damage checkpoints in response to genome damage. They delay the cell cycle and activate repair mechanisms. The kinases at the heart of these pathways and the accessory proteins, which localize to DNA lesions and regu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e47edd9d44e783a619481be5e037e74d
https://pubmed.ncbi.nlm.nih.gov/15987907

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Transcriptomic and proteomic responses of human renal HEK293 cells to uranium toxicity

Autor: Nicole Sage, Emmanuelle Tavan, Frédéric Bérenguer, Gérard Steinmetz, Odette Prat, Eric Quéméneur, Véronique Malard

Publikováno v: Proteomics. 5(1)

The industrial use of uranium, in particular depleted uranium, has pin-pointed the need to review its chemical impact on human health. Global methodologies, applied to the field of toxicology, have demonstrated their applicability to investigation of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcbf45ff743c3b62253243c09324b655
https://pubmed.ncbi.nlm.nih.gov/15672453

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