Pharmacological inhibition of myostatin improves skeletal muscle mass and function in a mouse model of stroke

Autor: Marine Maud Desgeorges, Xavier Devillard, Jérome Toutain, Josiane Castells, Didier Divoux, David Frédéric Arnould, Christopher Haqq, Myriam Bernaudin, Anne-Cécile Durieux, Omar Touzani, Damien Gilles Freyssenet

Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)

Abstract In stroke patients, loss of skeletal muscle mass leads to prolonged weakness and less efficient rehabilitation. We previously showed that expression of myostatin, a master negative regulator of skeletal muscle mass, was strongly increased in

Externí odkaz: https://doaj.org/article/ad0c911773f74bc491f220592714b3a1

Pharmacological inhibition of myostatin improves skeletal muscle mass and function in a mouse model of stroke

Autor: Josiane Castells, Marine Maud Desgeorges, Damien Freyssenet, Christopher Haqq, Omar Touzani, David Frédéric Arnould, Myriam Bernaudin, Anne-Cécile Durieux, Didier Divoux, Xavier Devillard, Jérôme Toutain

Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports
Scientific Reports, 2017, 7 (1), pp.14000. ⟨10.1038/s41598-017-13912-0⟩
Scientific Reports, Nature Publishing Group, 2017, 7 (1), pp.14000. ⟨10.1038/s41598-017-13912-0⟩

In stroke patients, loss of skeletal muscle mass leads to prolonged weakness and less efficient rehabilitation. We previously showed that expression of myostatin, a master negative regulator of skeletal muscle mass, was strongly increased in skeletal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e664be5f2fe3aab7a539b84f0b6ca0a5
https://doi.org/10.1038/s41598-017-13912-0