Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Frédéric, Alby"'
Autor:
Clara Salazar-Cardozo, Véronique Masson, Paola B. Arimondo, Frédéric Alby, Laurence Fleury, Jean-Marc Gregoire, Frédéric Ausseil
Publikováno v:
BMC Cancer
BMC Cancer, BioMed Central, 2016, 16 (1), pp.700. ⟨10.1186/s12885-016-2683-5⟩
BMC Cancer, BioMed Central, 2016, 16 (1), pp.700. ⟨10.1186/s12885-016-2683-5⟩
Background In breast cancer, the epithelial to mesenchyme transition (EMT) is associated to tumour dissemination, drug resistance and high relapse risks. It is partly controlled by epigenetic modifications such as histone acetylation and methylation.
Autor:
Etienne Decroly, Nils Marechal, Jean Cavarelli, V. Cura, Céline Faux, L. Bonnefond, Dominique Guianvarc'h, Frédéric Alby, Patrick Page, Paola B. Arimondo, Ludovic Halby, Jean-Claude Guillemot, Nathalie Troffer-Charlier, Don-Marc Franchini, Srikanth Kudithipudi, Clotilde Ferroud, Dany Pechalrieu, Wahiba Aouadi, Albert Jeltsch
Publikováno v:
Philosophical Transactions of the Royal Society B: Biological Sciences
Philosophical Transactions of the Royal Society B: Biological Sciences, Royal Society, The, 2018, 373 (1748), pp.20170072. ⟨10.1098/rstb.2017.0072⟩
Philosophical Transactions of the Royal Society B: Biological Sciences, 2018, 373 (1748), pp.20170072. ⟨10.1098/rstb.2017.0072⟩
Philosophical Transactions of the Royal Society B: Biological Sciences, Royal Society, The, 2018, 373 (1748), pp.20170072. ⟨10.1098/rstb.2017.0072⟩
Philosophical Transactions of the Royal Society B: Biological Sciences, 2018, 373 (1748), pp.20170072. ⟨10.1098/rstb.2017.0072⟩
DNA, RNA and histone methylation is implicated in various human diseases such as cancer or viral infections, playing a major role in cell process regulation, especially in modulation of gene expression. Here we developed a convergent synthetic pathwa
Autor:
Olivier Lozach, Laurent Meijer, Arnaud Parenty, Dominique Laurent, Frédéric Alby, Nicolas Lebouvier, Christian Doerig, Martine Knibiehler, Maryvonne Frostin, Séverine Maurel, Sophie Schmitt, Dominique Dorin, Valérie Jullian, Michel Sauvain
Publikováno v:
Bioorganic and Medicinal Chemistry
Bioorganic and Medicinal Chemistry, 2006, 14 (13), pp.4477-4482. ⟨10.1016/j.bmc.2006.02.026⟩
Bioorganic and Medicinal Chemistry, Elsevier, 2006, 14 (13), pp.4477-4482. ⟨10.1016/j.bmc.2006.02.026⟩
Bioorganic and Medicinal Chemistry, 2006, 14
Bioorganic and Medicinal Chemistry, Elsevier, 2006, 14, pp.4477-4482. ⟨10.1016/j.bmc.2006.02.026⟩
Bioorganic and Medicinal Chemistry, 2006, 14 (13), pp.4477-4482. ⟨10.1016/j.bmc.2006.02.026⟩
Bioorganic and Medicinal Chemistry, Elsevier, 2006, 14 (13), pp.4477-4482. ⟨10.1016/j.bmc.2006.02.026⟩
Bioorganic and Medicinal Chemistry, 2006, 14
Bioorganic and Medicinal Chemistry, Elsevier, 2006, 14, pp.4477-4482. ⟨10.1016/j.bmc.2006.02.026⟩
As part of our search for new antimalarial drugs, we have screened for inhibitors of Pfnek-1, a protein kinase of Plasmodium falciparum, in south Pacific marine sponges. On the basis of a preliminary screening, the ethanolic crude extract of a new sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c47e105461c8d6ba29e5b1d4be352a
https://hal.science/hal-00169387
https://hal.science/hal-00169387
Autor:
Jean-Sébastien Hoffmann, Christian Moretti, Bruno David, Frédéric Alby, Christophe Cazaux, Georges Massiot, Frédéric Ausseil, Catherine Lavaud, Christophe Long, Florence Daubié, Marie-Jeanne Serrano, Martine Knibiehler
Publikováno v:
Journal of natural products. 68(7)
Five new acylphloroglucinol derivatives, mahureones A-E (1, 3-6), have been isolated from the leaves of Mahurea palustris, and their structures determined by spectroscopic means. During the isolation process, several byproducts (7-9) were formed by r
Autor:
Marie-Christine, Brezak, Muriel, Quaranta, Odile, Mondésert, Marie-Odile, Galcera, Olivier, Lavergne, Frédéric, Alby, Martine, Cazales, Véronique, Baldin, Christophe, Thurieau, Jeremiath, Harnett, Christophe, Lanco, Philip G, Kasprzyk, Gregoire P, Prevost, Bernard, Ducommun
Publikováno v:
Cancer Research
Cancer Research, American Association for Cancer Research, 2004, 64 (9), pp.3320-5
Cancer Research, American Association for Cancer Research, 2004, 64 (9), pp.3320-5
CDC25 dual-specificity phosphatases are essential regulators that dephosphorylate and activate cyclin-dependent kinase/cyclin complexes at key transitions of the cell cycle. CDC25 activity is currently considered to be an interesting target for the d
Autor:
Christophe Thurieau, Jeremiath Harnett, Véronique Baldin, Olivier Lavergne, Gregoire Prevost, Odile Mondesert, Philip G. Kasprzyk, Christophe Lanco, Frédéric Alby, Marie-Christine Brezak, Muriel Quaranta, Martine Cazales, Marie-Odile Galcera, Bernard Ducommun
Publikováno v:
Cancer Research
Cancer Research, American Association for Cancer Research, 2004, 64 (9), pp.3320-3325. ⟨10.1158/0008-5472.CAN-03-3984⟩
Cancer Research, American Association for Cancer Research, 2004, 64 (9), pp.3320-3325. ⟨10.1158/0008-5472.CAN-03-3984⟩
CDC25 dual-specificity phosphatases are essential regulators that dephosphorylate and activate cyclin-dependent kinase/cyclin complexes at key transitions of the cell cycle. CDC25 activity is currently considered to be an interesting target for the d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6296fd1c27326323771dc11ef7979703
https://hal-cnrs.archives-ouvertes.fr/hal-02353394
https://hal-cnrs.archives-ouvertes.fr/hal-02353394
Autor:
Grégoire Pierre, Prevost, Marie-Christine, Brezak, Françoise, Goubin, Odile, Mondesert, Marie-Odile, Galcera, Muriel, Quaranta, Frédéric, Alby, Olivier, Lavergne, Bernard, Ducommun
Publikováno v:
Progress in cell cycle research. 5
As essential cell cycle regulators, the CDC25 phosphatases are currently considered as potential targets for the development of novel therapeutic approaches. Here, we review the function and regulation of CDC25 phosphatases, their involvement in canc
Autor:
Véronique Baldin, Frédéric Alby, Raoul Mazars, Bernard Ducommun, Jean-Marie Darbon, Emmanuelle Guillou, Jean De Rycke
Publikováno v:
FEBS Letters
FEBS Letters, Wiley, 2001, 491, pp.261-265
FEBS Letters, Wiley, 2001, 491, pp.261-265
The bacterial cytolethal distending toxin (CDT) triggers a G2/M cell cycle arrest in eukaryotic cells by inhibiting the CDC25C phosphatase-dependent CDK1 dephosphorylation and activation. We report that upon CDT treatment CDC25C is fully sequestered