Zobrazeno 1 - 10
of 183
pro vyhledávání: '"FréDéRic Adam"'
Publikováno v:
Frontiers in Public Health, Vol 10 (2022)
IntroductionThe COVID-19 pandemic has posed an unprecedented challenge worldwide for healthcare workers (HCWs) and other hospital employees. Disruptions in work and personal life may have led to mental health problems. To prevent or limit the severit
Externí odkaz:
https://doaj.org/article/9a058b2f66274949bd1327f366e00258
Autor:
Lamia Lamrani, Frédéric Adam, Christelle Soukaseum, Cécile V. Denis, Hana Raslova, Jean‐Philippe Rosa, Marijke Bryckaert
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 6, Iss 2, Pp n/a-n/a (2022)
Abstract Background Filamin (FLN) regulates many cell functions through its scaffolding activity cross‐linking cytoskeleton and integrins. FLN was shown to inhibit integrin activity, but the exact mechanism remains unclear. Objectives The aim of th
Externí odkaz:
https://doaj.org/article/8a66c3162756480ca903cda5b86d834b
Autor:
Mahita Razanakolona, Frédéric Adam, Elsa Bianchini, François Saller, Allan de Carvalho, Jean-Luc Diehl, Cécile V. Denis, Ferhat Meziani, Delphine Borgel, Julie Helms, Marc Vasse
Publikováno v:
TH Open, Vol 05, Iss 02, Pp e220-e229 (2021)
The protein Z (PZ)-dependent plasma protease inhibitor (ZPI) is a glycoprotein that inhibits factor XIa and, in the presence of PZ, FXa. Recently, ZPI has been shown to be an acute-phase protein (APP). As usually APPs downregulate the harmful effects
Externí odkaz:
https://doaj.org/article/68423b7e0f38437d918b30b1ee14c6aa
Autor:
Annabelle Dupont, Christelle Soukaseum, Mathilde Cheptou, Frédéric Adam, Thomas Nipoti, Marc-Damien Lourenco-Rodrigues, Paulette Legendre, Valérie Proulle, Antoine Rauch, Charlotte Kawecki, Marijke Bryckaert, Jean-Philippe Rosa, Camille Paris, Catherine Ternisien, Pierre Boisseau, Jenny Goudemand, Delphine Borgel, Dominique Lasne, Pascal Maurice, Peter J. Lenting, Cécile V. Denis, Sophie Susen, Alexandre Kauskot
Publikováno v:
Haematologica, Vol 104, Iss 12 (2019)
Patients with type 2B von Willebrand disease (vWD) (caused by gain-of-function mutations in the gene coding for von Willebrand factor) display bleeding to a variable extent and, in some cases, thrombocytopenia. There are several underlying causes of
Externí odkaz:
https://doaj.org/article/c6a2a981946540fc902c3cbea7dc27d8
Autor:
Frédéric, Adam, Pauline, Jouët, Jean-Marc, Sabaté, Serge, Perrot, Claire, Franchisseur, Nadine, Attal, Didier, Bouhassira
Publikováno v:
Pain. 164:638-644
The thermal grill illusion of pain (TGIP) is a paradoxical burning pain sensation elicited by the simultaneous application of innocuous cutaneous warm and cold stimuli with a thermode ("thermal grill") consisting of interlaced heated and cooled bars.
Autor:
Josepha C. Sedzro, Frédéric Adam, Claire Auditeau, Elsa Bianchini, Allan De Carvalho, Ivan Peyron, Sadyo Daramé, Sophie Gandrille, Stella Thomassen, Tilman M. Hackeng, Olivier D. Christophe, Peter J. Lenting, Cécile V. Denis, Delphine Borgel, François Saller
Publikováno v:
Journal of Thrombosis and Haemostasis, 20(7), 1653-1664. Wiley
BACKGROUND: Protein S (PS) is a natural anticoagulant acting as a cofactor for activated protein C (APC) in the proteolytic inactivation of activated factor V (FVa) and VIII (FVIIIa), but also for tissue factor pathway inhibitor α (TFPIα) in the in
Autor:
Alexandre Kauskot, Coralie Mallebranche, Arnaud Bruneel, François Fenaille, Jean Solarz, Toscane Viellard, Miao Feng, Christelle Repérant, Jean-Claude Bordet, Sophie Cholet, Cécile V. Denis, Geneviève McCluskey, Sylvain Latour, Emmanuel Martin, Isabelle Pellier, Dominique Lasne, Delphine Borgel, Sven Kracker, Alban Ziegler, Marie Tuffigo, Benjamin Fournier, Charline Miot, Frédéric Adam
Publikováno v:
Journal of Thrombosis and Haemostasis.
Autor:
Alexandre Kauskot, Tiffany Pascreau, Frédéric Adam, Arnaud Bruneel, Christelle Reperant, Marc-Damien Lourenco-Rodrigues, Jean-Philippe Rosa, Rachel Petermann, Hélène Maurey, Claire Auditeau, Dominique Lasne, Cécile V. Denis, Marijke Bryckaert, Pascale de Lonlay, Cécile Lavenu-Bombled, Judith Melki, Delphine Borgel
Publikováno v:
Haematologica, Vol 103, Iss 12 (2018)
Externí odkaz:
https://doaj.org/article/1449f4971f1041b4aeca66901242487a
Autor:
Athanasia Stoupa, Frédéric Adam, Dulanjalee Kariyawasam, Catherine Strassel, Sanjay Gawade, Gabor Szinnai, Alexandre Kauskot, Dominique Lasne, Carsten Janke, Kathiresan Natarajan, Alain Schmitt, Christine Bole‐Feysot, Patrick Nitschke, Juliane Léger, Fabienne Jabot‐Hanin, Frédéric Tores, Anita Michel, Arnold Munnich, Claude Besmond, Raphaël Scharfmann, François Lanza, Delphine Borgel, Michel Polak, Aurore Carré
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 12, Pp n/a-n/a (2018)
Abstract The genetic causes of congenital hypothyroidism due to thyroid dysgenesis (TD) remain largely unknown. We identified three novel TUBB1 gene mutations that co‐segregated with TD in three distinct families leading to 1.1% of TUBB1 mutations
Externí odkaz:
https://doaj.org/article/9f89d1aa4ab044b1b23872b473386b2b
Autor:
Charlotte Boussard, Laure Delage, Tania Gajardo, Alexandre Kauskot, Maxime Batignes, Nicolas Goudin, Marie-Claude Stolzenberg, Camille Brunaud, Patricia Panikulam, Quentin Riller, Maryse Moya-Nilges, Jean Solarz, Christelle Reperant, Béatrice Durel, Jean-Claude Bordet, Olivier Pellé, Corinne Lebreton, Aude Magerus-Chatinet, Vithura Pirabakaran, Pablo Vargas, Sébastien Dupichaud, Marie Jeanpierre, Angélique Vinit, Mohammed Zarhrate, Cécile Masson, Nathalie Aladjidi, Peter D Arkwright, Brigitte Bader-Meunier, Sandrine Baron Joly, Joy Benadiba, Elise Bernard, Dominique Berrebi, Christine Bodemer, Martin Castelle, Fabienne Charbit-Henrion, Marwa Chbihi, Agathe Debray, Philippe Drabent, Sylvie Fraitag, Miguel Hié, Judith Landman-Parker, Ludovic Lhermitte, Despina Moshous, Pierre Rohrlich, Frank M Ruemmele, Anne Welfringer-Morin, Maud Tusseau, Alexandre Belot, Nadine Cerf-Bensussan, Marie Roelens, Capucine Picard, Bénédicte Neven, Alain Fischer, Isabelle Callebaut, Mickaël Mathieu Ménager, Fernando E Sepulveda, Frédéric Adam, Frédéric Rieux-Laucat
Publikováno v:
Blood.
Dedicator of cytokinesis (DOCK) proteins play a central role in actin cytoskeleton regulation. This is highlighted by the DOCK2 and DOCK8 deficiencies leading to actinopathies and immune deficiencies. DOCK8 and DOCK11 activate CDC42, a RHO-GTPase inv