Zobrazeno 1 - 10
of 33 036
pro vyhledávání: '"Foxp3+"'
Publikováno v:
Clinical Immunology Communications, Vol 6, Iss , Pp 15-25 (2024)
Mutations in NF-κB-related molecules result in combined immunodeficiency characterized by recurrent infection. In this study, we aimed to investigate the association between mutations in NF-κB family members, RELA, RELB, and RELC, and regulatory T
Externí odkaz:
https://doaj.org/article/2ddb4da3ab984092ab6cf56b19509537
Clinical and prognostic effects of microvascular density and FOXP3 positive T cells in breast cancer
Autor:
Yaşar Culha, Cigdem Ozdemir, Sena Ece Davarci, Beyza Ünlü, Mehmet Olgun A. K., Hacer Demir, Meltem Baykara
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract There are conflicting data regarding the prognostic effect of microvascular density (MVD) in breast cancer and its molecular subtypes. It is thought that high levels of FOXP3 + T cells in breast cancer are associated with poor prognosis. How
Externí odkaz:
https://doaj.org/article/dbc4bfd965764041959b2a5c87bab6ba
Autor:
Maria Isabel Carvalho, Ricardo Silva-Carvalho, Justina Prada, Carla Pinto, Hugo Gregório, Luis Lobo, Isabel Pires, Felisbina L. Queiroga
Publikováno v:
Veterinary Quarterly, Vol 44, Iss 1, Pp 1-12 (2024)
Transforming growth factor-β (TGFβ) and FoxP3 regulatory T cells (Treg) are involved in human breast carcinogenesis. This topic is not well documented in canine mammary tumors (CMT). In this work, the tumoral TGFβ expression was assessed by immuno
Externí odkaz:
https://doaj.org/article/9dcc46300afa4ae9b7d7aa1ea2ba25a5
Autor:
Becker A, Röhrich K, Leske A, Heinicke U, Knape T, Kannt A, Trümper V, Sohn K, Wilken-Schmitz A, Neb H, Adam EH, Laux V, Parnham MJ, Onasch V, Weigert A, Zacharowski K, von Knethen A
Publikováno v:
ImmunoTargets and Therapy, Vol Volume 13, Pp 595-616 (2024)
Antonia Becker,1 Karoline Röhrich,1 Amanda Leske,1 Ulrike Heinicke,1 Tilo Knape,2 Aimo Kannt,2,3 Verena Trümper,4 Kai Sohn,5 Annett Wilken-Schmitz,1 Holger Neb,1 Elisabeth H Adam,1 Volker Laux,2 Michael J Parnham,2 Valerie Onasch,4 Andreas Weigert,
Externí odkaz:
https://doaj.org/article/deb4c474a3804763b80e9aa908eb6669
Publikováno v:
Exploration of Immunology, Vol 4, Iss 5, Pp 640-657 (2024)
The impaired function of regulatory T (Treg) cells and the imbalance of Treg/Th17 cells play a central role in developing autoimmune diseases such as systemic lupus erythematosus (SLE). Treg cells are crucial for maintaining immune homeostasis and to
Externí odkaz:
https://doaj.org/article/59550e72828c4c598e075e79010c057c
Publikováno v:
Breast Cancer: Targets and Therapy, Vol Volume 16, Pp 705-723 (2024)
Chunlei Tan,1 Jinling Xu,2 Shiyuan Zhang,1 Shuqiang Liu,1 Xiaotian Yang,1 Danping Wu,1 Boqian Yu,1 Yuanxi Huang1 1Department of Breast Surgery, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang, 150081, People’s Republic of China; 2En
Externí odkaz:
https://doaj.org/article/3f97c95570ab47faba480a288558d2db
Autor:
Asami Suto, Takeo Minaguchi, Nan Qi, Kaoru Fujieda, Hiroya Itagaki, Yuri Tenjimbayashi, Ayumi Shikama, Nobutaka Tasaka, Azusa Akiyama, Sari Nakao, Chigusa Nakahashi-Oda, Yusuke Kobayashi, Akira Shibuya, Toyomi Satoh
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Regulatory T (Treg) cells reportedly play crucial roles in tumor angiogenesis as well as antitumor immunity. In order to explore their therapeutic potential, we investigated the precise prognostic impact of Treg markers in endomet
Externí odkaz:
https://doaj.org/article/6f42ba3886614c63a495397bd9f88619
Publikováno v:
Zhongliu Fangzhi Yanjiu, Vol 51, Iss 7, Pp 561-566 (2024)
ObjectiveTo investigate the potential significance of FOXP3 expression in BRCA1/2-mutant breast cancer. MethodsA total of 48 BRCA mutation carriers (16 with BRCA1 and 32 with BRCA2) and 78 age-matched non-carriers were included in this study. Immunoh
Externí odkaz:
https://doaj.org/article/afc5471d38904448bc059fe915df2e14
Autor:
Fabrizio Leone, Alessandra Gori, Bianca Laura Cinicola, Giulia Brindisi, Vittorio Maglione, Caterina Anania, Anna Maria Zicari
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
While Trisomy X syndrome is typically characterized by developmental and cognitive variations, it is not commonly associated with immunodeficiencies. We report the unique case of a 6-year-old girl with Trisomy X presenting with selective IgA deficien
Externí odkaz:
https://doaj.org/article/405e1fdb81f24669a50820400751d8d2
Publikováno v:
Annals of Medicine, Vol 56, Iss 1 (2024)
Background FOXP3 is a transcription factor that regulates the development and function of Treg, playing an essential role in preventing autoimmune diseases. Variation in FOXP3 can impair the function of Treg cells, thus destroying their inhibitory ca
Externí odkaz:
https://doaj.org/article/ffb8d36a6f174242908245a5c50e845b