The PACS-2 protein and trafficking motifs in CCHFV Gn and Gc cytoplasmic domains govern CCHFV assembly

Autor: Anupriya Gautam, Alexandre Lalande, Maureen Ritter, Natalia Freitas, Solène Lerolle, Lola Canus, Fouzia Amirache, Vincent Lotteau, Vincent Legros, François-Loïc Cosset, Cyrille Mathieu, Bertrand Boson

Publikováno v: Emerging Microbes and Infections, Vol 13, Iss 1 (2024)

The Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne bunyavirus that causes high mortality in humans. This enveloped virus harbors two surface glycoproteins (GP), Gn and Gc, that are released by processing of a glycoprotein precursor com

Externí odkaz: https://doaj.org/article/72ad31323c9f4a0b99c68e57b940f6b5

Enveloped viruses distinct from HBV induce dissemination of hepatitis D virus in vivo

Autor: Jimena Perez-Vargas, Fouzia Amirache, Bertrand Boson, Chloé Mialon, Natalia Freitas, Camille Sureau, Floriane Fusil, François-Loïc Cosset

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)

Hepatitis D virus (HDV) relies on a helper virus to package and transmit its ribonucleoprotein (RNP). Here, Perez-Vargas et al. show that HDV can use envelope proteins from HBV-unrelated viruses, including HCV and flaviviruses, to propagate in vitro

Externí odkaz: https://doaj.org/article/442be38e30c54650a97b9c860a6723d3

Hepatitis D virus interferes with hepatitis B virus RNA production via interferon-dependent and -independent mechanisms

Autor: Julie Lucifora, Dulce Alfaiate, Caroline Pons, Maud Michelet, Ricardo Ramirez, Floriane Fusil, Fouzia Amirache, Axel Rossi, Anne-Flore Legrand, Emilie Charles, Serena Vegna, Rayan Farhat, Michel Rivoire, Guillaume Passot, Nicolas Gadot, Barbara Testoni, Charlotte Bach, Thomas F. Baumert, Anastasia Hyrina, Rudolf K. Beran, Fabien Zoulim, Andre Boonstra, Hildegard Büning, Eloi R. Verrier, François-Loïc Cosset, Simon P. Fletcher, Anna Salvetti, David Durantel

Publikováno v: Journal of Hepatology
Journal of Hepatology, In press, ⟨10.1016/j.jhep.2023.01.005⟩
Journal of Hepatology, 78(5), 958-970. Elsevier

Background & Aims: Chronic coinfection with HBV and HDV leads to the most aggressive form of chronic viral hepatitis. Herein, we aimed to elucidate the molecular mechanisms underlying the widely reported observation that HDV interferes with HBV in mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc3b3eff3a87ef013cb5c6dbae104bda

Author response: A fusion peptide in preS1 and the human protein disulfide isomerase ERp57 are involved in hepatitis B virus membrane fusion process

Autor: Floriane Fusil, Christophe Combet, Alessandra Carbone, Fouzia Amirache, Jimena Pérez-Vargas, Anja Böckmann, Elin Teppa, Natalia Freitas, Rémi Pereira de Oliveira, François-Loïc Cosset, Bertrand Boson

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3d8005bda1dbe03400815382698ea22d
https://doi.org/10.7554/elife.64507.sa2

Baboon envelope LVs efficiently transduced human adult, fetal, and progenitor T cells and corrected SCID-X1 T-cell deficiency

Autor: David Fenard, Ornellie Bernadin, Anais Girard-Gagnepain, Camille Lévy, Chantal Lagresle-Peyrou, Kuiying Ma, Rana Mhaidly, Hanem Sadek, Marina Cavazzana, Fouzia Amirache, Caroline Costa, Ranjita Devi Moirangthem, Isabelle André, François-Loïc Cosset, Els Verhoeyen, Christian Reimann, Didier Nègre, Agata Cieslak, Vahid Asnafi

Publikováno v: Blood Advances
Blood Advances, The American Society of Hematology, 2019, 3 (3), pp.461-475. ⟨10.1182/bloodadvances.2018027508⟩
Blood Advances, 2019, 3 (3), pp.461-475. ⟨10.1182/bloodadvances.2018027508⟩

T cells represent a valuable tool for treating cancers and infectious and inherited diseases; however, they are mainly short-lived in vivo. T-cell therapies would strongly benefit from gene transfer into long-lived persisting naive T cells or T-cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc71d6d3ddfc5a388ab66cb716a918bb
https://hal.archives-ouvertes.fr/hal-02365989