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Autor:
Bale, Shridhar, Martiné, Alexandra, Wilson, Richard, Behrens, Anna Janina, Fourn, Valérie Le, Val, Natalia de, Sharma, Shailendra K., Tran, Karen, Torres, Jonathan L., Girod, Pierre Alain, Ward, Andrew B., Crispin, Max, Wyatt, Richard T.
Publikováno v:
Frontiers in Immunology
Native flexibly linked (NFL) HIV-1 envelope glycoprotein (Env) trimers are cleavage-independent and display a native-like, well-folded conformation that preferentially displays broadly neutralizing determinants. The NFL platform simplifies large-scal