Zobrazeno 1 - 10
of 327
pro vyhledávání: '"Fourcaudot A"'
Autor:
Christopher E. Shannon, Terry Bakewell, Marcel J. Fourcaudot, Iriscilla Ayala, Annie A. Smelter, Edgar A. Hinostroza, Giovanna Romero, Mara Asmis, Leandro C. Freitas Lima, Martina Wallace, Luke Norton
Publikováno v:
Molecular Metabolism, Vol 88, Iss , Pp 102005- (2024)
Objective: The mitochondrial pyruvate carrier (MPC) occupies a critical node in intermediary metabolism, prompting interest in its utility as a therapeutic target for the treatment of obesity and cardiometabolic disease. Dysregulated nutrient metabol
Externí odkaz:
https://doaj.org/article/7d18efd12b474aa18d24badc4b6d8c53
Autor:
Shannon, Christopher E., Bakewell, Terry, Fourcaudot, Marcel J., Ayala, Iriscilla, Smelter, Annie A., Hinostroza, Edgar A., Romero, Giovanna, Asmis, Mara, Freitas Lima, Leandro C., Wallace, Martina, Norton, Luke
Publikováno v:
In Molecular Metabolism October 2024 88
Autor:
Malka, Ronit, Silliman, David T., Fourcaudot, Andrea, Nguyen, Jesse Q., Leung, Kai P., Decker, John F., Dion, Gregory R.
Publikováno v:
In Burns February 2025 51(1)
Autor:
Iriscilla Imabary Ayala, Skanda K Hebbale, Chris E. Shannon, Ivan Valdez, Marcel Fourcaudot, Terry M. Bakewell, Madelaine Sholto, Thomas Vallim, Sami Heikkinen
Publikováno v:
Journal of Clinical and Translational Science, Vol 8, Pp 7-7 (2024)
OBJECTIVES/GOALS: Single nucleotide polymorphisms in the transcription factor 7-like 2 (TCF7L2) gene are associated with Type 2 Diabetes (T2D) and nonalcoholic fatty liver disease (NAFLD). The metabolic function of TCF7L2 in the liver remains to be f
Externí odkaz:
https://doaj.org/article/d85fd34c73d146c59050542915dc13ac
Autor:
Shannon, Chris E., Ragavan, Mukundan, Palavicini, Juan Pablo, Fourcaudot, Marcel, Bakewell, Terry M, Valdez, Ivan A., Ayala, Iriscilla, Jin, Eunsook S., Madesh, Muniswamy, Han, Xianlin, Merritt, Matthew E., Norton, Luke
Publikováno v:
In Molecular Metabolism March 2021 45
Autor:
Iriscilla I. Ayala, Skanda K Hebbale, Chris E. Shannon, Ivan Valdez, Marcel Fourcaudot, Terry M. Bakewell, Madelaine Sholto, Thomas Vallim, Sami Heikkinen
Publikováno v:
Journal of Clinical and Translational Science, Vol 7, Pp 103-103 (2023)
OBJECTIVES/GOALS: Single nucleotide polymorphisms in the transcription factor 7-like 2 (TCF7L2) gene are associated with Type 2 Diabetes (T2D) and nonalcoholic fatty liver disease (NAFLD). The metabolic function of TCF7L2 in the liver remains to be f
Externí odkaz:
https://doaj.org/article/8e32245c74074c31875e6eb756175b22
Autor:
Liza D. Morales, Douglas T. Cromack, Devjit Tripathy, Marcel Fourcaudot, Satish Kumar, Joanne E. Curran, Melanie Carless, Harald H. H. Göring, Shirley L. Hu, Juan Carlos Lopez-Alvarenga, Kristina M. Garske, Päivi Pajukanta, Kerrin S. Small, Craig A. Glastonbury, Swapan K. Das, Carl Langefeld, Robert L. Hanson, Wen-Chi Hsueh, Luke Norton, Rector Arya, Srinivas Mummidi, John Blangero, Ralph A. DeFronzo, Ravindranath Duggirala, Christopher P. Jenkinson
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Insulin is an essential hormone that regulates glucose homeostasis and metabolism. Insulin resistance (IR) arises when tissues fail to respond to insulin, and it leads to serious health problems including Type 2 Diabetes (T2D). Obesity is a
Externí odkaz:
https://doaj.org/article/1659f6d5d12d42ebbff7be8f7ccaf33e
Autor:
Karna, S. L. Rajasekhar, Nguyen, Jesse Q., Evani, Shankar Jaikishan, Qian, Li-Wu, Chen, Ping, Abercrombie, Johnathan J., Sebastian, Eliza A., Fourcaudot, Andrea B., Leung, Kai P.
Publikováno v:
In Microbial Pathogenesis October 2020 147
Autor:
Juan P. Palavicini, Alberto Chavez-Velazquez, Marcel Fourcaudot, Devjit Tripathy, Meixia Pan, Luke Norton, Ralph A. DeFronzo, Christopher E. Shannon
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
The insulin-sensitizer pioglitazone exerts its cardiometabolic benefits in type 2 diabetes (T2D) through a redistribution of body fat, from ectopic and visceral areas to subcutaneous adipose depots. Whereas excessive weight gain and lipid storage in
Externí odkaz:
https://doaj.org/article/335d5896954c4b0ea9323a843dc2c1dd
Autor:
Subramanya Srikantan, Yilun Deng, Zi-Ming Cheng, Anqi Luo, Yuejuan Qin, Qing Gao, Glaiza-Mae Sande-Docor, Sifan Tao, Xingyu Zhang, Nathan Harper, Chris E. Shannon, Marcel Fourcaudot, Zhi Li, Balakuntalam S. Kasinath, Stephen Harrison, Sunil Ahuja, Robert L. Reddick, Lily Q. Dong, Muhammad Abdul-Ghani, Luke Norton, Ricardo C. T. Aguiar, Patricia L. M. Dahia
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
TMEM127 is a tumor suppressor protein, loss of which predisposes to catecholamine-secreting tumors. Here the authors show that TMEM127 expression is modulated by nutritional status and that it has a role in regulating organismal insulin sensitivity.
Externí odkaz:
https://doaj.org/article/759408e47c5a4d35885debb0d56f6eb3