Výsledky vyhledávání - "Fouad M soliman"

Akademický článek

Dual-target ligand discovery for Alzheimer’s disease: triphenylphosphoranylidene derivatives as inhibitors of acetylcholinesterase and β-amyloid aggregation

Autor: Marwa El-Hussieny, Mansoura A. Abd-El-Maksoud, Fouad M. Soliman, Marwa A. Fouad, Mohamed K. El-Ashrey

Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)

Alzheimer disease (AD) is one of the major neurodegenerative diseases that could not be prevented or completely cured and may lead to death. Here, we target AChE and β-amyloid proteins. Synthesising new triphenylphosphporanylidene derivatives based

Externí odkaz: https://doaj.org/article/e416c74bfdd34652aeed2fa4c0312ebf

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Chemistry of Phosphorus Ylides. Part 47. Synthesis of Organophosphorus and Selenium Pyrazolone Derivatives, Their Antioxidant Activity, and Cytotoxicity against MCF7 and HepG2

Autor: Fouad M. Soliman, Mansoura A. Abd-El-Maksoud, Abdel-Tawab H. Mossa, Marwa El-Hussieny, H. M. Awad

Publikováno v: Russian Journal of General Chemistry. 90:2356-2364

Reaction of oxobutenyl- and oxophenylpropenyl-phenylpyrazolones with the active phosphacumulenes, iminovinylidene- and oxovinylidenetriphenylphosphoranes has led to pyranopyrazole and phosphoranylidenepyranopyrazole, respectively. Reaction of the pyr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::80113ef38eb1ea8e00d6f722407f9f10
https://doi.org/10.1134/s1070363220120208

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The synthesis and antineoplastic activities of thiaziridine, sulfidometylphosphonium, and dithiaphosphitane-sulfide against the Ehrlich ascites carcinoma

Autor: Shaimaa T. Mansour, Ahmed I. Hashem, Mansoura A. Abd‐El‐Maksoud, Marwa El‐Hussieny, Aida I. El‐Makawy, Sekena H. Abdel‐Aziem, Fouad M. Soliman

Publikováno v: Fundamentalclinical pharmacologyREFERENCES. 36(3)

Phosphonium compounds offer an attractive branch of research that chemists and biologists apply for producing many novel drugs for various applications, and its polymeric ingredients are composed of quaternary ammonium and phosphonium salts. The reac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8be25d758d86507e2ea1b2e11ba1cff4
https://pubmed.ncbi.nlm.nih.gov/34984731

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Chemistry of Phosphorus Ylides Part 42: Reaction of Dipyridyl Ethanedione with Phosphorus Reagents. Cytotoxic Activity of Phosphanylidene-Cyclobutane, Oxaphosphetane, and Pyridazinone

Autor: Mansoura Ali Abd-El-Maksoud, Fouad M. Soliman, Abdelmohsen Soliman, Fouad M soliman, Soher Maigali, Marwa El-Hussieny

Publikováno v: Phosphorus, Sulfur, and Silicon and the Related Elements. 190:1845-1856

1,2-Bis(2-pyridyl)ethane-1,2-dione was allowed to react with different phosphorus nucleophiles. Treatment of the 1,2-bis(2-pyridyl)ethane-1,2-dione with the active phosphacumulene ylides, (N-phenyl...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4793d20d82cfc890ffea5619c8b12a9d
https://doi.org/10.1080/10426507.2015.1025904

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Chemistry of Phosphonium Ylides. Part 39: Facile Synthesis of Aziridine, Pyridine, Pyrolotriazole Chromenones and Azaphosphinin Chromenones as Antitumor Agents

Autor: Soher Maigali, Mansoura Ali Abd-El-Maksoud, Fouad M soliman, Fouad M. Soliman

Publikováno v: Journal of Heterocyclic Chemistry. 51:1830-1837

The reaction of 4-azido-2-oxo-2H-chromene-3-carbaldehyde with the active nucleophilic phosphacumulenes yielded the corresponding phosphanylidene-aziridines and chromeno-pyrolo-triazoles. On the other hand, the reaction of the allylic phosphonium ylid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1e1ad686f98ce42d70a2f9bb3a1c0aa6
https://doi.org/10.1002/jhet.2205

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Chemistry of Phosphorus Ylides. Part 40. Synthesis of Pyrazoles by the [3 + 2] Cycloaddition of Diazo Compounds with Wittig Reagents as Antimicrobial Compounds

Autor: Mansoura Ali Abd-El-Maksoud, Maysa Moharam, Fouad M. Soliman, Fouad M soliman, Soher Maigali

Publikováno v: Journal of Heterocyclic Chemistry. 52:834-840

A comparative study between the reactions of active phosphacumulenes and stabilized phosphonium ylides on some diazo compounds have been performed. A number of substituted phosphanylidene spiro pyrazoles have been synthesized from the reaction of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::608037d42f0f850f251a7c4ce86fb33f
https://doi.org/10.1002/jhet.2131

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Chemistry of Phosphorus Ylides. Part 37. The Reaction of Phosphonium Ylides with Indoles and Naphthofurans. Synthesis of Phosphanylidenes, Pyrans, Cyclobutenes, and Pyridazine as Antitumor Agents

Autor: Soher Maigali, Marwa El-Hussieny, Fouad M soliman, Fouad M. Soliman

Publikováno v: Journal of Heterocyclic Chemistry. 52:15-23

The reaction of the stabilized phosphonium ylides 2a, 2b with indolinones 1a, 1b and naphthofuranone 13 afforded the corresponding propylidene and ethylidene derivatives 4a, 4b, 4c, 4d and 14a, 14b. On the other hand, the active phosphacumulenes 5a,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8daf19588a27210225ef7b93734fdded
https://doi.org/10.1002/jhet.1911

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