Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Fotini Tsamis"'
Publikováno v:
Virology. 352(2):477-484
HIV-1 coreceptors are attractive targets for novel antivirals. Here, inhibition of entry by two classes of CCR5 antagonists was investigated. We confirmed previous findings that HIV-1 isolates vary greatly in their sensitivity to small molecule inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f7a0e04c7417730ecac02b9aade82cf
Autor:
Stuart W. McCombie, Thomas P. Sakmar, Tatjana Dragic, Fotini Tsamis, Bahige M. Baroudy, Christoph Seibert, John W. Clader, John P. Moore, Anandan Palani, Svetlana Gavrilov, Shawn E. Kuhmann, Jayaram R. Tagat, Steven O. Smith, Weiwen Ying
Publikováno v:
Virology. 349(1):41-54
The CC-chemokine receptor 5 (CCR5) is the major coreceptor for macrophage-tropic (R5) HIV-1 strains. Several small molecule inhibitors of CCR5 that block chemokine binding and HIV-1 entry are being evaluated as drug candidates. Here we define how CCR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37bf7b55794ac5ea33b739e547cfe2a9
Autor:
Tom Ketas, Jayaram R. Tagat, John W. Clader, Thomas P. Sakmar, Bahige M. Baroudy, Alexandra Trkola, Fotini Tsamis, Christoph Seibert, Svetlana Gavrilov, Francis Kajumo, Anadan Palani, John P. Moore, Shawn E. Kuhmann, Tatjana Dragic, Stuart W. McCombie
Publikováno v:
Journal of Virology. 77:5201-5208
Human immunodeficiency virus type 1 (HIV-1) entry is mediated by the consecutive interaction of the envelope glycoprotein gp120 with CD4 and a coreceptor such as CCR5 or CXCR4. The CCR5 coreceptor is used by the most commonly transmitted HIV-1 strain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f00b025062d7674338c9a7ff16a42b5
https://doi.org/10.1128/jvi.77.9.5201-5208.2003
https://doi.org/10.1128/jvi.77.9.5201-5208.2003
Autor:
Fotini Tsamis, Robert J. Durso, Lise Boussemart, Tatjana Dragic, Catherine Manix, William C. Olson, Emmanuel Cormier, Jason P. Gardner
Target cell tropism of enveloped viruses is regulated by interactions between viral and cellular factors during transmission, dissemination, and replication within the host. Binding of viral envelope glycoproteins to specific cell-surface receptors d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::676ff2841a5693ebd27d5af883a9ae18
https://europepmc.org/articles/PMC521122/
https://europepmc.org/articles/PMC521122/
