Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Fotini Karavassili"'
Autor:
Maria Spiliopoulou, Alexandros Valmas, Dimitris-Panagiotis Triandafillidis, Christos Kosinas, Andrew Fitch, Fotini Karavassili, Irene Margiolaki
Publikováno v:
Crystals, Vol 10, Iss 2, p 54 (2020)
Providing fundamental information on intra/intermolecular interactions and physicochemical properties, the three-dimensional structural characterization of biological macromolecules is of extreme importance towards understanding their mechanism of ac
Externí odkaz:
https://doaj.org/article/351aaf06402443078ab54b7518ef1a0c
Autor:
Fotini Karavassili, Alexandros Valmas, Stavroula Fili, Christos D. Georgiou, Irene Margiolaki
Publikováno v:
Biomolecules, Vol 7, Iss 3, p 63 (2017)
Human insulin (HI) is a well-characterized natural hormone which regulates glycose levels into the blood-stream and is widely used for diabetes treatment. Numerous studies have manifested that despite significant efforts devoted to structural charact
Externí odkaz:
https://doaj.org/article/faf2e27bc31a4257a8c6218af0e63ad1
Autor:
Dimitris P. Triandafillidis, Fotini Karavassili, Maria Spiliopoulou, Alexandros Valmas, Maria Athanasiadou, George Nikolaras, Stavroula Fili, Paraskevi Kontou, Matthew W. Bowler, Christos T. Chasapis, Robert B. Von Dreele, Andrew N. Fitch, Irene Margiolaki
Publikováno v:
Acta Crystallographica Section D Structural Biology. 79:374-386
The polymorphism of human insulin upon pH variation was characterized via X-ray powder diffraction, employing a crystallization protocol previously established for co-crystallization with phenolic derivatives. Two distinct rhombohedral (R3) polymorph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc56944493a6d7f38857aaf71941c257
https://doi.org/10.1107/s2059798323001328
https://doi.org/10.1107/s2059798323001328
Autor:
Mickael Morin, Stavroula Fili, Aikaterini J. Filopoulou, Irene Margiolaki, Fotini Karavassili, M. L. Reinle-Schmitt, Anastasia Piskopou, Magdalini Christopoulou, Maria Spiliopoulou, Andrew N. Fitch, Fabia Gozzo, Christos T. Chasapis, Eleftheria Rosmaraki, Detlef Beckers, Alexandros Valmas, Thomas Degen, Polyxeni Papadea, Dimitris-Panagiotis Triandafillidis
Publikováno v:
Journal of Applied Crystallography. 54:963-975
Regular injections of insulin provide life-saving benefits to millions of diabetics. Apart from native insulin and insulin analogue formulations, microcrystalline insulin suspensions are also commercially available. The onset of action of the current
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eae586d22f9a0e84ae960220d2cd210b
https://doi.org/10.1107/s160057672100426x
https://doi.org/10.1107/s160057672100426x
Autor:
Stavroula Fili, Fotini Karavassili, Kleomenis Barlos, Alexandros Valmas, Mickael Morin, Christos Kosinas, Dimitris Panagiotis Triandafillidis, Fabia Gozzo, Mathilde Reinle-Schmitt, Irene Margiolaki, Maria Spiliopoulou, Kostas K. Barlos
Publikováno v:
Acta Crystallographica Section A Foundations and Advances. 77:186-195
Advances in instrumentation, as well as the development of powerful crystallographic software have significantly facilitated the collection of high-resolution diffraction data and have made X-ray powder diffraction (XRPD) particularly useful for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cebe20238cb6eba67abf6fac8a5bd574
https://doi.org/10.1107/s2053273321001698
https://doi.org/10.1107/s2053273321001698
Autor:
Fotini Karavassili, Alexandros Valmas, Detlef Beckers, Manfred S. Weiss, Christos Kosinas, Andrew N. Fitch, Thomas Degen, Dimitris Panagiotis Triandafillidis, Fabia Gozzo, Nikolaos Parthenios, Mihaela Pop, Mathilde Reinle-Schmitt, Irene Margiolaki, J. Wollenhaupt, Maria Spiliopoulou
Publikováno v:
Acta Crystallographica Section D Structural Biology. 76:1065-1079
This study focuses on the polymorphism of human insulin (HI) upon the binding of the phenolic derivativesp-coumaric acid ortrans-resveratrol over a wide pH range. The determination of the structural behaviour of HI via X-ray powder diffraction (XRPD)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb31093791e8a0171ad28e0ea33a81b6
https://doi.org/10.1107/s205979832001195x
https://doi.org/10.1107/s205979832001195x
Autor:
Alexandros Valmas, Gerd Schluckebier, Fotini Karavassili, Maria Dimarogona, Mathias Norrman, Andrew N. Fitch, A. E. Giannopoulou, Irene Margiolaki, Detlef Beckers, Stavroula Fili
Publikováno v:
Acta Crystallographica Section D Structural Biology. 76:366-374
In this study, the first crystal structure of a novel crystal form of human insulin bound tometa-cresol in an acidic environment is reported. The combination of single-crystal and powder X-ray diffraction crystallography led to the detection of a pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c3cef08d07981af5615d4d0d6a23f1b
https://doi.org/10.1107/s2059798320002545
https://doi.org/10.1107/s2059798320002545
Autor:
S. Trampari, Stavroula Fili, Fotini Karavassili, Maria Spiliopoulou, A. N. Fitch, Souzana Logotheti, Thomas Degen, Irene Margiolaki, Gwilherm Nénert, S. Saslis, Alexandros Valmas, Detlef Beckers
Publikováno v:
Journal of Applied Crystallography. 52:816-827
Variation of relative humidity (rH) greatly affects the internal order of solvent-based protein crystals, and the rearrangement of molecules can be efficiently recorded in distinct diffraction patterns. This study focuses on this topic, reporting the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee8360d6543f38265089f1e299d349f5
https://doi.org/10.1107/s1600576719009919
https://doi.org/10.1107/s1600576719009919
Autor:
M. Calamiotou, Maria Spiliopoulou, Fotini Karavassili, S. Saslis, Irene Margiolaki, S. Trampari, A. N. Fitch, Souzana Logotheti, Stavroula Fili, Thomas Degen, Gwilherm Nénert, Alexandros Valmas, Detlef Beckers
Publikováno v:
Journal of Applied Crystallography. 51:1671-1683
The effect of relative humidity (rH) on protein crystal structures, an area that has attracted high scientific interest during the past decade, is investigated in this study on hen egg-white lysozyme (HEWL) polycrystalline precipitatesvia in situlabo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3acfc51ea7dcb5821448e453c321dae
https://doi.org/10.1107/s1600576718013936
https://doi.org/10.1107/s1600576718013936
Autor:
Andrew N. Fitch, Julie Lichière, Magdalini Christopoulou, Nicolas Papageorgiou, Bruno Canard, Alexandros Valmas, Irene Margiolaki, Fotini Karavassili, Stavroula Fili, Maria Spiliopoulou, Nikos Nikolopoulos, Detlef Beckers, Christos Kosinas, Konstantinos Bastalias, Eleftheria Rosmaraki, Thomas Degen, Bruno Coutard
Publikováno v:
Zeitschrift für Kristallographie - Crystalline Materials. 233:309-316
Flavivirus infections often provoke life-threatening diseases of epidemic magnitudes, thus extensive research is currently directed towards the development of efficient vaccines and approved antiviral compounds. We present here the expression, purifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::136de2446f79bc0b581831418de12c87
https://doi.org/10.1515/zkri-2017-2091
https://doi.org/10.1515/zkri-2017-2091