Výsledky vyhledávání - "Foteinos-Ioannis D. Dimitrakopoulos"

Akademický článek

Genetic Variations of CD40 and LTβR Genes Are Associated With Increased Susceptibility and Clinical Outcome of Non-Small-Cell Carcinoma Patients

Autor: Foteinos-Ioannis D. Dimitrakopoulos, Anna G. Antonacopoulou, Anastasia E. Kottorou, Melpomeni Kalofonou, Nikolaos Panagopoulos, Dimitrios Dougenis, Thomas Makatsoris, Vasiliki Tzelepi, Angelos Koutras, Haralabos P. Kalofonos

Publikováno v: Frontiers in Oncology, Vol 11 (2021)

BackgroundImmune system-related receptors CD40 (tumor necrosis factor receptor superfamily member 5), BAFFR (tumor necrosis factor receptor superfamily member 13C), and LTβR (tumor necrosis factor receptor superfamily member 3) play a pivotal role i

Externí odkaz: https://doaj.org/article/c8a31c79958046baaea54e62931e3ee1

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Akademický článek

Expression Of Intracellular Components of the NF-κB Alternative Pathway (NF-κB2, RelB, NIK and Bcl3) is Associated With Clinical Outcome of NSCLC Patients

Autor: Foteinos-Ioannis D. Dimitrakopoulos, Anna G. Antonacopoulou, Anastasia E. Kottorou, Nikolaos Panagopoulos, Fotini Kalofonou, Fotios Sampsonas, Chrisoula Scopa, Melpomeni Kalofonou, Angelos Koutras, Thomas Makatsoris, Dimitrios Dougenis, Helen Papadaki, Malcolm Brock, Haralabos P. Kalofonos

Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)

Abstract A growing number of studies has shed light on the role of the NF-κΒ in non-small-cell lung cancer (NSCLC). To address the significance of major effectors of the NF-κΒ alternative pathway, we investigated the relationship between NF-κΒ2

Externí odkaz: https://doaj.org/article/90d7b523d73d42dd8591096c779df15c

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Akademický článek

Exceptional response to nivolumab of a heavily pre-treated patient with metastatic renal-cell cancer: from a case report to molecular investigation and future perspectives

Autor: Foteinos-Ioannis D. Dimitrakopoulos, Eleni Kourea, George Nasioulas, Eirini Papadopoulou, Achilles Nikolakopoulos, Despoina Spyropoulou, Anastasia Kottorou, Andreas Karatzas, Haralabos P. Kalofonos, Angelos Koutras

Publikováno v: Therapeutic Advances in Medical Oncology, Vol 12 (2020)

Immunotherapy may result in long-lasting exceptional clinical responses, the molecular background of which is inadequately understood. Here, we present the case of a 63-year-old patient with a past medical history of renal cancer who relapsed many ye

Externí odkaz: https://doaj.org/article/1b8c4ddadd5b4d9d9bb369423fecc871

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Supplementary Table S2 from The Fire Within: NF-κB Involvement in Non–Small Cell Lung Cancer

Autor: Haralabos P. Kalofonos, Melpomeni Kalofonou, Anastasia E. Kottorou, Foteinos-Ioannis D. Dimitrakopoulos

Supplementary Table S2. Published studies on genetic variations of NF-κB family members and their clinical significance in NSCLC.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b1c82c87ae3fcad35c49c464821cd3c
https://doi.org/10.1158/0008-5472.22425417.v1

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Supplementary Figure 1 from The Fire Within: NF-κB Involvement in Non–Small Cell Lung Cancer

Autor: Haralabos P. Kalofonos, Melpomeni Kalofonou, Anastasia E. Kottorou, Foteinos-Ioannis D. Dimitrakopoulos

Supplementary Figure S1. Hallmarks of lung cancer influenced by NF-κB activity.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6210ba999de79b46629e6b6e33336338
https://doi.org/10.1158/0008-5472.22425423

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Data from The Fire Within: NF-κB Involvement in Non–Small Cell Lung Cancer

Autor: Haralabos P. Kalofonos, Melpomeni Kalofonou, Anastasia E. Kottorou, Foteinos-Ioannis D. Dimitrakopoulos

Thirty-four years since its discovery, NF-κB remains a transcription factor with great potential for cancer therapy. However, NF-κB–targeted therapies have yet to find a way to be clinically translatable. Here, we focus exclusively on the role of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::862f11defaddefc1eeefd9caa436adb8
https://doi.org/10.1158/0008-5472.c.6512031.v1

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Ras suppressor-1 (RSU1) exerts a tumor suppressive role with prognostic significance in lung adenocarcinoma

Autor: Sofia Nikou, Marina Arbi, Foteinos-Ioannis D. Dimitrakopoulos, Argiro Kalogeropoulou, Christina Geramoutsou, Vasiliki Zolota, Haralabos P. Kalofonos, Stavros Taraviras, Zoi Lygerou, Vasiliki Bravou

Publikováno v: Clinical and experimental medicine.

Ras suppressor-1 (RSU1), originally described as a suppressor of Ras oncogenic transformation, localizes to focal adhesions interacting with the ILK-PINCH-PARVIN (IPP) complex that exerts a well-established oncogenic role in cancer. However, RSU1 imp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3a817ea2b802a136c09d4374516af78
https://pubmed.ncbi.nlm.nih.gov/35729367

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