Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Foteini Mourkioti"'
Publikováno v:
Skeletal Muscle, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract Background Neurovascular cells have wide-ranging implications on skeletal muscle biology regulating myogenesis, maturation, and regeneration. Although several in vitro studies have investigated how motor neurons and endothelial cells interac
Externí odkaz:
https://doaj.org/article/1b18cddb03cb428da82c8470344d295f
Autor:
Nuoying Ma, Foteini Mourkioti
Publikováno v:
STAR Protocols, Vol 5, Iss 1, Pp 102772- (2024)
Summary: Quiescent skeletal muscle stem cells (MuSCs) are morphologically and functionally heterogeneous and exhibit different lengths of cellular extensions, which we call protrusions. Here, we present a protocol for ex vivo two-photon imaging of Mu
Externí odkaz:
https://doaj.org/article/4ea0ec806c384465b35167752bf1f9fe
Autor:
Elisia D. Tichy, Ji-Hyung Lee, Grant Li, Katrina N. Estep, F. Brad Johnson, Foteini Mourkioti
Publikováno v:
npj Microgravity, Vol 9, Iss 1, Pp 1-11 (2023)
Abstract Astronauts are exposed to harsh conditions, including cosmic radiation and microgravity. Spaceflight elongates human telomeres in peripheral blood, which shorten upon return to Earth and approach baseline levels during postflight recovery. A
Externí odkaz:
https://doaj.org/article/49296aaceaad41838d28e1fc4c254dfa
Publikováno v:
Biomedicines, Vol 12, Iss 4, p 779 (2024)
Fibrodysplasia ossificans progressiva (FOP) is a debilitating genetic disorder characterized by recurrent episodes of heterotopic ossification (HO) formation in muscles, tendons, and ligaments. FOP is caused by a missense mutation in the ACVR1 gene (
Externí odkaz:
https://doaj.org/article/4dcf586db7334c53b1d8132e8f5cf964
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S674- (2023)
Externí odkaz:
https://doaj.org/article/cf4597873f3445e3ae72cf2f6361b4cf
Autor:
Catherine A. Bautista, Anjana Srikumar, Elisia D. Tichy, Grace Qian, Xi Jiang, Ling Qin, Foteini Mourkioti, Nathaniel A. Dyment
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Resident macrophages exist in a variety of tissues, including tendon, and play context-specific roles in their tissue of residence. In this study, we define the spatiotemporal distribution and phenotypic profile of tendon resident macrophages and the
Externí odkaz:
https://doaj.org/article/b05cad8694914ffb864a0a39583ac6f6
Autor:
Alexandra Stanley, Elisia D. Tichy, Jacob Kocan, Douglas W. Roberts, Eileen M. Shore, Foteini Mourkioti
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-15 (2022)
Abstract Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disease in which extraskeletal (heterotopic) bone forms within tissues such as skeletal muscles, often in response to injury. Mutations in the BMP type I receptor ACVR1/ALK2 cause
Externí odkaz:
https://doaj.org/article/bcf4f99d03a14ec5b5bc0b5df6fb2cc2
Autor:
Elisia D. Tichy, Foteini Mourkioti
Publikováno v:
STAR Protocols, Vol 2, Iss 4, Pp 100830- (2021)
Summary: Measurements of telomere length in skeletal muscle stem cells (MuSCs), a rare cell population within muscles, provide insights into cellular dysfunction in diseased conditions. Here, we describe a protocol (cryosection muscle quantitative fl
Externí odkaz:
https://doaj.org/article/a4c73a2159ae49bbb4c91c7d49a12b08
Autor:
Elisia D. Tichy, David K. Sidibe, Christopher D. Greer, Nicholas M. Oyster, Panteleimon Rompolas, Nadia A. Rosenthal, Helen M. Blau, Foteini Mourkioti
Publikováno v:
Skeletal Muscle, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract Background Pax7 is a transcription factor involved in the specification and maintenance of muscle stem cells (MuSCs). Upon injury, MuSCs leave their quiescent state, downregulate Pax7 and differentiate, contributing to skeletal muscle regene
Externí odkaz:
https://doaj.org/article/27ec8e7c1d7b4772a6981532d288802e
Autor:
Elisia D. Tichy, David K. Sidibe, Matthew T. Tierney, Michael J. Stec, Maryam Sharifi-Sanjani, Harish Hosalkar, Scott Mubarak, F. Brad Johnson, Alessandra Sacco, Foteini Mourkioti
Publikováno v:
Stem Cell Reports, Vol 9, Iss 4, Pp 1328-1341 (2017)
Muscle stem cells (MuSCs) contribute to muscle regeneration following injury. In many muscle disorders, the repeated cycles of damage and repair lead to stem cell dysfunction. While telomere attrition may contribute to aberrant stem cell functions, m
Externí odkaz:
https://doaj.org/article/53d32f4122614c7e89b36de0894eaa3d