Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Fosado, Y. A. G."'
We study the effect of transcription on the kinetics of DNA supercoiling in 3D by means of Brownian dynamics simulations of a single nucleotide resolution coarse-grained model for double stranded DNA. By accounting for the action of a transcribing RN
Externí odkaz:
http://arxiv.org/abs/1906.03287
Publikováno v:
Phys. Rev. Lett. 119, 118002 (2017)
There is a long-standing experimental observation that the melting of topologically constrained DNA, such as circular-closed plasmids, is less abrupt than that of linear molecules. This finding points to an intriguing role of topology in the physics
Externí odkaz:
http://arxiv.org/abs/1703.08367
The computational modelling of DNA is becoming crucial in light of new advances in DNA nanotechnology, single-molecule experiments and in vivo DNA tampering. Here we present a mesoscopic model for double stranded DNA (dsDNA) at the single nucleotide
Externí odkaz:
http://arxiv.org/abs/1608.03722
Autor:
Fosado YA; School of Physics and Astronomy, University of Edinburgh, Peter Guthrie Tait Road, Edinburgh EH9 3FD, Scotland, UK., Michieletto D; School of Physics and Astronomy, University of Edinburgh, Peter Guthrie Tait Road, Edinburgh EH9 3FD, Scotland, UK., Allan J; Institute of Genetics and Molecular Medicine, MRC Human Genetics Unit, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK., Brackley CA; School of Physics and Astronomy, University of Edinburgh, Peter Guthrie Tait Road, Edinburgh EH9 3FD, Scotland, UK., Henrich O; School of Physics and Astronomy, University of Edinburgh, Peter Guthrie Tait Road, Edinburgh EH9 3FD, Scotland, UK and EPCC, University of Edinburgh, Peter Guthrie Tait Road, Edinburgh EH9 3FD, Scotland, UK., Marenduzzo D; School of Physics and Astronomy, University of Edinburgh, Peter Guthrie Tait Road, Edinburgh EH9 3FD, Scotland, UK.
Publikováno v:
Soft matter [Soft Matter] 2016 Nov 28; Vol. 12 (47), pp. 9458-9470.