Association of hyperactivated transposon expression with exacerbated immune activation in systemic lupus erythematosus.

Autor: Wang, Frank Qingyun¹ (AUTHOR), Dang, Xiao¹ (AUTHOR), Su, Huidong¹ (AUTHOR), Lei, Yao¹ (AUTHOR), She, Chun Hing¹ (AUTHOR), Zhang, Caicai¹ (AUTHOR), Chen, Xinxin¹ (AUTHOR), Yang, Xingtian¹ (AUTHOR), Yang, Jing¹ (AUTHOR), Feng, Hong¹ (AUTHOR), Yang, Wanling¹ (AUTHOR) yangwl@hku.hk

Publikováno v: Mobile DNA. 10/19/2024, Vol. 15 Issue 1, p1-13. 13p.

mTORC1 directly inhibits AMPK to promote cell proliferation under nutrient stress.

Autor: Ling NXY; Metabolic Signalling Laboratory, St Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Melbourne, Victoria, Australia., Kaczmarek A; Flinders Centre for Innovation in Cancer, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia., Hoque A; Metabolic Signalling Laboratory, St Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Melbourne, Victoria, Australia., Davie E; Faculty of Life Sciences, University of Manchester, Manchester, UK., Ngoei KRW; Protein Chemistry and Metabolism Unit, St Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Melbourne, Victoria, Australia., Morrison KR; Flinders Centre for Innovation in Cancer, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia., Smiles WJ; Metabolic Signalling Laboratory, St Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Melbourne, Victoria, Australia., Forte GM; Faculty of Life Sciences, University of Manchester, Manchester, UK., Wang T; Flinders Centre for Innovation in Cancer, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia., Lie S; Flinders Centre for Innovation in Cancer, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia., Dite TA; Metabolic Signalling Laboratory, St Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Melbourne, Victoria, Australia.; MRC Protein Phosphorylation and Ubiquitylation Unit, James Black Centre, University of Dundee, Dundee, UK., Langendorf CG; Protein Chemistry and Metabolism Unit, St Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Melbourne, Victoria, Australia., Scott JW; Protein Chemistry and Metabolism Unit, St Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Melbourne, Victoria, Australia.; Mary MacKillop Institute for Health Research, Australian Catholic University, Melbourne, Victoria, Australia.; Florey Institute of Neuroscience and Mental Health, Parkville, Victoria, Australia., Oakhill JS; Metabolic Signalling Laboratory, St Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Melbourne, Victoria, Australia. joakhill@svi.edu.au.; Mary MacKillop Institute for Health Research, Australian Catholic University, Melbourne, Victoria, Australia. joakhill@svi.edu.au., Petersen J; Flinders Centre for Innovation in Cancer, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia. janni.petersen@flinders.edu.au.; Faculty of Life Sciences, University of Manchester, Manchester, UK. janni.petersen@flinders.edu.au.; Nutrition and Metabolism, South Australia Health and Medical Research Institute, Adelaide, South Australia, Australia. janni.petersen@flinders.edu.au.

Publikováno v: Nature metabolism [Nat Metab] 2020 Jan; Vol. 2 (1), pp. 41-49. Date of Electronic Publication: 2020 Jan 20.

Gain of function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling

Autor: Rice, Gi, Del Toro Duany, Y, Jenkinson, Em, Forte, Gm, Anderson, Bh, Ariaudo, G, Bader-Meunier, B, Baildm, Em, Battini, R, Beresford, Mw, Casarano, M, Chouchane, M, Cimaz, R, Collins, Ae, Cordeiro, Nj, Dale, Rc, Davidson, Je, Waelel, De, Desguerre, I, Faivre, L, Fazzi, E, Isidor, B, Lagae, L, Larchman, Ar, Lebon, P, Li, C, Livingston, Jh, Lourenço, Cm, Mancardi, Mm, Masurel-Paulet, A, Mcinnes, Ib, Menezes, Mp, Mignot, C, O'Sullivan, J, Orcesi, S, Picco, Pp, Riva, E, Robinson, Ra, Rodriguez, D, Salvatici, E, Scott, C, Szybowska, M, Tolmie, Jl, Vanderver, A, Vanhulle, C, Vieira, Jp, Webb, K, Whitney, Rn, Williams, Sg, Wolfe, La, Zuberi, Sm, Hur, S, Crow, Yj

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3728::6511a69cdd6ee2ca56e9c531cb27d106
http://hdl.handle.net/11568/951205

Import of extracellular ATP in yeast and man modulates AMPK and TORC1 signalling.

Autor: Forte GM; Faculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester, M13 9PT, United Kingdom., Davie E; Faculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester, M13 9PT, United Kingdom., Lie S; Flinders Centre for Innovation in Cancer, College of Medicine & Public health, Flinders University, Adelaide, SA 5001, Australia., Franz-Wachtel M; Proteome Center Tuebingen, University of Tuebingen, Auf der Morgenstelle 15, 72076 Tuebingen, Germany., Ovens AJ; Metabolic Signalling Laboratory, St Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Victoria 3065, Australia.; Mary MacKillop Institute for Health Research, Australian Catholic University, Victoria 3000, Australia., Wang T; Flinders Centre for Innovation in Cancer, College of Medicine & Public health, Flinders University, Adelaide, SA 5001, Australia., Oakhill JS; Metabolic Signalling Laboratory, St Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Victoria 3065, Australia.; Mary MacKillop Institute for Health Research, Australian Catholic University, Victoria 3000, Australia., Maček B; Proteome Center Tuebingen, University of Tuebingen, Auf der Morgenstelle 15, 72076 Tuebingen, Germany., Hagan IM; Cancer Research UK Manchester institute, Alderley Park, Macclesfield SK10 4TG, United Kingdom., Petersen J; Faculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester, M13 9PT, United Kingdom janni.petersen@flinders.edu.au.; Flinders Centre for Innovation in Cancer, College of Medicine & Public health, Flinders University, Adelaide, SA 5001, Australia.; South Australia Health and Medical Research Institute, North Terrace, PO Box 11060, Adelaide SA 5000 Australia.

Publikováno v: Journal of cell science [J Cell Sci] 2019 Apr 03; Vol. 132 (7). Date of Electronic Publication: 2019 Apr 03.

Brain-targeted stem cell gene therapy corrects mucopolysaccharidosis type II via multiple mechanisms.

Autor: Gleitz HF; Stem Cell and Neurotherapies, Division of Cell Matrix Biology & Regenerative Medicine, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK., Liao AY; Stem Cell and Neurotherapies, Division of Cell Matrix Biology & Regenerative Medicine, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK., Cook JR; Stem Cell and Neurotherapies, Division of Cell Matrix Biology & Regenerative Medicine, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK., Rowlston SF; Stem Cell and Neurotherapies, Division of Cell Matrix Biology & Regenerative Medicine, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK., Forte GM; Stem Cell and Neurotherapies, Division of Cell Matrix Biology & Regenerative Medicine, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK., D'Souza Z; Stem Cell and Neurotherapies, Division of Cell Matrix Biology & Regenerative Medicine, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK., O'Leary C; Stem Cell and Neurotherapies, Division of Cell Matrix Biology & Regenerative Medicine, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK., Holley RJ; Stem Cell and Neurotherapies, Division of Cell Matrix Biology & Regenerative Medicine, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK., Bigger BW; Stem Cell and Neurotherapies, Division of Cell Matrix Biology & Regenerative Medicine, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK brian.bigger@manchester.ac.uk.

Publikováno v: EMBO molecular medicine [EMBO Mol Med] 2018 Jul; Vol. 10 (7).