Pharmacokinetics of Cefuroxime in Cortical and Cancellous Bone Obtained by Microdialysis - a Porcine Study

Autor: Tøttrup, Mikkel, Forsingdal Hardlei, Tore, Bendtsen, Michael, Bue, Mats, Brock, Birgitte, Fuursted, Kurt, Søballe, Kjeld, Birke-Sørensen, Hanne

Publikováno v: Tøttrup, M, Forsingdal Hardlei, T, Bendtsen, M, Bue, M, Brock, B, Fuursted, K, Søballe, K & Birke-Sørensen, H 2014, ' Pharmacokinetics of Cefuroxime in Cortical and Cancellous Bone Obtained by Microdialysis-a Porcine Study ', Antimicrobial Agents and Chemotherapy, vol. 58, no. 6, pp. 3200-3205 . https://doi.org/10.1128/AAC.02438-14

Traditionally, the pharmacokinetics of antimicrobials in bone have been investigated using bone biopsies, but this approach suffers from considerable methodological limitations. Consequently, new methods are needed. The objectives of this study were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pure_au_____::45c2cfb442514aab7a9bfe8b0bbd8b11
https://pure.au.dk/portal/da/publications/pharmacokinetics-of-cefuroxime-in-cortical-and-cancellous-bone-obtained-by-microdialysis--a-porcine-study(3e20a1c1-8058-4d4a-9a3b-bc490632967f).html