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Autor:
Forsdyke, Donald R.
Tropical climates provoke adaptations in skin pigmentation and in mechanisms controlling the volume, salt-content and pressure of body fluids. For many whose distant ancestors moved to temperate climes, these adaptations proved harmful: pigmentation
Externí odkaz:
http://arxiv.org/abs/2005.01579
Autor:
Forsdyke, Donald R.
The utility of DNA sequence substrings (k-mers) in alignment-free phylogenetic classification, including that of bacteria and viruses, is increasingly recognized. However, its biological basis eludes many twenty-first century practitioners. A path fr
Externí odkaz:
http://arxiv.org/abs/1903.04866
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Autor:
Forsdyke, Donald R.
Whether a sub-optimum lymphocyte stimulus is achieved by lowering ligand concentration, or decreasing its affinity, initial TCR activation responses are likely to be digital. We now know for cultured peripheral blood mononuclear cells (PBMCs), when a
Externí odkaz:
http://arxiv.org/abs/1809.02866
Autor:
Forsdyke, Donald R.
Recent writings on "innate immune memory" or "trained immunity," and on "hormetic responses," herald reinvigoration of an important research area with early 20th century roots. However, it is questionable that the thesis of a "major importance of the
Externí odkaz:
http://arxiv.org/abs/1807.08353