Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Forschungszentren » Zentrum für Medizinische Biotechnologie (ZMB)"'
Autor:
Lisa Oelschläger, Paul Stahl, Farnusch Kaschani, Roland H. Stauber, Shirley K. Knauer, Astrid Hensel
Publikováno v:
Cells
Volume 12
Issue 3
Pages: 363
Volume 12
Issue 3
Pages: 363
OA Förderung 2023 The human protease Taspase1 plays a pivotal role in developmental processes and cancerous diseases by processing critical regulators, such as the leukemia proto-oncoprotein MLL. Despite almost two decades of intense research, Taspa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99210f97d3b5ebfd2d7b9f875ae78815
https://www.ncbi.nlm.nih.gov/pubmed/36766705
https://www.ncbi.nlm.nih.gov/pubmed/36766705
Autor:
Dagny Holle, Stefan Zuelow, Hans-Christoph-Diener, Christoph Kleinschnitz, Christopher Michael Weise, Mark Obermann, K. Solbach, Anders Hougard, Julia Zeller, Steffen Naegel
Publikováno v:
Cephalalgia. 42:335-344
Objective To identify grey matter alterations in patients suffering new daily persistent headache to enrich the pathophysiological concept of this rare headache disorder characterised by a distinct, clearly remembered onset and its instant chronifica
The initiation step of replication at replication origins determines when and where in the genome replication machines, replisomes, are generated. Tight control of replication initiation helps facilitate the two main tasks of genome replication, to d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0af0a2796bb8a1c52198912d2f9763a9
https://duepublico2.uni-due.de/receive/duepublico_mods_00076617
https://duepublico2.uni-due.de/receive/duepublico_mods_00076617
Autor:
Thomas Klaus, Sabrina Ninck, Andreas Albersmeier, Tobias Busche, Daniel Wibberg, Jianbing Jiang, Alexander G. Elcheninov, Kseniya S. Zayulina, Farnusch Kaschani, Christopher Bräsen, Herman S. Overkleeft, Jörn Kalinowski, Ilya V. Kublanov, Markus Kaiser, Bettina Siebers
Publikováno v:
Frontiers in Microbiology
Frontiers in Microbiology, 12:734039
Frontiers in Microbiology, Vol 12 (2022)
Frontiers in Microbiology, 12:734039
Frontiers in Microbiology, Vol 12 (2022)
Activity-based protein profiling (ABPP) has so far scarcely been applied in Archaea in general and, especially, in extremophilic organisms. We herein isolated a novel Thermococcus strain designated sp. strain 2319x1E derived from the same enrichment
Autor:
Astrid Hensel, Paul Stahl, Lisa Moews, Lena König, Rutuja Patwardhan, Alexander Höing, Nina Schulze, Perihan Nalbant, Roland H. Stauber, Shirley K. Knauer
Publikováno v:
iScience. 25(6)
OA Förderung 2022 The unique threonine protease Tasp1 impacts not only ordered development and cell proliferation but also pathologies. However, its substrates and the underlying molecular mechanisms remain poorly understood. We demonstrate that the
Publikováno v:
Molecules, Vol 25, Iss 5466, p 5466 (2020)
Molecules
Molecules (Basel, Switzerland), vol 25, iss 23
Molecules
Molecules (Basel, Switzerland), vol 25, iss 23
Since the pioneering work of Ned Seeman in the early 1980s, the use of the DNA molecule as a construction material experienced a rapid growth and led to the establishment of a new field of science, nowadays called structural DNA nanotechnology. Here,
Autor:
Simone Hohoff, Peter Bayer, Miriam Böhm, Karolin Jänen, Kerstin Killinger, Mike Blüggel, Philine Steinbach, Franz Herzog, Götz Hagemann, Stefan Westermann
Publikováno v:
The EMBO Journal
Kinetochores are chromatin‐bound multi‐protein complexes that allow high‐fidelity chromosome segregation during mitosis and meiosis. Kinetochore assembly is exclusively initiated at chromatin containing Cse4/CENP‐A nucleosomes. The molecular
Autor:
Yingying Cao, Qian Li, Yingying Zhang, Yongmei Yin, Yuanwang Qiu, Mengji Lu, Xiaoming Lin, Lihua Huang, Daniel Hoffmann, Jun Wang
Publikováno v:
Frontiers in Immunology
Background: Cases of excessive neutrophil counts in the blood in severe coronavirus disease (COVID-19) patients have drawn significant attention. Neutrophil infiltration was also noted on the pathological findings from autopsy. It is urgent to clarif
Autor:
Martin Metzenmacher, Renáta Váraljai, Balazs Hegedüs, Igor Cima, Jan Forster, Alexander Schramm, Björn Scheffler, Peter A. Horn, Christoph A. Klein, Tibor Szarvas, Hennig Reis, Nicola Bielefeld, Alexander Roesch, Clemens Aigner, Volker Kunzmann, Marcel Wiesweg, Jens T. Siveke, Martin Schuler, Smiths S. Lueong
Publikováno v:
Cancers
Cancers, Vol 12, Iss 2, p 353 (2020)
Cancers, Vol 12, Iss 2, p 353 (2020)
Early detection of cancer holds high promise for reducing cancer-related mortality. Detection of circulating tumor-specific nucleic acids holds promise, but sensitivity and specificity issues remain with current technology. We studied cell-free RNA (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b679b8deffd14d162c35207b3d25243c
https://publica.fraunhofer.de/handle/publica/262151
https://publica.fraunhofer.de/handle/publica/262151
Publikováno v:
Biomolecules
Volume 9
Issue 12
Volume 9
Issue 12
AAA+ ATPase p97/valosin-containing protein (VCP)/Cdc48 is a key player in various cellular stress responses in which it unfolds ubiquitinated proteins to facilitate their degradation by the proteasome. P97 works in different cellular processes using