Evaluation of the immune-modulatory, anti-oxidant, proliferative, and anti-apoptotic effects of nano-silymarin on mesenchymal stem cells isolated from multiple sclerosis patients' adipose tissue sources

Autor: Fahimeh Lavi Arab, Forouzan Yousefi, Mahmoud Reza Jaafari, Arezoo Rajabian, Hassan Dana, Nafiseh Tabasi, Saeed Behboodifar, Arezoo Faridzadeh, Mahmoud Mahmoudi

Publikováno v: Journal of Functional Foods, Vol 113, Iss , Pp 105958- (2024)

Silymarin (SL) has a long history of use for the treatment of a variety of diseases, but several limitations, such as poor bioavailability and negligible solubility, have restricted its successful translation in a clinical setting. However, the nano-

Externí odkaz: https://doaj.org/article/362d7d32d0c74144b3cc13e11dcf13c4

Various strategies to improve efficacy of stem cell transplantation in multiple sclerosis: Focus on mesenchymal stem cells and neuroprotection

Autor: Mahmoud Mahmoudi, Kolsoum Saeidi, Houshang Amiri, Forouzan Yousefi, Fahimeh Lavi Arab

Publikováno v: Yousefi, F, Lavi Arab, F, Saeidi, K, Amiri, H & Mahmoudi, M 2019, ' Various strategies to improve efficacy of stem cell transplantation in multiple sclerosis: Focus on mesenchymal stem cells and neuroprotection ', Journal of Neuroimmunology, vol. 328, pp. 20-34 . https://doi.org/10.1016/j.jneuroim.2018.11.015

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS) which predominantly affect young adults and undergo heavy socioeconomic burdens. Conventional therapeutic modalities for MS mostly downregulate aggre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e994cff026a9c68b891423429e109749
https://pubmed.ncbi.nlm.nih.gov/30557687

In vivo immunomodulatory effects of adipose-derived mesenchymal stem cells conditioned medium in experimental autoimmune encephalomyelitis

Autor: Sara Soudi, Forouzan Yousefi, Masoud Soleimani, Seyed Mahmoud Hashemi, Massoumeh Ebtekar

Publikováno v: Immunology letters. 172

Mesenchymal stem cells (MSCs) are well known to possess neuroprotective and immunomodulatory effects, due to cell-to-cell interaction and their soluble factors. We conducted a comparative analysis of the immunomodulatory properties of adipose tissue

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da0b6155aca16ac84a98309e3f4ecb39
https://pubmed.ncbi.nlm.nih.gov/26930038