Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Foroozan Mokhtarian"'
Publikováno v:
Brain Research. 1236:206-215
Axonal injury is the major correlate of permanent disability in neurodegenerative diseases such as multiple sclerosis (MS), especially in secondary-progressive MS which follows relapsing-remitting disease course. Proteolytic enzyme, calpain, is a pot
Publikováno v:
Journal of Neuroimmunology. 137:19-31
Semliki Forest virus (SFV) infection induces a demyelinating encephalomyelitis in the central nervous system (CNS) of mice and serves as a model for multiple sclerosis (MS). This study investigated CNS immune responses at different stages of infectio
Publikováno v:
Journal of Laboratory and Clinical Medicine. 138:112-118
This study sought to investigate the interplay between antibody and T cell responses triggered by an acute myocardial infarction (MI) and their possible role in the progress of this disease. Serum samples were collected from two groups of patients, g
Publikováno v:
Journal of Neuroimmunology. 95:43-54
Semliki Forest Virus (SFV) induces an encephalomyelitis followed by demyelination in the brains of C57Bl6/J (B6) mice. To investigate the role of molecular mimicry in the pathogenesis of postviral demyelination, alignment algorithms were used and ami
Autor:
Foroozan Mokhtarian
Publikováno v:
Journal of Neurological Disorders.
Multiple sclerosis is an inflammatory autoimmune-mediated disease of the Central Nervous System (CNS). Different treatment protocols, based on neurotropic viral infections and/or immunization with CNS proteins, have been implemented. Although there a
Autor:
David Grob, Foroozan Mokhtarian, Diane E. Griffin, Steven Choi, Raymond A. Sobel, Steven Lodewyk Wesselingh, Atsuko Maeda
Publikováno v:
Journal of Neuroimmunology. 66:11-22
Semliki Forest Virus (SFV) causes a more severe acute encephalomyelitis in B6 than in SJL mice despite similar T cell proliferation and antibody responses in these two strains. To determine the immunological mechanisms that may contribute to this dif
Publikováno v:
Brain research. 1488
Remyelination is one of the elusive topics in treatment of multiple sclerosis (MS). Our previous studies have shown that Semliki Forest virus (SFV)-infected δ-knock-out (KO) mice did not exhibit the extensive remyelination, seen in wild type (WT) B6
Publikováno v:
Cellular Immunology. 157:195-210
A combined role of a virus infection of the central nervous system (CNS) and an autoimmune response to myelin basic protein (MBP), an autoantigen of the CNS, is suggested in the pathogenesis of multiple sclerosis (MS). SJL mice are highly susceptible
Publikováno v:
Journal of neuroimmunology. 235(1-2)
Semliki Forest Virus (SFV) encephalomyelitis has been used to study the pathogenesis of virus-induced demyelination and serves as a model for multiple sclerosis. SFV-infection of mice invariably leads to clinical weakness accompanied by CNS inflammat
Autor:
David Grob, Giuseppe Spatoliatore, Barry C. Herzlich, Djamshid Shirazian, Foroozan Mokhtarian
Publikováno v:
American Journal of Infection Control. 20:133-137
Introduction: Because transmission of HIV to health care workers after needlestick injury has occurred mainly a result of deep insertion of large gauge needles, blood and viable mononuclear cells transferred after needlestick injury were measured. Me