StrainNet: Improved Myocardial Strain Analysis of Cine MRI by Deep Learning from DENSE.

Autor: Wang Y; From the Department of Biomedical Engineering, University of Virginia, Biomedical Engineering and Medical Science Building, Room 2013, MR5, Charlottesville, VA 22903 (Y.W., C.S., S.G., D.C.A., F.H.E.); Department of Biomedical, Biological and Chemical Engineering and Department of Radiology, University of Missouri, Columbia, Mo (C.S.); Department of Radiology, University Hospital of Saint Etienne, Saint Etienne, France (P.C.); CREATIS (UMR CNRS 5220, U1206 INSERM), INSA Lyon, Lyon, France (P.C., M.V.); BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, Scotland (K.M., C.B.); Department of Translational Data Science and Informatics, Geisinger Health System, Danville, Pa (C.M.H., L.J., B.K.F.); Cardiovascular Research Center, University of Kentucky, Lexington, Ky (C.M.H., L.J., B.K.F.); The Heart Center, St Francis Hospital, Roslyn, NY (J.J.C., J.C.); Cardiovascular Magnetic Resonance Unit, The Royal Brompton Hospital and National Heart and Lung Institute, Imperial College London, London, England (A.D.S., P.F.F.); Department of Radiology & Imaging Sciences and Biomedical Engineering, Emory University, Atlanta, Ga (J.N.O.); Department of Radiology, Stanford University, Stanford, Calif (D.B.E.); Department of Medicine (K.C.B.) and Department of Radiology and Medical Imaging (F.H.E.), University of Virginia Health System, Charlottesville, Va., Sun C; From the Department of Biomedical Engineering, University of Virginia, Biomedical Engineering and Medical Science Building, Room 2013, MR5, Charlottesville, VA 22903 (Y.W., C.S., S.G., D.C.A., F.H.E.); Department of Biomedical, Biological and Chemical Engineering and Department of Radiology, University of Missouri, Columbia, Mo (C.S.); Department of Radiology, University Hospital of Saint Etienne, Saint Etienne, France (P.C.); CREATIS (UMR CNRS 5220, U1206 INSERM), INSA Lyon, Lyon, France (P.C., M.V.); BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, Scotland (K.M., C.B.); Department of Translational Data Science and Informatics, Geisinger Health System, Danville, Pa (C.M.H., L.J., B.K.F.); Cardiovascular Research Center, University of Kentucky, Lexington, Ky (C.M.H., L.J., B.K.F.); The Heart Center, St Francis Hospital, Roslyn, NY (J.J.C., J.C.); Cardiovascular Magnetic Resonance Unit, The Royal Brompton Hospital and National Heart and Lung Institute, Imperial College London, London, England (A.D.S., P.F.F.); Department of Radiology & Imaging Sciences and Biomedical Engineering, Emory University, Atlanta, Ga (J.N.O.); Department of Radiology, Stanford University, Stanford, Calif (D.B.E.); Department of Medicine (K.C.B.) and Department of Radiology and Medical Imaging (F.H.E.), University of Virginia Health System, Charlottesville, Va., Ghadimi S; From the Department of Biomedical Engineering, University of Virginia, Biomedical Engineering and Medical Science Building, Room 2013, MR5, Charlottesville, VA 22903 (Y.W., C.S., S.G., D.C.A., F.H.E.); Department of Biomedical, Biological and Chemical Engineering and Department of Radiology, University of Missouri, Columbia, Mo (C.S.); Department of Radiology, University Hospital of Saint Etienne, Saint Etienne, France (P.C.); CREATIS (UMR CNRS 5220, U1206 INSERM), INSA Lyon, Lyon, France (P.C., M.V.); BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, Scotland (K.M., C.B.); Department of Translational Data Science and Informatics, Geisinger Health System, Danville, Pa (C.M.H., L.J., B.K.F.); Cardiovascular Research Center, University of Kentucky, Lexington, Ky (C.M.H., L.J., B.K.F.); The Heart Center, St Francis Hospital, Roslyn, NY (J.J.C., J.C.); Cardiovascular Magnetic Resonance Unit, The Royal Brompton Hospital and National Heart and Lung Institute, Imperial College London, London, England (A.D.S., P.F.F.); Department of Radiology & Imaging Sciences and Biomedical Engineering, Emory University, Atlanta, Ga (J.N.O.); Department of Radiology, Stanford University, Stanford, Calif (D.B.E.); Department of Medicine (K.C.B.) and Department of Radiology and Medical Imaging (F.H.E.), University of Virginia Health System, Charlottesville, Va., Auger DC; From the Department of Biomedical Engineering, University of Virginia, Biomedical Engineering and Medical Science Building, Room 2013, MR5, Charlottesville, VA 22903 (Y.W., C.S., S.G., D.C.A., F.H.E.); Department of Biomedical, Biological and Chemical Engineering and Department of Radiology, University of Missouri, Columbia, Mo (C.S.); Department of Radiology, University Hospital of Saint Etienne, Saint Etienne, France (P.C.); CREATIS (UMR CNRS 5220, U1206 INSERM), INSA Lyon, Lyon, France (P.C., M.V.); BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, Scotland (K.M., C.B.); Department of Translational Data Science and Informatics, Geisinger Health System, Danville, Pa (C.M.H., L.J., B.K.F.); Cardiovascular Research Center, University of Kentucky, Lexington, Ky (C.M.H., L.J., B.K.F.); The Heart Center, St Francis Hospital, Roslyn, NY (J.J.C., J.C.); Cardiovascular Magnetic Resonance Unit, The Royal Brompton Hospital and National Heart and Lung Institute, Imperial College London, London, England (A.D.S., P.F.F.); Department of Radiology & Imaging Sciences and Biomedical Engineering, Emory University, Atlanta, Ga (J.N.O.); Department of Radiology, Stanford University, Stanford, Calif (D.B.E.); Department of Medicine (K.C.B.) and Department of Radiology and Medical Imaging (F.H.E.), University of Virginia Health System, Charlottesville, Va., Croisille P; From the Department of Biomedical Engineering, University of Virginia, Biomedical Engineering and Medical Science Building, Room 2013, MR5, Charlottesville, VA 22903 (Y.W., C.S., S.G., D.C.A., F.H.E.); Department of Biomedical, Biological and Chemical Engineering and Department of Radiology, University of Missouri, Columbia, Mo (C.S.); Department of Radiology, University Hospital of Saint Etienne, Saint Etienne, France (P.C.); CREATIS (UMR CNRS 5220, U1206 INSERM), INSA Lyon, Lyon, France (P.C., M.V.); BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, Scotland (K.M., C.B.); Department of Translational Data Science and Informatics, Geisinger Health System, Danville, Pa (C.M.H., L.J., B.K.F.); Cardiovascular Research Center, University of Kentucky, Lexington, Ky (C.M.H., L.J., B.K.F.); The Heart Center, St Francis Hospital, Roslyn, NY (J.J.C., J.C.); Cardiovascular Magnetic Resonance Unit, The Royal Brompton Hospital and National Heart and Lung Institute, Imperial College London, London, England (A.D.S., P.F.F.); Department of Radiology & Imaging Sciences and Biomedical Engineering, Emory University, Atlanta, Ga (J.N.O.); Department of Radiology, Stanford University, Stanford, Calif (D.B.E.); Department of Medicine (K.C.B.) and Department of Radiology and Medical Imaging (F.H.E.), University of Virginia Health System, Charlottesville, Va., Viallon M; From the Department of Biomedical Engineering, University of Virginia, Biomedical Engineering and Medical Science Building, Room 2013, MR5, Charlottesville, VA 22903 (Y.W., C.S., S.G., D.C.A., F.H.E.); Department of Biomedical, Biological and Chemical Engineering and Department of Radiology, University of Missouri, Columbia, Mo (C.S.); Department of Radiology, University Hospital of Saint Etienne, Saint Etienne, France (P.C.); CREATIS (UMR CNRS 5220, U1206 INSERM), INSA Lyon, Lyon, France (P.C., M.V.); BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, Scotland (K.M., C.B.); Department of Translational Data Science and Informatics, Geisinger Health System, Danville, Pa (C.M.H., L.J., B.K.F.); Cardiovascular Research Center, University of Kentucky, Lexington, Ky (C.M.H., L.J., B.K.F.); The Heart Center, St Francis Hospital, Roslyn, NY (J.J.C., J.C.); Cardiovascular Magnetic Resonance Unit, The Royal Brompton Hospital and National Heart and Lung Institute, Imperial College London, London, England (A.D.S., P.F.F.); Department of Radiology & Imaging Sciences and Biomedical Engineering, Emory University, Atlanta, Ga (J.N.O.); Department of Radiology, Stanford University, Stanford, Calif (D.B.E.); Department of Medicine (K.C.B.) and Department of Radiology and Medical Imaging (F.H.E.), University of Virginia Health System, Charlottesville, Va., Mangion K; From the Department of Biomedical Engineering, University of Virginia, Biomedical Engineering and Medical Science Building, Room 2013, MR5, Charlottesville, VA 22903 (Y.W., C.S., S.G., D.C.A., F.H.E.); Department of Biomedical, Biological and Chemical Engineering and Department of Radiology, University of Missouri, Columbia, Mo (C.S.); Department of Radiology, University Hospital of Saint Etienne, Saint Etienne, France (P.C.); CREATIS (UMR CNRS 5220, U1206 INSERM), INSA Lyon, Lyon, France (P.C., M.V.); BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, Scotland (K.M., C.B.); Department of Translational Data Science and Informatics, Geisinger Health System, Danville, Pa (C.M.H., L.J., B.K.F.); Cardiovascular Research Center, University of Kentucky, Lexington, Ky (C.M.H., L.J., B.K.F.); The Heart Center, St Francis Hospital, Roslyn, NY (J.J.C., J.C.); Cardiovascular Magnetic Resonance Unit, The Royal Brompton Hospital and National Heart and Lung Institute, Imperial College London, London, England (A.D.S., P.F.F.); Department of Radiology & Imaging Sciences and Biomedical Engineering, Emory University, Atlanta, Ga (J.N.O.); Department of Radiology, Stanford University, Stanford, Calif (D.B.E.); Department of Medicine (K.C.B.) and Department of Radiology and Medical Imaging (F.H.E.), University of Virginia Health System, Charlottesville, Va., Berry C; From the Department of Biomedical Engineering, University of Virginia, Biomedical Engineering and Medical Science Building, Room 2013, MR5, Charlottesville, VA 22903 (Y.W., C.S., S.G., D.C.A., F.H.E.); Department of Biomedical, Biological and Chemical Engineering and Department of Radiology, University of Missouri, Columbia, Mo (C.S.); Department of Radiology, University Hospital of Saint Etienne, Saint Etienne, France (P.C.); CREATIS (UMR CNRS 5220, U1206 INSERM), INSA Lyon, Lyon, France (P.C., M.V.); BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, Scotland (K.M., C.B.); Department of Translational Data Science and Informatics, Geisinger Health System, Danville, Pa (C.M.H., L.J., B.K.F.); Cardiovascular Research Center, University of Kentucky, Lexington, Ky (C.M.H., L.J., B.K.F.); The Heart Center, St Francis Hospital, Roslyn, NY (J.J.C., J.C.); Cardiovascular Magnetic Resonance Unit, The Royal Brompton Hospital and National Heart and Lung Institute, Imperial College London, London, England (A.D.S., P.F.F.); Department of Radiology & Imaging Sciences and Biomedical Engineering, Emory University, Atlanta, Ga (J.N.O.); Department of Radiology, Stanford University, Stanford, Calif (D.B.E.); Department of Medicine (K.C.B.) and Department of Radiology and Medical Imaging (F.H.E.), University of Virginia Health System, Charlottesville, Va., Haggerty CM; From the Department of Biomedical Engineering, University of Virginia, Biomedical Engineering and Medical Science Building, Room 2013, MR5, Charlottesville, VA 22903 (Y.W., C.S., S.G., D.C.A., F.H.E.); Department of Biomedical, Biological and Chemical Engineering and Department of Radiology, University of Missouri, Columbia, Mo (C.S.); Department of Radiology, University Hospital of Saint Etienne, Saint Etienne, France (P.C.); CREATIS (UMR CNRS 5220, U1206 INSERM), INSA Lyon, Lyon, France (P.C., M.V.); BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, Scotland (K.M., C.B.); Department of Translational Data Science and Informatics, Geisinger Health System, Danville, Pa (C.M.H., L.J., B.K.F.); Cardiovascular Research Center, University of Kentucky, Lexington, Ky (C.M.H., L.J., B.K.F.); The Heart Center, St Francis Hospital, Roslyn, NY (J.J.C., J.C.); Cardiovascular Magnetic Resonance Unit, The Royal Brompton Hospital and National Heart and Lung Institute, Imperial College London, London, England (A.D.S., P.F.F.); Department of Radiology & Imaging Sciences and Biomedical Engineering, Emory University, Atlanta, Ga (J.N.O.); Department of Radiology, Stanford University, Stanford, Calif (D.B.E.); Department of Medicine (K.C.B.) and Department of Radiology and Medical Imaging (F.H.E.), University of Virginia Health System, Charlottesville, Va., Jing L; From the Department of Biomedical Engineering, University of Virginia, Biomedical Engineering and Medical Science Building, Room 2013, MR5, Charlottesville, VA 22903 (Y.W., C.S., S.G., D.C.A., F.H.E.); Department of Biomedical, Biological and Chemical Engineering and Department of Radiology, University of Missouri, Columbia, Mo (C.S.); Department of Radiology, University Hospital of Saint Etienne, Saint Etienne, France (P.C.); CREATIS (UMR CNRS 5220, U1206 INSERM), INSA Lyon, Lyon, France (P.C., M.V.); BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, Scotland (K.M., C.B.); Department of Translational Data Science and Informatics, Geisinger Health System, Danville, Pa (C.M.H., L.J., B.K.F.); Cardiovascular Research Center, University of Kentucky, Lexington, Ky (C.M.H., L.J., B.K.F.); The Heart Center, St Francis Hospital, Roslyn, NY (J.J.C., J.C.); Cardiovascular Magnetic Resonance Unit, The Royal Brompton Hospital and National Heart and Lung Institute, Imperial College London, London, England (A.D.S., P.F.F.); Department of Radiology & Imaging Sciences and Biomedical Engineering, Emory University, Atlanta, Ga (J.N.O.); Department of Radiology, Stanford University, Stanford, Calif (D.B.E.); Department of Medicine (K.C.B.) and Department of Radiology and Medical Imaging (F.H.E.), University of Virginia Health System, Charlottesville, Va., Fornwalt BK; From the Department of Biomedical Engineering, University of Virginia, Biomedical Engineering and Medical Science Building, Room 2013, MR5, Charlottesville, VA 22903 (Y.W., C.S., S.G., D.C.A., F.H.E.); Department of Biomedical, Biological and Chemical Engineering and Department of Radiology, University of Missouri, Columbia, Mo (C.S.); Department of Radiology, University Hospital of Saint Etienne, Saint Etienne, France (P.C.); CREATIS (UMR CNRS 5220, U1206 INSERM), INSA Lyon, Lyon, France (P.C., M.V.); BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, Scotland (K.M., C.B.); Department of Translational Data Science and Informatics, Geisinger Health System, Danville, Pa (C.M.H., L.J., B.K.F.); Cardiovascular Research Center, University of Kentucky, Lexington, Ky (C.M.H., L.J., B.K.F.); The Heart Center, St Francis Hospital, Roslyn, NY (J.J.C., J.C.); Cardiovascular Magnetic Resonance Unit, The Royal Brompton Hospital and National Heart and Lung Institute, Imperial College London, London, England (A.D.S., P.F.F.); Department of Radiology & Imaging Sciences and Biomedical Engineering, Emory University, Atlanta, Ga (J.N.O.); Department of Radiology, Stanford University, Stanford, Calif (D.B.E.); Department of Medicine (K.C.B.) and Department of Radiology and Medical Imaging (F.H.E.), University of Virginia Health System, Charlottesville, Va., Cao JJ; From the Department of Biomedical Engineering, University of Virginia, Biomedical Engineering and Medical Science Building, Room 2013, MR5, Charlottesville, VA 22903 (Y.W., C.S., S.G., D.C.A., F.H.E.); Department of Biomedical, Biological and Chemical Engineering and Department of Radiology, University of Missouri, Columbia, Mo (C.S.); Department of Radiology, University Hospital of Saint Etienne, Saint Etienne, France (P.C.); CREATIS (UMR CNRS 5220, U1206 INSERM), INSA Lyon, Lyon, France (P.C., M.V.); BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, Scotland (K.M., C.B.); Department of Translational Data Science and Informatics, Geisinger Health System, Danville, Pa (C.M.H., L.J., B.K.F.); Cardiovascular Research Center, University of Kentucky, Lexington, Ky (C.M.H., L.J., B.K.F.); The Heart Center, St Francis Hospital, Roslyn, NY (J.J.C., J.C.); Cardiovascular Magnetic Resonance Unit, The Royal Brompton Hospital and National Heart and Lung Institute, Imperial College London, London, England (A.D.S., P.F.F.); Department of Radiology & Imaging Sciences and Biomedical Engineering, Emory University, Atlanta, Ga (J.N.O.); Department of Radiology, Stanford University, Stanford, Calif (D.B.E.); Department of Medicine (K.C.B.) and Department of Radiology and Medical Imaging (F.H.E.), University of Virginia Health System, Charlottesville, Va., Cheng J; From the Department of Biomedical Engineering, University of Virginia, Biomedical Engineering and Medical Science Building, Room 2013, MR5, Charlottesville, VA 22903 (Y.W., C.S., S.G., D.C.A., F.H.E.); Department of Biomedical, Biological and Chemical Engineering and Department of Radiology, University of Missouri, Columbia, Mo (C.S.); Department of Radiology, University Hospital of Saint Etienne, Saint Etienne, France (P.C.); CREATIS (UMR CNRS 5220, U1206 INSERM), INSA Lyon, Lyon, France (P.C., M.V.); BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, Scotland (K.M., C.B.); Department of Translational Data Science and Informatics, Geisinger Health System, Danville, Pa (C.M.H., L.J., B.K.F.); Cardiovascular Research Center, University of Kentucky, Lexington, Ky (C.M.H., L.J., B.K.F.); The Heart Center, St Francis Hospital, Roslyn, NY (J.J.C., J.C.); Cardiovascular Magnetic Resonance Unit, The Royal Brompton Hospital and National Heart and Lung Institute, Imperial College London, London, England (A.D.S., P.F.F.); Department of Radiology & Imaging Sciences and Biomedical Engineering, Emory University, Atlanta, Ga (J.N.O.); Department of Radiology, Stanford University, Stanford, Calif (D.B.E.); Department of Medicine (K.C.B.) and Department of Radiology and Medical Imaging (F.H.E.), University of Virginia Health System, Charlottesville, Va., Scott AD; From the Department of Biomedical Engineering, University of Virginia, Biomedical Engineering and Medical Science Building, Room 2013, MR5, Charlottesville, VA 22903 (Y.W., C.S., S.G., D.C.A., F.H.E.); Department of Biomedical, Biological and Chemical Engineering and Department of Radiology, University of Missouri, Columbia, Mo (C.S.); Department of Radiology, University Hospital of Saint Etienne, Saint Etienne, France (P.C.); CREATIS (UMR CNRS 5220, U1206 INSERM), INSA Lyon, Lyon, France (P.C., M.V.); BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, Scotland (K.M., C.B.); Department of Translational Data Science and Informatics, Geisinger Health System, Danville, Pa (C.M.H., L.J., B.K.F.); Cardiovascular Research Center, University of Kentucky, Lexington, Ky (C.M.H., L.J., B.K.F.); The Heart Center, St Francis Hospital, Roslyn, NY (J.J.C., J.C.); Cardiovascular Magnetic Resonance Unit, The Royal Brompton Hospital and National Heart and Lung Institute, Imperial College London, London, England (A.D.S., P.F.F.); Department of Radiology & Imaging Sciences and Biomedical Engineering, Emory University, Atlanta, Ga (J.N.O.); Department of Radiology, Stanford University, Stanford, Calif (D.B.E.); Department of Medicine (K.C.B.) and Department of Radiology and Medical Imaging (F.H.E.), University of Virginia Health System, Charlottesville, Va., Ferreira PF; From the Department of Biomedical Engineering, University of Virginia, Biomedical Engineering and Medical Science Building, Room 2013, MR5, Charlottesville, VA 22903 (Y.W., C.S., S.G., D.C.A., F.H.E.); Department of Biomedical, Biological and Chemical Engineering and Department of Radiology, University of Missouri, Columbia, Mo (C.S.); Department of Radiology, University Hospital of Saint Etienne, Saint Etienne, France (P.C.); CREATIS (UMR CNRS 5220, U1206 INSERM), INSA Lyon, Lyon, France (P.C., M.V.); BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, Scotland (K.M., C.B.); Department of Translational Data Science and Informatics, Geisinger Health System, Danville, Pa (C.M.H., L.J., B.K.F.); Cardiovascular Research Center, University of Kentucky, Lexington, Ky (C.M.H., L.J., B.K.F.); The Heart Center, St Francis Hospital, Roslyn, NY (J.J.C., J.C.); Cardiovascular Magnetic Resonance Unit, The Royal Brompton Hospital and National Heart and Lung Institute, Imperial College London, London, England (A.D.S., P.F.F.); Department of Radiology & Imaging Sciences and Biomedical Engineering, Emory University, Atlanta, Ga (J.N.O.); Department of Radiology, Stanford University, Stanford, Calif (D.B.E.); Department of Medicine (K.C.B.) and Department of Radiology and Medical Imaging (F.H.E.), University of Virginia Health System, Charlottesville, Va., Oshinski JN; From the Department of Biomedical Engineering, University of Virginia, Biomedical Engineering and Medical Science Building, Room 2013, MR5, Charlottesville, VA 22903 (Y.W., C.S., S.G., D.C.A., F.H.E.); Department of Biomedical, Biological and Chemical Engineering and Department of Radiology, University of Missouri, Columbia, Mo (C.S.); Department of Radiology, University Hospital of Saint Etienne, Saint Etienne, France (P.C.); CREATIS (UMR CNRS 5220, U1206 INSERM), INSA Lyon, Lyon, France (P.C., M.V.); BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, Scotland (K.M., C.B.); Department of Translational Data Science and Informatics, Geisinger Health System, Danville, Pa (C.M.H., L.J., B.K.F.); Cardiovascular Research Center, University of Kentucky, Lexington, Ky (C.M.H., L.J., B.K.F.); The Heart Center, St Francis Hospital, Roslyn, NY (J.J.C., J.C.); Cardiovascular Magnetic Resonance Unit, The Royal Brompton Hospital and National Heart and Lung Institute, Imperial College London, London, England (A.D.S., P.F.F.); Department of Radiology & Imaging Sciences and Biomedical Engineering, Emory University, Atlanta, Ga (J.N.O.); Department of Radiology, Stanford University, Stanford, Calif (D.B.E.); Department of Medicine (K.C.B.) and Department of Radiology and Medical Imaging (F.H.E.), University of Virginia Health System, Charlottesville, Va., Ennis DB; From the Department of Biomedical Engineering, University of Virginia, Biomedical Engineering and Medical Science Building, Room 2013, MR5, Charlottesville, VA 22903 (Y.W., C.S., S.G., D.C.A., F.H.E.); Department of Biomedical, Biological and Chemical Engineering and Department of Radiology, University of Missouri, Columbia, Mo (C.S.); Department of Radiology, University Hospital of Saint Etienne, Saint Etienne, France (P.C.); CREATIS (UMR CNRS 5220, U1206 INSERM), INSA Lyon, Lyon, France (P.C., M.V.); BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, Scotland (K.M., C.B.); Department of Translational Data Science and Informatics, Geisinger Health System, Danville, Pa (C.M.H., L.J., B.K.F.); Cardiovascular Research Center, University of Kentucky, Lexington, Ky (C.M.H., L.J., B.K.F.); The Heart Center, St Francis Hospital, Roslyn, NY (J.J.C., J.C.); Cardiovascular Magnetic Resonance Unit, The Royal Brompton Hospital and National Heart and Lung Institute, Imperial College London, London, England (A.D.S., P.F.F.); Department of Radiology & Imaging Sciences and Biomedical Engineering, Emory University, Atlanta, Ga (J.N.O.); Department of Radiology, Stanford University, Stanford, Calif (D.B.E.); Department of Medicine (K.C.B.) and Department of Radiology and Medical Imaging (F.H.E.), University of Virginia Health System, Charlottesville, Va., Bilchick KC; From the Department of Biomedical Engineering, University of Virginia, Biomedical Engineering and Medical Science Building, Room 2013, MR5, Charlottesville, VA 22903 (Y.W., C.S., S.G., D.C.A., F.H.E.); Department of Biomedical, Biological and Chemical Engineering and Department of Radiology, University of Missouri, Columbia, Mo (C.S.); Department of Radiology, University Hospital of Saint Etienne, Saint Etienne, France (P.C.); CREATIS (UMR CNRS 5220, U1206 INSERM), INSA Lyon, Lyon, France (P.C., M.V.); BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, Scotland (K.M., C.B.); Department of Translational Data Science and Informatics, Geisinger Health System, Danville, Pa (C.M.H., L.J., B.K.F.); Cardiovascular Research Center, University of Kentucky, Lexington, Ky (C.M.H., L.J., B.K.F.); The Heart Center, St Francis Hospital, Roslyn, NY (J.J.C., J.C.); Cardiovascular Magnetic Resonance Unit, The Royal Brompton Hospital and National Heart and Lung Institute, Imperial College London, London, England (A.D.S., P.F.F.); Department of Radiology & Imaging Sciences and Biomedical Engineering, Emory University, Atlanta, Ga (J.N.O.); Department of Radiology, Stanford University, Stanford, Calif (D.B.E.); Department of Medicine (K.C.B.) and Department of Radiology and Medical Imaging (F.H.E.), University of Virginia Health System, Charlottesville, Va., Epstein FH; From the Department of Biomedical Engineering, University of Virginia, Biomedical Engineering and Medical Science Building, Room 2013, MR5, Charlottesville, VA 22903 (Y.W., C.S., S.G., D.C.A., F.H.E.); Department of Biomedical, Biological and Chemical Engineering and Department of Radiology, University of Missouri, Columbia, Mo (C.S.); Department of Radiology, University Hospital of Saint Etienne, Saint Etienne, France (P.C.); CREATIS (UMR CNRS 5220, U1206 INSERM), INSA Lyon, Lyon, France (P.C., M.V.); BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, Scotland (K.M., C.B.); Department of Translational Data Science and Informatics, Geisinger Health System, Danville, Pa (C.M.H., L.J., B.K.F.); Cardiovascular Research Center, University of Kentucky, Lexington, Ky (C.M.H., L.J., B.K.F.); The Heart Center, St Francis Hospital, Roslyn, NY (J.J.C., J.C.); Cardiovascular Magnetic Resonance Unit, The Royal Brompton Hospital and National Heart and Lung Institute, Imperial College London, London, England (A.D.S., P.F.F.); Department of Radiology & Imaging Sciences and Biomedical Engineering, Emory University, Atlanta, Ga (J.N.O.); Department of Radiology, Stanford University, Stanford, Calif (D.B.E.); Department of Medicine (K.C.B.) and Department of Radiology and Medical Imaging (F.H.E.), University of Virginia Health System, Charlottesville, Va.

Publikováno v: Radiology. Cardiothoracic imaging [Radiol Cardiothorac Imaging] 2023 May 04; Vol. 5 (3), pp. e220196. Date of Electronic Publication: 2023 May 04 (Print Publication: 2023).

Publisher Correction: Endophenotype effect sizes support variant pathogenicity in monogenic disease susceptibility genes.

Autor: Halford JL; Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medicine, Massachusetts General Hospital, Boston, MA, USA., Morrill VN; Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA., Choi SH; Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Jurgens SJ; Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Experimental Cardiology, Amsterdam UMC, Amsterdam, The Netherlands., Melloni G; TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA, USA., Marston NA; TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA, USA., Weng LC; Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA., Nauffal V; Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Hall AW; Gene Regulation Observatory and Epigenomics Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Gunn S; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Austin-Tse CA; Laboratory for Molecular Medicine, Mass General Brigham Personalized Medicine, Cambridge, MA, USA.; Harvard Medical School, Boston, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Pirruccello JP; Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA., Khurshid S; Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.; Demoulas Center for Cardiac Arrhythmias, Massachusetts General Hospital, Boston, MA, USA., Rehm HL; Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard Medical School, Boston, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Benjamin EJ; NHLBI and Boston University's Framingham Heart Study, Framingham, MA, USA.; Department of Medicine, Boston Medical Center, Boston University School of Medicine, Boston, MA, USA.; Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA., Boerwinkle E; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Brody JA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Correa A; Departments of Medicine, Pediatrics and Population Health Science, University of Mississippi Medical Center, Jackson, MS, USA., Fornwalt BK; Department of Translational Data Science and Informatics, Geisinger, Danville, PA, USA.; Heart Institute, Geisinger, Danville, PA, USA.; Department of Radiology, Geisinger, Danville, PA, USA., Gupta N; Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Haggerty CM; Department of Translational Data Science and Informatics, Geisinger, Danville, PA, USA.; Heart Institute, Geisinger, Danville, PA, USA., Harris S; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA., Heckbert SR; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA., Hong CC; University of Maryland School of Medicine, Baltimore, MD, USA., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA., Lin HJ; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Loos RJF; 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Publikováno v: Nature communications [Nat Commun] 2022 Sep 30; Vol. 13 (1), pp. 5767. Date of Electronic Publication: 2022 Sep 30.

Generalizability and quality control of deep learning-based 2D echocardiography segmentation models in a large clinical dataset.

Autor: Zhang X; Department of Translational Data Science and Informatics, Geisinger, 100 North Academy Avenue, Danville, PA, 17822, USA., Cerna AEU; Department of Translational Data Science and Informatics, Geisinger, 100 North Academy Avenue, Danville, PA, 17822, USA., Stough JV; Computer Science, Bucknell University, Lewisburg, PA, USA., Chen Y; Computer Science, Bucknell University, Lewisburg, PA, USA., Carry BJ; Heart Institute, Geisinger, Danville, PA, USA., Alsaid A; Heart Institute, Geisinger, Danville, PA, USA., Raghunath S; Department of Translational Data Science and Informatics, Geisinger, 100 North Academy Avenue, Danville, PA, 17822, USA., vanMaanen DP; Department of Translational Data Science and Informatics, Geisinger, 100 North Academy Avenue, Danville, PA, 17822, USA., Fornwalt BK; Department of Translational Data Science and Informatics, Geisinger, 100 North Academy Avenue, Danville, PA, 17822, USA.; Heart Institute, Geisinger, Danville, PA, USA.; Department of Radiology, Geisinger, Danville, PA, USA., Haggerty CM; Department of Translational Data Science and Informatics, Geisinger, 100 North Academy Avenue, Danville, PA, 17822, USA. chris.m.haggerty@gmail.com.; Heart Institute, Geisinger, Danville, PA, USA. chris.m.haggerty@gmail.com.

Publikováno v: The international journal of cardiovascular imaging [Int J Cardiovasc Imaging] 2022 Aug; Vol. 38 (8), pp. 1685-1697. Date of Electronic Publication: 2022 Feb 24.

rECHOmmend: An ECG-Based Machine Learning Approach for Identifying Patients at Increased Risk of Undiagnosed Structural Heart Disease Detectable by Echocardiography.

Autor: Ulloa-Cerna AE; Department of Translational Data Science and Informatics (A.E.U-C., L.J., J.M.P., S.R., J.A.R., C.W.G., C.M.H., B.K.F., R.C.); Geisinger, Danville, PA., Jing L; Department of Translational Data Science and Informatics (A.E.U-C., L.J., J.M.P., S.R., J.A.R., C.W.G., C.M.H., B.K.F., R.C.); Geisinger, Danville, PA., Pfeifer JM; Department of Translational Data Science and Informatics (A.E.U-C., L.J., J.M.P., S.R., J.A.R., C.W.G., C.M.H., B.K.F., R.C.); Geisinger, Danville, PA.; Heart and Vascular Center, Evangelical Hospital, Lewisburg, PA (J.M.P.).; Tempus Labs Inc, Chicago, IL (J.M.P., S.R., J.B.L., N.Z., G.L., S.R.S., B.K.F., R.C.)., Raghunath S; Department of Translational Data Science and Informatics (A.E.U-C., L.J., J.M.P., S.R., J.A.R., C.W.G., C.M.H., B.K.F., R.C.); Geisinger, Danville, PA.; Tempus Labs Inc, Chicago, IL (J.M.P., S.R., J.B.L., N.Z., G.L., S.R.S., B.K.F., R.C.)., Ruhl JA; Department of Translational Data Science and Informatics (A.E.U-C., L.J., J.M.P., S.R., J.A.R., C.W.G., C.M.H., B.K.F., R.C.); Geisinger, Danville, PA., Rocha DB; Phenomic Analytics and Clinical Data Core (D.B.R., J.B.L.); Geisinger, Danville, PA., Leader JB; Phenomic Analytics and Clinical Data Core (D.B.R., J.B.L.); Geisinger, Danville, PA.; Tempus Labs Inc, Chicago, IL (J.M.P., S.R., J.B.L., N.Z., G.L., S.R.S., B.K.F., R.C.)., Zimmerman N; Tempus Labs Inc, Chicago, IL (J.M.P., S.R., J.B.L., N.Z., G.L., S.R.S., B.K.F., R.C.)., Lee G; Tempus Labs Inc, Chicago, IL (J.M.P., S.R., J.B.L., N.Z., G.L., S.R.S., B.K.F., R.C.)., Steinhubl SR; Tempus Labs Inc, Chicago, IL (J.M.P., S.R., J.B.L., N.Z., G.L., S.R.S., B.K.F., R.C.).; Scripps Research Translational Institute, La Jolla, CA (S.R.S.)., Good CW; Department of Translational Data Science and Informatics (A.E.U-C., L.J., J.M.P., S.R., J.A.R., C.W.G., C.M.H., B.K.F., R.C.); Geisinger, Danville, PA.; Heart and Vascular Institute, University of Pennsylvania Medical Center, Hamot, PA (C.W.G.)., Haggerty CM; Department of Translational Data Science and Informatics (A.E.U-C., L.J., J.M.P., S.R., J.A.R., C.W.G., C.M.H., B.K.F., R.C.); Geisinger, Danville, PA.; Heart Institute (C.M.H., B.K.F.); Geisinger, Danville, PA., Fornwalt BK; Department of Translational Data Science and Informatics (A.E.U-C., L.J., J.M.P., S.R., J.A.R., C.W.G., C.M.H., B.K.F., R.C.); Geisinger, Danville, PA.; Department of Radiology (B.K.F.); Geisinger, Danville, PA.; Heart Institute (C.M.H., B.K.F.); Geisinger, Danville, PA.; Tempus Labs Inc, Chicago, IL (J.M.P., S.R., J.B.L., N.Z., G.L., S.R.S., B.K.F., R.C.)., Chen R; Department of Translational Data Science and Informatics (A.E.U-C., L.J., J.M.P., S.R., J.A.R., C.W.G., C.M.H., B.K.F., R.C.); Geisinger, Danville, PA.; Department of Medicine (R.C.); Geisinger, Danville, PA.; Tempus Labs Inc, Chicago, IL (J.M.P., S.R., J.B.L., N.Z., G.L., S.R.S., B.K.F., R.C.).

Publikováno v: Circulation [Circulation] 2022 Jul 05; Vol. 146 (1), pp. 36-47. Date of Electronic Publication: 2022 May 09.

3D-Encoded DENSE MRI with Zonal Excitation for Quantifying Biventricular Myocardial Strain During a Breath-Hold.

Autor: Carruth ED; Department of Translational Data Science and Informatics, Geisinger, Danville, PA, USA., Fielden SW; Department of Translational Data Science and Informatics, Geisinger, Danville, PA, USA.; Medical and Health Physics, Geisinger, Danville, PA, USA., Nevius CD; Department of Translational Data Science and Informatics, Geisinger, Danville, PA, USA., Fornwalt BK; Department of Translational Data Science and Informatics, Geisinger, Danville, PA, USA.; The Heart Institute, Geisinger, Danville, PA, USA.; Department of Radiology, Geisinger, Danville, PA, USA., Haggerty CM; Department of Translational Data Science and Informatics, Geisinger, Danville, PA, USA. chris.m.haggerty@gmail.com.; The Heart Institute, Geisinger, Danville, PA, USA. chris.m.haggerty@gmail.com.

Publikováno v: Cardiovascular engineering and technology [Cardiovasc Eng Technol] 2021 Dec; Vol. 12 (6), pp. 589-597. Date of Electronic Publication: 2021 Jul 09.