Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Forkhead Transcription Factors - metabolism"'
Autor:
Robert J Harris, Zena Willsmore, Roman Laddach, Silvia Crescioli, Jitesh Chauhan, Anthony Cheung, Anna Black, Jenny L. C. Geh, Alastair D MacKenzie Ross, Ciaran Healy, Sophia Tsoka, James Spicer, Katie E Lacy, Sophia N Karagiannis
Publikováno v:
Harris, R J, Willsmore, Z, Laddach, R, Crescioli, S, Chauhan, J, Cheung, A, Black, A, Geh, J L C, MacKenzie Ross, A D, Healy, C, Tsoka, S, Spicer, J, Lacy, K E & Karagiannis, S N 2022, ' Enriched circulating and tumor-resident TGF-β+ regulatory B cells in patients with melanoma promote FOXP3+ Tregs ', OncoImmunology, vol. 11, no. 1, 2104426, pp. 2104426 . https://doi.org/10.1080/2162402X.2022.2104426
B cells are emerging as key players of anti-tumor adaptive immune responses. We investigated regulatory and pro-inflammatory cytokine-expressing B cells in patients with melanoma by flow cytometric intracellular cytokine, CyTOF, transcriptomic, immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae09673c24a2cdfed4c5599d2860ce6c
https://doi.org/10.1080/2162402x.2022.2104426
https://doi.org/10.1080/2162402x.2022.2104426
Publikováno v:
Nucleic Acids Research
Ji, Z, Li, Y, Liu, S X & Sharrocks, A 2021, ' The forkhead transcription factor FOXK2 premarks lineage-specific genes in human embryonic stem cells for activation during differentiation ', Nucleic acids research, vol. 49, no. 3, gkaa1281, pp. 1345-1363 . https://doi.org/10.1093/nar/gkaa1281
Ji, Z, Li, Y, Liu, S X & Sharrocks, A 2021, ' The forkhead transcription factor FOXK2 premarks lineage-specific genes in human embryonic stem cells for activation during differentiation ', Nucleic acids research, vol. 49, no. 3, gkaa1281, pp. 1345-1363 . https://doi.org/10.1093/nar/gkaa1281
Enhancers play important roles in controlling gene expression in a choreographed spatial and temporal manner during development. However, it is unclear how these regulatory regions are established during differentiation. Here we investigated the geno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6e96e56bc9b30f2609486706e78cc23
http://europepmc.org/articles/PMC7897486
http://europepmc.org/articles/PMC7897486
Autor:
Tatiana V. Petrova, Ying Sun, Maria H. Ulvmar, Alejandra González-Loyola, Ioannis Kritikos, Taija Makinen, Liqun He, Cornelia Halin, Magda Hernandez Vasquez
Publikováno v:
The EMBO journal, vol. 40, no. 12, pp. e107192
The EMBO Journal
The EMBO Journal
The lymphatic system is composed of a hierarchical network of fluid absorbing lymphatic capillaries and transporting collecting vessels. Despite distinct functions and morphologies, molecular mechanisms that regulate the identity of the different ves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04598d1f09ac1984bece55699de81a18
https://serval.unil.ch/resource/serval:BIB_4679CF9489C7.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_4679CF9489C7.P001/REF.pdf
Autor:
Amélie Sabine, Ting Liu, Pieter R. Norden, Ying Wang, Tatiana V. Petrova, Tsutomu Kume, Cansaran Saygili Demir
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife, vol. 9, pp. e53814
eLife
eLife, vol. 9, pp. e53814
Mutations in the transcription factor FOXC2 are predominately associated with lymphedema. Herein, we demonstrate a key role for related factor FOXC1, in addition to FOXC2, in regulating cytoskeletal activity in lymphatic valves. FOXC1 is induced by l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab480b6011954ce8c7cf39a5f40e572c
https://elifesciences.org/articles/53814
https://elifesciences.org/articles/53814
Autor:
Pedro Rodenas-Cuadrado, Tobias A. Schmid, Paolo Devanna, Laura Baas, Michael M. Yartsev, Uwe Firzlaff, Janine Mengede, Sonja C. Vernes
Publikováno v:
Journal of Comparative Neurology
The Journal of Comparative Neurology
The Journal of Comparative Neurology
This work was funded by a Career Integration Grant (Marie Skłodowska‐Curie Actions) (PCIG12‐GA‐2012–333978) and a Max Planck Research Group Grant (Max Planck Gesellschaft) both awarded to S.C.V., and a Human Frontier Science Program (HFSP) R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df2f05d8176c1c7abbe726000fd3c427
https://doi.org/10.1002/cne.24385
https://doi.org/10.1002/cne.24385
Autor:
Sonia Ait-Younes, Mourad Belkhelfa, Chafia Touil-Boukoffa, Yvan de Launoit, Hassen Mahfouf, Hayet Rafa, Nadira Delhem, Hayat Ait-Kaci, Olivier Moralès, Sabah Hetit, Oussama Medjeber, Sarra Benkhelifa, Said Belhadef
Publikováno v:
Inflammopharmacology
Inflammopharmacology, Springer Verlag, 2019, 27 (4), pp.685-700. ⟨10.1007/s10787-019-00566-9⟩
Inflammopharmacology, 2019, 27 (4), pp.685-700. ⟨10.1007/s10787-019-00566-9⟩
Inflammopharmacology, Springer Verlag, 2019, 27 (4), pp.685-700. ⟨10.1007/s10787-019-00566-9⟩
Inflammopharmacology, 2019, 27 (4), pp.685-700. ⟨10.1007/s10787-019-00566-9⟩
International audience; Colorectal cancer (CRC) remains the most cancer type related to chronic inflammation; however, the mechanisms that link inflammation to CRC development and progression are still poorly understood. Our study aimed to investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90c14e2c54400f0d81e84b20996df275
https://hal.archives-ouvertes.fr/hal-03059991
https://hal.archives-ouvertes.fr/hal-03059991
Autor:
Jean-Pierre Mach, Guerric Samson, Marten Meyer, Pedro Romero, Lianjun Zhang, Michael N. Hall, Isabel C. Lopez-Mejia, Markus A. Rüegg, Benjamin O. Tschumi, Susanne Oberle, Dietmar Zehn, Lluis Fajas, Alena Donda
Publikováno v:
Cell Reports, vol. 14, no. 5, pp. 1206-1217
Cell reports
Cell Reports, Vol 14, Iss 5, Pp 1206-1217 (2016)
Cell reports
Cell Reports, Vol 14, Iss 5, Pp 1206-1217 (2016)
Summary: Upon infection, antigen-specific naive CD8 T cells are activated and differentiate into short-lived effector cells (SLECs) and memory precursor cells (MPECs). The underlying signaling pathways remain largely unresolved. We show that Rictor,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4acf82e3c3d40f750dac5b5bdbac915c
https://doi.org/10.1016/j.celrep.2015.12.095
https://doi.org/10.1016/j.celrep.2015.12.095
Autor:
Janice W. H. Tsang, Aleksandra K. Zwolinska, Anne Feltes, San Yu Wong, Ui-Soon Khoo, Maja Petkovic, Ana R. Gomes, Yuen-Nei Cheung, Christina T. Karadedou, Jie Chen, Eric Lam, Ka-Kei Ho, Jan J. Brosens, Kelvin Y.K. Chan
Publikováno v:
Oncogene
Vascular endothelial growth factor (VEGF) has a central role in breast cancer development and progression, but the mechanisms that control its expression are poorly understood. Breast cancer tissue microarrays revealed an inverse correlation between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::335e693c6476e0b592ffc7472296807a
https://doi.org/10.1038/onc.2011.368
https://doi.org/10.1038/onc.2011.368
Autor:
Lukas Flatz, Pascale Zwicky, Alexander A. Navarini, Phil F. Cheng, Burkhard Becher, Reinhard Dummer, Tom Hartwig, Nikhil Yawalkar, Curdin Conrad, Bettina Schreiner, Christoph Schlapbach
Publikováno v:
Cell Reports, Vol 25, Iss 13, Pp 3564-3572.e4 (2018)
Cell reports, vol. 25, no. 13, pp. 3564-3572.e4
Hartwig, Tom; Zwicky, Pascale; Schreiner, Bettina; Yawalkar, Nikhil; Cheng, Phil; Navarini, Alexander; Dummer, Reinhard; Flatz, Lukas; Conrad, Curdin; Schlapbach, Christoph; Becher, Burkhard (2018). Regulatory T Cells Restrain Pathogenic T Helper Cells during Skin Inflammation. Cell reports, 25(13), 3564-3572.e4. Cell Press 10.1016/j.celrep.2018.12.012
Cell reports, vol. 25, no. 13, pp. 3564-3572.e4
Hartwig, Tom; Zwicky, Pascale; Schreiner, Bettina; Yawalkar, Nikhil; Cheng, Phil; Navarini, Alexander; Dummer, Reinhard; Flatz, Lukas; Conrad, Curdin; Schlapbach, Christoph; Becher, Burkhard (2018). Regulatory T Cells Restrain Pathogenic T Helper Cells during Skin Inflammation. Cell reports, 25(13), 3564-3572.e4. Cell Press 10.1016/j.celrep.2018.12.012
Summary: Psoriasis is a chronic relapsing, remitting interleukin (IL)-23/IL-17-driven skin disease mediated by the interplay of T cells and polymorphonuclear granulocytes. Although preclinical studies have provided insights into the mechanisms of dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f131119d7f83da2ba133932aa15121a7
https://doi.org/10.1016/j.celrep.2018.12.012
https://doi.org/10.1016/j.celrep.2018.12.012
Autor:
Johanna Liebl, Markus Moser, Friedemann Kiefer, Tatiana V. Petrova, Bianca Hager, Yan Agalarov, Ralf H. Adams, Cansaran Saygili Demir, Stefan Zahler, Naoyuki Miura, Angelika M. Vollmar, Siwei Zhang, James A. Bibb
Publikováno v:
Nature Communications, vol. 6, pp. 7274
Nature communications
Nature communications
The lymphatic system maintains tissue fluid balance, and dysfunction of lymphatic vessels and valves causes human lymphedema syndromes. Yet, our knowledge of the molecular mechanisms underlying lymphatic vessel development is still limited. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f64e6258bd942bb6487ae36f8196958
https://serval.unil.ch/resource/serval:BIB_3B60F81231F4.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_3B60F81231F4.P001/REF.pdf