Plant resistance and predators influence the density dependence of herbivore survival and distribution of herbivory.

Autor: Paniagua Montoya M; Department of Biological Science Florida State University Tallahassee Florida USA., Forde AJ; Department of Entomology University of Maryland College Park Maryland USA., Inouye B; Department of Biological Science Florida State University Tallahassee Florida USA., Underwood N; Department of Biological Science Florida State University Tallahassee Florida USA.

Publikováno v: Ecology and evolution [Ecol Evol] 2024 Aug 07; Vol. 14 (8), pp. e70106. Date of Electronic Publication: 2024 Aug 07 (Print Publication: 2024).

Metabolic rewiring tunes dermal macrophages in staphylococcal skin infection.

Autor: Forde AJ; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center and Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.; Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany., Kolter J; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center and Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany., Zwicky P; Institute of Experimental Immunology, University of Zurich, CH-8057 Zurich, Switzerland., Baasch S; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center and Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany., Lohrmann F; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center and Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.; Spemann Graduate School of Biology and Medicine, University of Freiburg, 79104 Freiburg, Germany.; Center for Pediatrics and Adolescent Medicine, University Medical Center, 79106 Freiburg, Germany., Eckert M; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center and Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.; Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany., Gres V; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center and Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.; Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany., Lagies S; Spemann Graduate School of Biology and Medicine, University of Freiburg, 79104 Freiburg, Germany.; 1 Core Competence Metabolomics, Institute of Organic Chemistry, University of Freiburg, 79104 Freiburg, Germany., Gorka O; Institute of Neuropathology, Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany., Rambold AS; Department of Developmental Immunology, Max-Planck-Institute of Immunobiology and Epigenetics, Freiburg, Germany., Buescher JM; Department of Immunometabolism, Max-Planck-Institute of Immunobiology and Epigenetics, Freiburg, Germany., Kammerer B; Spemann Graduate School of Biology and Medicine, University of Freiburg, 79104 Freiburg, Germany.; 1 Core Competence Metabolomics, Institute of Organic Chemistry, University of Freiburg, 79104 Freiburg, Germany.; Signalling Research Centre's BIOSS and CIBSS, University of Freiburg, 79104 Freiburg, Germany., Lachmann N; Department of Pediatric Pneumology, Allergology and Neonatology and Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, 30625 Hannover, Germany., Prinz M; Institute of Neuropathology, Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Signalling Research Centre's BIOSS and CIBSS, University of Freiburg, 79104 Freiburg, Germany.; Center for Basics in NeuroModulation (NeuroModulBasics), Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.; CIBSS-Center for Integrative Biological Signaling Studies, University of Freiburg, 79104 Freiburg, Germany., Groß O; Institute of Neuropathology, Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Signalling Research Centre's BIOSS and CIBSS, University of Freiburg, 79104 Freiburg, Germany.; Center for Basics in NeuroModulation (NeuroModulBasics), Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.; CIBSS-Center for Integrative Biological Signaling Studies, University of Freiburg, 79104 Freiburg, Germany., Pearce EJ; Department of Immunometabolism, Max-Planck-Institute of Immunobiology and Epigenetics, Freiburg, Germany., Becher B; Institute of Experimental Immunology, University of Zurich, CH-8057 Zurich, Switzerland., Henneke P; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center and Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.; Center for Pediatrics and Adolescent Medicine, University Medical Center, 79106 Freiburg, Germany.; CIBSS-Center for Integrative Biological Signaling Studies, University of Freiburg, 79104 Freiburg, Germany.

Publikováno v: Science immunology [Sci Immunol] 2023 Aug 18; Vol. 8 (86), pp. eadg3517. Date of Electronic Publication: 2023 Aug 11.

Intracellular infection and immune system cues rewire adipocytes to acquire immune function.

Autor: Caputa G; Department of Immunometabolism, Max Planck Institute for Immunobiology and Epigenetics, 79108 Freiburg, Germany., Matsushita M; Department of Immunometabolism, Max Planck Institute for Immunobiology and Epigenetics, 79108 Freiburg, Germany., Sanin DE; Department of Immunometabolism, Max Planck Institute for Immunobiology and Epigenetics, 79108 Freiburg, Germany; Bloomberg Kimmel Institute, and Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Kabat AM; Department of Immunometabolism, Max Planck Institute for Immunobiology and Epigenetics, 79108 Freiburg, Germany., Edwards-Hicks J; Department of Immunometabolism, Max Planck Institute for Immunobiology and Epigenetics, 79108 Freiburg, Germany., Grzes KM; Department of Immunometabolism, Max Planck Institute for Immunobiology and Epigenetics, 79108 Freiburg, Germany., Pohlmeyer R; Imaging Facility, Max Planck Institute for Immunobiology and Epigenetics, 79108 Freiburg, Germany., Stanczak MA; Department of Immunometabolism, Max Planck Institute for Immunobiology and Epigenetics, 79108 Freiburg, Germany., Castoldi A; Department of Immunometabolism, Max Planck Institute for Immunobiology and Epigenetics, 79108 Freiburg, Germany., Cupovic J; Department of Immunometabolism, Max Planck Institute for Immunobiology and Epigenetics, 79108 Freiburg, Germany., Forde AJ; Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany; Center for Chronic Immune Deficiency, Faculty of Medicine, University of Freiburg, 79104 Freiburg, Germany., Apostolova P; Department of Immunometabolism, Max Planck Institute for Immunobiology and Epigenetics, 79108 Freiburg, Germany., Seidl M; Center for Chronic Immune Deficiency, Faculty of Medicine, University of Freiburg, 79104 Freiburg, Germany; Institute of Surgical Pathology, Faculty of Medicine, Medical Center, University of Freiburg, 79104 Freiburg, Germany; Institute of Pathology, Heinrich Heine University and University Hospital of Duesseldorf, 40225 Duesseldorf, Germany., van Teijlingen Bakker N; Department of Immunometabolism, Max Planck Institute for Immunobiology and Epigenetics, 79108 Freiburg, Germany; Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany., Villa M; Department of Immunometabolism, Max Planck Institute for Immunobiology and Epigenetics, 79108 Freiburg, Germany., Baixauli F; Department of Immunometabolism, Max Planck Institute for Immunobiology and Epigenetics, 79108 Freiburg, Germany., Quintana A; Department of Immunometabolism, Max Planck Institute for Immunobiology and Epigenetics, 79108 Freiburg, Germany., Hackl A; Department of Immunometabolism, Max Planck Institute for Immunobiology and Epigenetics, 79108 Freiburg, Germany., Flachsmann L; Department of Immunometabolism, Max Planck Institute for Immunobiology and Epigenetics, 79108 Freiburg, Germany., Hässler F; Department of Immunometabolism, Max Planck Institute for Immunobiology and Epigenetics, 79108 Freiburg, Germany., Curtis JD; Department of Immunometabolism, Max Planck Institute for Immunobiology and Epigenetics, 79108 Freiburg, Germany., Patterson AE; Department of Immunometabolism, Max Planck Institute for Immunobiology and Epigenetics, 79108 Freiburg, Germany., Henneke P; Center for Chronic Immune Deficiency, Faculty of Medicine, University of Freiburg, 79104 Freiburg, Germany., Pearce EL; Department of Immunometabolism, Max Planck Institute for Immunobiology and Epigenetics, 79108 Freiburg, Germany; Bloomberg Kimmel Institute, and Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA; Department of Biochemistry and Molecular Biology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21287, USA. Electronic address: epearce6@jhmi.edu., Pearce EJ; Department of Immunometabolism, Max Planck Institute for Immunobiology and Epigenetics, 79108 Freiburg, Germany; Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany; Bloomberg Kimmel Institute, and Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA; Department of Molecular Microbiology and Immunology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21287, USA. Electronic address: epearce7@jhmi.edu.

Publikováno v: Cell metabolism [Cell Metab] 2022 May 03; Vol. 34 (5), pp. 747-760.e6.

Monocyte progenitors give rise to multinucleated giant cells.

Autor: Lösslein AK; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany.; MOTI-VATE Graduate School, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Lohrmann F; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Center for Pediatrics and Adolescent Medicine, Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Spemann Graduate School for Biology and Medicine (SGBM) and IMM-PACT Clinician Scientist Program, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Scheuermann L; Max Planck Institute for Infection Biology, Berlin, Germany., Gharun K; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany., Neuber J; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany., Kolter J; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany., Forde AJ; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany., Kleimeyer C; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany., Poh YY; Nanyang Technological University, Lee Kong Chian School of Medicine, Singapore, Singapore., Mack M; University Hospital Regensburg, Internal Medicine II, Nephrology, Regensburg, Germany., Triantafyllopoulou A; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany.; German Rheumatism Research Centre Berlin, Leibniz Association, Berlin, Germany., Dunlap MD; Department of Molecular Microbiology, Washington University in St. Louis School of Medicine, Saint Louis, MO, USA.; Department of Pathology and Immunology, Washington University in St. Louis School of Medicine, Saint Louis, MO, USA., Khader SA; Department of Molecular Microbiology, Washington University in St. Louis School of Medicine, Saint Louis, MO, USA.; Department of Pathology and Immunology, Washington University in St. Louis School of Medicine, Saint Louis, MO, USA., Seidl M; Center for Chronic Immunodeficiency and Institute for Clinical Pathology, Department of Pathology, Medical Center and Faculty of Medicine, Freiburg, Germany and Institute of Pathology, Heinrich Heine University and University Hospital of Duesseldorf, Duesseldorf, Germany., Hölscher A; Forschungszentrum Borstel, Leibniz Lungenzentrum, Borstel, Germany., Hölscher C; Forschungszentrum Borstel, Leibniz Lungenzentrum, Borstel, Germany.; Deutsches Zentrum für Infektionsforschung, Standort Borstel, Borstel, Germany., Guan XL; Nanyang Technological University, Lee Kong Chian School of Medicine, Singapore, Singapore., Dorhoi A; Max Planck Institute for Infection Biology, Berlin, Germany.; Institute of Immunology, Federal Research Institute for Animal Health, Friedrich-Loeffler-Institut (FLI), Insel Riems, Germany.; Faculty of Mathematics and Natural Sciences, University of Greifswald, Greifswald, Germany., Henneke P; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany. Philipp.henneke@uniklinik-freiburg.de.; Center for Pediatrics and Adolescent Medicine, Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany. Philipp.henneke@uniklinik-freiburg.de.

Publikováno v: Nature communications [Nat Commun] 2021 Apr 01; Vol. 12 (1), pp. 2027. Date of Electronic Publication: 2021 Apr 01.

Resident macrophages acquire innate immune memory in staphylococcal skin infection.

Autor: Feuerstein R; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Forde AJ; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany., Lohrmann F; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Center for Pediatrics and Adolescent Medicine, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Spemann Graduate School of Biology and Medicine (SGBM), Faculty of Biology, University of Freiburg and IMM-PACT Clinician Scientist Program, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Kolter J; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Ramirez NJ; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Zimmermann J; Maurice Müller Laboratories (Department for Biomedical Research), Universitätsklinik für Viszerale Chirurgie und Medizin Inselspital, University of Bern, Bern, Switzerland., Gomez de Agüero M; Maurice Müller Laboratories (Department for Biomedical Research), Universitätsklinik für Viszerale Chirurgie und Medizin Inselspital, University of Bern, Bern, Switzerland., Henneke P; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Center for Pediatrics and Adolescent Medicine, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Publikováno v: ELife [Elife] 2020 Jul 08; Vol. 9. Date of Electronic Publication: 2020 Jul 08.