Prospective multiparametric CMR characterization and MicroRNA profiling of anthracycline cardiotoxicity: A pilot translational study

Autor: Harries, Iwan, Biglino, Giovanni, Ford, Kerrie, Nelson, Martin, Rego, Gui, Srivastava, Prashant, Williams, Matthew, Berlot, Bostjan, De Garate, Estefania, Baritussio, Anna, Liang, Kate, Baquedano, Mai, Chavda, Nikesh, Lawton, Christopher, Shearn, Andrew, Otton, Sophie, Lowry, Lisa, Nightingale, Angus K., Carlos Plana, Juan, Marks, David, Emanueli, Costanza, Bucciarelli-Ducci, Chiara

Publikováno v: In IJC Heart & Vasculature December 2022 43

Elevated cyclic-AMP represses expression of exchange protein activated by cAMP (EPAC1) by inhibiting YAP-TEAD activity and HDAC-mediated histone deacetylation

Autor: Ebrahimighaei, Reza, McNeill, Madeleine C., Smith, Sarah A., Wray, Jason P., Ford, Kerrie L., Newby, Andrew C., Bond, Mark

Publikováno v: In BBA - Molecular Cell Research October 2019 1866(10):1634-1649

Optimisation of laboratory methods for whole transcriptomic RNA analyses in human left ventricular biopsies and blood samples of clinical relevance.

Autor: Ford, Kerrie L.^1,2, Anwar, Maryam¹, Heys, Rachael³, Ahmed, Eltayeb Mohamed², Caputo, Massimo^2,4, Game, Laurence⁵, Reeves, Barnaby C.³, Punjabi, Prakash P.^1,6, Angelini, Gianni D.^2,4, Petretto, Enrico^5,7, Emanueli, Costanza^1,2 c.emanueli@imperial.ac.uk

Publikováno v: PLoS ONE. 3/14/2019, Vol. 14 Issue 3, p1-18. 18p.

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MicroRNA-24 targets Notch and other vascular morphogens to regulates post-ischemic microvascular responses in limb muscles

Autor: Marchetti, Micol, Meloni, Marco, Anwar, Maryam, Al Haj Zen, Ayman, Sala-Newby, Graciela, Slater, Sadie C, Ford, Kerrie, Caporali, Andrea, Emanueli, Costanza

Publikováno v: Marchetti, M, Meloni, M, Anwar, M, Al Haj Zen, A, Sala-Newby, G, Slater, S C, Ford, K, Caporali, A & Emanueli, C 2020, ' MicroRNA-24 targets Notch and other vascular morphogens to regulates post-ischemic microvascular responses in limb muscles ', International Journal of Molecular Sciences, vol. 21, no. 5, 1733 . https://doi.org/10.3390/ijms21051733

MicroRNAs (miRs) regulate complex processes, including angiogenesis, by targeting multiple mRNAs. miR-24-3p-3p directly represses eNOS, GATA2, and PAK4 in endothelial cells (ECs), thus inhibiting angiogenesis during development and in the infarcted h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2642::6913166f2282188c113322432b2260d4
https://research-information.bris.ac.uk/en/publications/c0948cf7-0eed-4fe1-a9db-293b07f72cc6