Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Fontolizumab"'
Autor:
M. Cheng, S. J. H. Van Deventer, G. Van Assche, Lixiao Zhang, Walter Reinisch, Bas Oldenburg, Jean-Frederic Colombel, Meina Tang, K. Geboes, Daan W. Hommes, H. Ding, Alexander Teml, Jean-Pierre Gendre, Paul Rutgeerts, T. Pearce
Publikováno v:
Gut, 55(8), 1138-1144. BMJ Publishing Group
This study was designed to evaluate the safety of fontolizumab, a humanised anti-interferon gamma antibody, in patients with moderate to severe Crohn's disease (CD). Forty five patients with a CD activity index (CDAI) of 250-450 were randomised in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d54101a418348fc3cb3eb2368994b365
https://doi.org/10.1136/gut.2005.079434
https://doi.org/10.1136/gut.2005.079434
Autor:
Arthur Kaser
Publikováno v:
Best practiceresearch. Clinical gastroenterology. 28(3)
The recent success of the anti-integrin antibody Vedolizumab can barely conceal the fact that the biologics armamentarium in Crohn's disease has barely evolved beyond TNF blockers so far. This contrasts with other immune-related diseases considered m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2439b64bf4be23af78cd1593266ab38d
https://pubmed.ncbi.nlm.nih.gov/24913383
https://pubmed.ncbi.nlm.nih.gov/24913383
Akademický článek
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Publikováno v:
Gut. 55:1071-1073
Interferon gamma is a potent proinflammatory cytokine implicated in the inflammation of Crohn's disease (CD). We evaluated the safety and efficacy of fontolizumab, a humanised anti-interferon gamma antibody, in patients with moderate to severe CD.A t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::350ec7fa3e7ebaeb509b12c5eabd9ea7
https://doi.org/10.1136/gut.2005.090134
https://doi.org/10.1136/gut.2005.090134
Autor:
László Simon, Brian G. Feagan, Michael Marion Gaspari, T. Pearce, Daniel W. Hommes, Walter Reinisch, István Rácz, László Bene, Dennis Riff, István Altorjay, Williem de Villiers, Bruce E. Sands, Paul Rutgeerts, Seymour Katz, May Cheng, Antoine Cortot, Charles N. Bernstein
Background: The safety and efficacy of fontolizumab, a humanized anti-interferon gamma antibody, was investigated in patients with Crohn's disease (CD). Elevated gut mucosal levels of interferon gamma, a key cytokine involved in the inflammatory proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6073d1e0464ddae1a09f6de030757ce
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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K zobrazení výsledku je třeba se přihlásit.
Autor:
S. Stoinov, S Lee, T. Pearce, Mária Zakuciová, János Lonovics, G. Van Assche, S. Ba, Boris Vucelić, G. D'Haens, T. L. Mikhajlova, Davor Štimac, Daan W. Hommes
Publikováno v:
Gut, 55(8), 1131-1137. BMJ Publishing Group
INTRODUCTION: Interferon gamma is a potent proinflammatory cytokine implicated in the inflammation of Crohn's disease (CD). We evaluated the safety and efficacy of fontolizumab, a humanised anti-interferon gamma antibody, in patients with moderate to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af21b0c05b23992282904d1ccbb110d4
https://pure.amc.nl/en/publications/fontolizumab-a-humanised-antiinterferon-gamma-antibody-demonstrates-safety-and-clinical-activity-in-patients-with-moderate-to-severe-crohns-disease(56c8e667-8a5b-4b5e-9940-b6e6ee78c198).html
https://pure.amc.nl/en/publications/fontolizumab-a-humanised-antiinterferon-gamma-antibody-demonstrates-safety-and-clinical-activity-in-patients-with-moderate-to-severe-crohns-disease(56c8e667-8a5b-4b5e-9940-b6e6ee78c198).html
Autor:
G.R. Lichtenstein
Publikováno v:
Yearbook of Gastroenterology. 2007:122-123
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec646e840240d5cbd805d47e25961932
https://doi.org/10.1016/s0739-5930(08)70102-8
https://doi.org/10.1016/s0739-5930(08)70102-8
Autor:
David Bernardo Ordiz, Hafid O. Al-Hassi, Aravinth U. Murugananthan, Phil Tozer, Naila Arebi, Elizabeth R. Mann, Stella C. Knight, Cheng T. Tee, Ailsa Hart
Publikováno v:
Gastroenterology. 140:S-840
Introduction Th1 and Th17 pathways are implicated in Crohn9s disease (CD). In operative resection samples healthy ileum shows high TGFβ levels in patients who develop recurrence, with TGFβ being a known activator of the Th17 response. Other studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3889b6f70bc4bf75ad57947685e9522
https://doi.org/10.1016/s0016-5085(11)63483-5
https://doi.org/10.1016/s0016-5085(11)63483-5
Autor:
T. Pearce, Mária Zakuciová, Gert Van Assche, S. Stoinov, János Lonovics, Davor Štimac, Geert R. D'Haens, Daniel W. Hommes, Boris Vucelić, Tatiana Mikhajlova
Publikováno v:
Gastroenterology. 127:332
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7d8c01f9e5ae3097680eeb5702e4baf
https://doi.org/10.1053/j.gastro.2004.05.011
https://doi.org/10.1053/j.gastro.2004.05.011