Anti-hyperalgesic effect of (-)-α-bisabolol and (-)-α-bisabolol/β-Cyclodextrin complex in a chronic inflammatory pain model is associated with reduced reactive gliosis and cytokine modulation.

Autor: Fontinele LL; Multiuser Health Center Facility (CMulti-Saúde), Brazil., Heimfarth L; Multiuser Health Center Facility (CMulti-Saúde), Brazil., Pereira EWM; Multiuser Health Center Facility (CMulti-Saúde), Brazil., Rezende MM; Multiuser Health Center Facility (CMulti-Saúde), Brazil., Lima NT; Multiuser Health Center Facility (CMulti-Saúde), Brazil., Barbosa Gomes de Carvalho YM; Department of Pharmacy. Federal University of Sergipe, São Cristóvão, SE, 49100-000, Brazil., Afonso de Moura Pires E; Faculdade de Enfermagem Nova Esperança (FACENE), Brazil., Guimarães AG; Multiuser Health Center Facility (CMulti-Saúde), Brazil., Bezerra Carvalho MT; Multiuser Health Center Facility (CMulti-Saúde), Brazil., de Souza Siqueira Barreto R; Multiuser Health Center Facility (CMulti-Saúde), Brazil., Campos AR; Experimental Biology Center, University of Fortaleza, Fortaleza, Ceará, Brazil., Antoniolli AR; Multiuser Health Center Facility (CMulti-Saúde), Brazil., Antunes de Souza Araújo A; Department of Pharmacy. Federal University of Sergipe, São Cristóvão, SE, 49100-000, Brazil., Quintans-Júnior LJ; Multiuser Health Center Facility (CMulti-Saúde), Brazil., de Souza Siqueira Quintans J; Multiuser Health Center Facility (CMulti-Saúde), Brazil. Electronic address: jullyanaquintans@gmail.com.

Publikováno v: Neurochemistry international [Neurochem Int] 2019 Dec; Vol. 131, pp. 104530. Date of Electronic Publication: 2019 Aug 16.