Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Fontaine Widmayer"'
Autor:
Kerstin Wolk, Maximilian Schielein, Julia-Tatjana Maul, Fontaine Widmayer, Kerstin Wanke, Wolfgang Fischmann, Petra Nathan, Robert Sabat
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
BackgroundChronic inflammatory skin diseases (CISDs) are among the most common diseases in the Western world. Current estimates of medical care for CISDs are primarily based on surveys among patients in medical care facilities and on health insurance
Externí odkaz:
https://doaj.org/article/045b4a5dfbaf4f2596877a763c6621c0
Autor:
Dario Neri, Sarah Wulhfard, Francesca Pretto, Giovanni Pellegrini, Patrizia Murer, Fontaine Widmayer, Barbara Ziffels, Samuele Cazzamalli
Purpose: Antibody–drug conjugates and small-molecule-drug conjugates have been proposed as alternatives to conventional anticancer cytotoxic agents, with the potential to deliver bioactive payloads to the site of disease, helping spare normal tissu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14149ef935aed0fd12e066349bb00090
https://doi.org/10.1158/1078-0432.c.6527540.v1
https://doi.org/10.1158/1078-0432.c.6527540.v1
Autor:
Dario Neri, Sarah Wulhfard, Francesca Pretto, Giovanni Pellegrini, Patrizia Murer, Fontaine Widmayer, Barbara Ziffels, Samuele Cazzamalli
Detailed synthetic procedures, chemical and biological characterization of relevant compounds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7192318ac311ff8cfca3bfade48295ab
https://doi.org/10.1158/1078-0432.22470368
https://doi.org/10.1158/1078-0432.22470368
Publikováno v:
Cancer Research. 78:758-758
In an attempt to improve the therapeutic index of cancer chemotherapy, monoclonal antibodies and small organic ligands have been proposed as delivery vehicles, allowing the construction of antibody-drug conjugates (ADCs) and of small molecule-drug co
Autor:
Patrizia Murer, Sarah Wulhfard, Francesca Pretto, Giovanni Pellegrini, Samuele Cazzamalli, Barbara Ziffels, Dario Neri, Fontaine Widmayer
Publikováno v:
Clinical Cancer Research, 24 (15)
Clinical Cancer Research
Clinical Cancer Research
Purpose: Antibody–drug conjugates and small-molecule-drug conjugates have been proposed as alternatives to conventional anticancer cytotoxic agents, with the potential to deliver bioactive payloads to the site of disease, helping spare normal tissu
Publikováno v:
Journal of the American Chemical Society
Journal of the American Chemical Society, 140 (5)
Journal of the American Chemical Society, 140 (5)
We present the first direct comparative evaluation of an antibody–drug conjugate and of a small molecule–drug conjugate for cancer therapy, using chemically defined products which bind with high-affinity to carbonic anhydrase IX, a marker of tumo