Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Fonseca KR"'
Autor:
Garnsey MR; Pfizer, Incorporated, Cambridge, Massachusetts 02139, United States., Smith AC; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Polivkova J; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Arons AL; Pfizer, Incorporated, Cambridge, Massachusetts 02139, United States., Bai G; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Blakemore C; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Boehm M; Pfizer, Incorporated, Cambridge, Massachusetts 02139, United States., Buzon LM; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Campion SN; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Cerny M; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Chang SC; Pfizer, Incorporated, Cambridge, Massachusetts 02139, United States., Coffman K; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Farley KA; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Fonseca KR; Pfizer, Incorporated, Cambridge, Massachusetts 02139, United States., Ford KK; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Garren J; Pfizer, Incorporated, Cambridge, Massachusetts 02139, United States., Kong JX; Pfizer, Incorporated, Cambridge, Massachusetts 02139, United States., Koos MRM; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Kung DW; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Lian Y; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Li MM; Pfizer, Incorporated, Cambridge, Massachusetts 02139, United States., Li Q; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Martinez-Alsina LA; Pfizer, Incorporated, Groton, Connecticut 06340, United States., O'Connor R; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Ogilvie K; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Omoto K; Pfizer, Incorporated, Cambridge, Massachusetts 02139, United States., Raymer B; Pfizer, Incorporated, Cambridge, Massachusetts 02139, United States., Reese MR; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Ryder T; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Samp L; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Stevens KA; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Widlicka DW; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Yang Q; Pfizer, Incorporated, Cambridge, Massachusetts 02139, United States., Zhu K; Pfizer, Incorporated, Groton, Connecticut 06340, United States., Fortin JP; Pfizer, Incorporated, Cambridge, Massachusetts 02139, United States., Sammons MF; Pfizer, Incorporated, Cambridge, Massachusetts 02139, United States.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2023 Mar 09; Vol. 66 (5), pp. 3195-3211. Date of Electronic Publication: 2023 Feb 19.
Autor:
Tess DA; Pharmacokinetics, Dynamics and Metabolism, Medicine Design, Worldwide Research & Development, Pfizer Inc, Cambridge, Massachusetts, USA., Kimoto E; Pharmacokinetics, Dynamics and Metabolism, Medicine Design, Worldwide Research & Development, Pfizer Inc., Groton, Connecticut, USA., King-Ahmad A; Pharmacokinetics, Dynamics and Metabolism, Medicine Design, Worldwide Research & Development, Pfizer Inc., Groton, Connecticut, USA., Vourvahis M; Clinical Pharmacology, Global Product Development, Pfizer Inc, New York, New York, USA., Rodrigues AD; Pharmacokinetics, Dynamics and Metabolism, Medicine Design, Worldwide Research & Development, Pfizer Inc., Groton, Connecticut, USA., Bergman A; Clinical Pharmacology, Early Clinical Development, Pfizer Inc., Cambridge, Massachusetts, USA., Qui R; Clinical Pharmacology, Early Clinical Development, Pfizer Inc., Cambridge, Massachusetts, USA., Somayaji V; Clinical Biostatistics, Early Clinical Development, Pfizer Inc, Cambridge, Massachusetts, USA., Weng Y; Clinical Pharmacology, Early Clinical Development, Pfizer Inc., Cambridge, Massachusetts, USA., Fonseca KR; Pharmacokinetics, Dynamics and Metabolism, Medicine Design, Worldwide Research & Development, Pfizer Inc, Cambridge, Massachusetts, USA., Litchfield J; Pharmacokinetics, Dynamics and Metabolism, Medicine Design, Worldwide Research & Development, Pfizer Inc, Cambridge, Massachusetts, USA., Varma MVS; Pharmacokinetics, Dynamics and Metabolism, Medicine Design, Worldwide Research & Development, Pfizer Inc., Groton, Connecticut, USA.
Publikováno v:
Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2022 Sep; Vol. 112 (3), pp. 605-614. Date of Electronic Publication: 2022 May 09.
Autor:
Weng Y; Pharmacokinetics, Dynamics and Metabolism, Pfizer Inc., United States., Fonseca KR; PDM, Pfizer Inc, United States., Bi YA; Pfizer Inc., United States., Mathialagan S; Pharmacokinetics, Pharmacodynamics, and Metabolism, Medicine Design, Pfizer Inc, United States., Riccardi K; Pfizer, United States., Tseng E; Pharmacokinetics, Dynamics, and Metabolism, Pfizer Global Research and Development, United States., Bessire AJ; Pfizer, United States., Cerny MA; PDM, Pfizer Global Research and Development, United States., Tess DA; Medicine Design, Pfizer Inc., United States., Rodrigues AD; Drug Metabolism and Pharmacokinetics, Pfizer, United States., Kalgutkar AS; Medicine Design, Pfizer Worldwide Research and Development, United States., Litchfield JE; PDM, Pfizer, United States., Di L; Pharmacokintics Dynamics and Metabolism, Pfizer Inc., United States., Varma MVS; Pharmacokinetics Dynamics and Metabolism, Pfizer Inc, United States manthena.v.varma@pfizer.com.
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2022 Jul 02. Date of Electronic Publication: 2022 Jul 02.
Autor:
Arakawa R; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Karolinska University Hospital Solna, R5:02, 17176, Stockholm, Sweden. ryosuke.arakawa@ki.se.; Stockholm Health Care Services, Stockholm County Council, Stockholm, Sweden. ryosuke.arakawa@ki.se., Takano A; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Karolinska University Hospital Solna, R5:02, 17176, Stockholm, Sweden.; Stockholm Health Care Services, Stockholm County Council, Stockholm, Sweden., Nag S; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Karolinska University Hospital Solna, R5:02, 17176, Stockholm, Sweden.; Stockholm Health Care Services, Stockholm County Council, Stockholm, Sweden., Jia Z; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Karolinska University Hospital Solna, R5:02, 17176, Stockholm, Sweden.; Stockholm Health Care Services, Stockholm County Council, Stockholm, Sweden., Amini N; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Karolinska University Hospital Solna, R5:02, 17176, Stockholm, Sweden.; Stockholm Health Care Services, Stockholm County Council, Stockholm, Sweden., Maresca KP; Worldwide Research and Development, Pfizer Inc., Cambridge, MA, USA., Zhang L; Worldwide Research and Development, Pfizer Inc., Cambridge, MA, USA., Keliher EJ; Worldwide Research and Development, Pfizer Inc., Cambridge, MA, USA., Butler CR; Worldwide Research and Development, Pfizer Inc., Cambridge, MA, USA., Piro JR; Worldwide Research and Development, Pfizer Inc., Cambridge, MA, USA., Samad TA; Worldwide Research and Development, Pfizer Inc., Cambridge, MA, USA., Smith D; Worldwide Research and Development, Pfizer Inc., Cambridge, MA, USA., Nason D; Worldwide Research and Development, Pfizer Inc., Cambridge, MA, USA., O'Neil S; Worldwide Research and Development, Pfizer Inc., Cambridge, MA, USA., Trapa P; Worldwide Research and Development, Pfizer Inc., Cambridge, MA, USA., Fonseca KR; Worldwide Research and Development, Pfizer Inc., Cambridge, MA, USA., Litchfield J; Worldwide Research and Development, Pfizer Inc., Cambridge, MA, USA., McCarthy T; Worldwide Research and Development, Pfizer Inc., Cambridge, MA, USA., Carson RE; Department of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, CT, USA., Halldin C; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Karolinska University Hospital Solna, R5:02, 17176, Stockholm, Sweden.; Stockholm Health Care Services, Stockholm County Council, Stockholm, Sweden.
Publikováno v:
EJNMMI research [EJNMMI Res] 2022 Mar 04; Vol. 12 (1), pp. 13. Date of Electronic Publication: 2022 Mar 04.
Autor:
Moore TL; Department of Anatomy & Neurobiology, Boston University School of Medicine, Boston, MA, United States.; Center for Systems Neuroscience, Boston University, Boston, MA, United States., Young DA; Internal Medicine Research Unit Pfizer Worldwide Research, Development and Medical Pfizer Inc., Cambridge, MA, United States., Killiany RJ; Department of Anatomy & Neurobiology, Boston University School of Medicine, Boston, MA, United States.; Center for Systems Neuroscience, Boston University, Boston, MA, United States., Fonseca KR; Medicine Design, Pfizer Worldwide Research, Development and Medical Pfizer Inc., Cambridge, MA, United States., Volfson D; Internal Medicine Research Unit Pfizer Worldwide Research, Development and Medical Pfizer Inc., Cambridge, MA, United States., Gray DL; Internal Medicine Research Unit Pfizer Worldwide Research, Development and Medical Pfizer Inc., Cambridge, MA, United States., Balice-Gordon R; Internal Medicine Research Unit Pfizer Worldwide Research, Development and Medical Pfizer Inc., Cambridge, MA, United States., Kozak R; Internal Medicine Research Unit Pfizer Worldwide Research, Development and Medical Pfizer Inc., Cambridge, MA, United States.
Publikováno v:
Frontiers in aging neuroscience [Front Aging Neurosci] 2021 Nov 26; Vol. 13, pp. 757850. Date of Electronic Publication: 2021 Nov 26 (Print Publication: 2021).
D1 Agonist Improved Movement of Parkinsonian Nonhuman Primates with Limited Dyskinesia Side Effects.
Autor:
Young D, Popiolek M, Trapa P, Fonseca KR, Brevard J; Quanticare , Cambridge , Massachusetts 02139 , United States., Gray DL, Kozak R
Publikováno v:
ACS chemical neuroscience [ACS Chem Neurosci] 2020 Feb 19; Vol. 11 (4), pp. 560-566. Date of Electronic Publication: 2020 Feb 06.
Autor:
Chang C; Systems Modeling and Simulation Group, Pharmacokinetics, Dynamics and Metabolism, Medicine Design (C.C., C.L., T.S.M.), Neuroscience and Pain Research Unit (W.H., L.E.Z., M.A.S., K.A.W., C.A.S., B.M.C., A.D., J.B.T., P.V.), and Pharmacokinetics, Dynamics and Metabolism, Medicine Design (K.R.F., S.S.G., H.R., A.S.-B., J.L.), Worldwide Research and Development, Pfizer Inc., Cambridge, Massachusetts cheng.chang@pfizer.com., Fonseca KR; Systems Modeling and Simulation Group, Pharmacokinetics, Dynamics and Metabolism, Medicine Design (C.C., C.L., T.S.M.), Neuroscience and Pain Research Unit (W.H., L.E.Z., M.A.S., K.A.W., C.A.S., B.M.C., A.D., J.B.T., P.V.), and Pharmacokinetics, Dynamics and Metabolism, Medicine Design (K.R.F., S.S.G., H.R., A.S.-B., J.L.), Worldwide Research and Development, Pfizer Inc., Cambridge, Massachusetts., Li C; Systems Modeling and Simulation Group, Pharmacokinetics, Dynamics and Metabolism, Medicine Design (C.C., C.L., T.S.M.), Neuroscience and Pain Research Unit (W.H., L.E.Z., M.A.S., K.A.W., C.A.S., B.M.C., A.D., J.B.T., P.V.), and Pharmacokinetics, Dynamics and Metabolism, Medicine Design (K.R.F., S.S.G., H.R., A.S.-B., J.L.), Worldwide Research and Development, Pfizer Inc., Cambridge, Massachusetts., Horner W; Systems Modeling and Simulation Group, Pharmacokinetics, Dynamics and Metabolism, Medicine Design (C.C., C.L., T.S.M.), Neuroscience and Pain Research Unit (W.H., L.E.Z., M.A.S., K.A.W., C.A.S., B.M.C., A.D., J.B.T., P.V.), and Pharmacokinetics, Dynamics and Metabolism, Medicine Design (K.R.F., S.S.G., H.R., A.S.-B., J.L.), Worldwide Research and Development, Pfizer Inc., Cambridge, Massachusetts., Zawadzke LE; Systems Modeling and Simulation Group, Pharmacokinetics, Dynamics and Metabolism, Medicine Design (C.C., C.L., T.S.M.), Neuroscience and Pain Research Unit (W.H., L.E.Z., M.A.S., K.A.W., C.A.S., B.M.C., A.D., J.B.T., P.V.), and Pharmacokinetics, Dynamics and Metabolism, Medicine Design (K.R.F., S.S.G., H.R., A.S.-B., J.L.), Worldwide Research and Development, Pfizer Inc., Cambridge, Massachusetts., Salafia MA; Systems Modeling and Simulation Group, Pharmacokinetics, Dynamics and Metabolism, Medicine Design (C.C., C.L., T.S.M.), Neuroscience and Pain Research Unit (W.H., L.E.Z., M.A.S., K.A.W., C.A.S., B.M.C., A.D., J.B.T., P.V.), and Pharmacokinetics, Dynamics and Metabolism, Medicine Design (K.R.F., S.S.G., H.R., A.S.-B., J.L.), Worldwide Research and Development, Pfizer Inc., Cambridge, Massachusetts., Welch KA; Systems Modeling and Simulation Group, Pharmacokinetics, Dynamics and Metabolism, Medicine Design (C.C., C.L., T.S.M.), Neuroscience and Pain Research Unit (W.H., L.E.Z., M.A.S., K.A.W., C.A.S., B.M.C., A.D., J.B.T., P.V.), and Pharmacokinetics, Dynamics and Metabolism, Medicine Design (K.R.F., S.S.G., H.R., A.S.-B., J.L.), Worldwide Research and Development, Pfizer Inc., Cambridge, Massachusetts., Strick CA; Systems Modeling and Simulation Group, Pharmacokinetics, Dynamics and Metabolism, Medicine Design (C.C., C.L., T.S.M.), Neuroscience and Pain Research Unit (W.H., L.E.Z., M.A.S., K.A.W., C.A.S., B.M.C., A.D., J.B.T., P.V.), and Pharmacokinetics, Dynamics and Metabolism, Medicine Design (K.R.F., S.S.G., H.R., A.S.-B., J.L.), Worldwide Research and Development, Pfizer Inc., Cambridge, Massachusetts., Campbell BM; Systems Modeling and Simulation Group, Pharmacokinetics, Dynamics and Metabolism, Medicine Design (C.C., C.L., T.S.M.), Neuroscience and Pain Research Unit (W.H., L.E.Z., M.A.S., K.A.W., C.A.S., B.M.C., A.D., J.B.T., P.V.), and Pharmacokinetics, Dynamics and Metabolism, Medicine Design (K.R.F., S.S.G., H.R., A.S.-B., J.L.), Worldwide Research and Development, Pfizer Inc., Cambridge, Massachusetts., Gernhardt SS; Systems Modeling and Simulation Group, Pharmacokinetics, Dynamics and Metabolism, Medicine Design (C.C., C.L., T.S.M.), Neuroscience and Pain Research Unit (W.H., L.E.Z., M.A.S., K.A.W., C.A.S., B.M.C., A.D., J.B.T., P.V.), and Pharmacokinetics, Dynamics and Metabolism, Medicine Design (K.R.F., S.S.G., H.R., A.S.-B., J.L.), Worldwide Research and Development, Pfizer Inc., Cambridge, Massachusetts., Rong H; Systems Modeling and Simulation Group, Pharmacokinetics, Dynamics and Metabolism, Medicine Design (C.C., C.L., T.S.M.), Neuroscience and Pain Research Unit (W.H., L.E.Z., M.A.S., K.A.W., C.A.S., B.M.C., A.D., J.B.T., P.V.), and Pharmacokinetics, Dynamics and Metabolism, Medicine Design (K.R.F., S.S.G., H.R., A.S.-B., J.L.), Worldwide Research and Development, Pfizer Inc., Cambridge, Massachusetts., Sawant-Basak A; Systems Modeling and Simulation Group, Pharmacokinetics, Dynamics and Metabolism, Medicine Design (C.C., C.L., T.S.M.), Neuroscience and Pain Research Unit (W.H., L.E.Z., M.A.S., K.A.W., C.A.S., B.M.C., A.D., J.B.T., P.V.), and Pharmacokinetics, Dynamics and Metabolism, Medicine Design (K.R.F., S.S.G., H.R., A.S.-B., J.L.), Worldwide Research and Development, Pfizer Inc., Cambridge, Massachusetts., Liras J; Systems Modeling and Simulation Group, Pharmacokinetics, Dynamics and Metabolism, Medicine Design (C.C., C.L., T.S.M.), Neuroscience and Pain Research Unit (W.H., L.E.Z., M.A.S., K.A.W., C.A.S., B.M.C., A.D., J.B.T., P.V.), and Pharmacokinetics, Dynamics and Metabolism, Medicine Design (K.R.F., S.S.G., H.R., A.S.-B., J.L.), Worldwide Research and Development, Pfizer Inc., Cambridge, Massachusetts., Dounay A; Systems Modeling and Simulation Group, Pharmacokinetics, Dynamics and Metabolism, Medicine Design (C.C., C.L., T.S.M.), Neuroscience and Pain Research Unit (W.H., L.E.Z., M.A.S., K.A.W., C.A.S., B.M.C., A.D., J.B.T., P.V.), and Pharmacokinetics, Dynamics and Metabolism, Medicine Design (K.R.F., S.S.G., H.R., A.S.-B., J.L.), Worldwide Research and Development, Pfizer Inc., Cambridge, Massachusetts., Tuttle JB; Systems Modeling and Simulation Group, Pharmacokinetics, Dynamics and Metabolism, Medicine Design (C.C., C.L., T.S.M.), Neuroscience and Pain Research Unit (W.H., L.E.Z., M.A.S., K.A.W., C.A.S., B.M.C., A.D., J.B.T., P.V.), and Pharmacokinetics, Dynamics and Metabolism, Medicine Design (K.R.F., S.S.G., H.R., A.S.-B., J.L.), Worldwide Research and Development, Pfizer Inc., Cambridge, Massachusetts., Verhoest P; Systems Modeling and Simulation Group, Pharmacokinetics, Dynamics and Metabolism, Medicine Design (C.C., C.L., T.S.M.), Neuroscience and Pain Research Unit (W.H., L.E.Z., M.A.S., K.A.W., C.A.S., B.M.C., A.D., J.B.T., P.V.), and Pharmacokinetics, Dynamics and Metabolism, Medicine Design (K.R.F., S.S.G., H.R., A.S.-B., J.L.), Worldwide Research and Development, Pfizer Inc., Cambridge, Massachusetts., Maurer TS; Systems Modeling and Simulation Group, Pharmacokinetics, Dynamics and Metabolism, Medicine Design (C.C., C.L., T.S.M.), Neuroscience and Pain Research Unit (W.H., L.E.Z., M.A.S., K.A.W., C.A.S., B.M.C., A.D., J.B.T., P.V.), and Pharmacokinetics, Dynamics and Metabolism, Medicine Design (K.R.F., S.S.G., H.R., A.S.-B., J.L.), Worldwide Research and Development, Pfizer Inc., Cambridge, Massachusetts.
Publikováno v:
Molecular pharmacology [Mol Pharmacol] 2018 Aug; Vol. 94 (2), pp. 823-833. Date of Electronic Publication: 2018 May 31.
Autor:
McAllister LA; Pfizer Worldwide Research and Development , 610 Main Street , Cambridge , Massachusetts 02139 , United States., Butler CR; Pfizer Worldwide Research and Development , 610 Main Street , Cambridge , Massachusetts 02139 , United States., Mente S; Pfizer Worldwide Research and Development , 610 Main Street , Cambridge , Massachusetts 02139 , United States., O'Neil SV; Pfizer Worldwide Research and Development , 445 Eastern Point Road , Groton , Connecticut 06340 , United States., Fonseca KR; Pfizer Worldwide Research and Development , 610 Main Street , Cambridge , Massachusetts 02139 , United States., Piro JR; Pfizer Worldwide Research and Development , 610 Main Street , Cambridge , Massachusetts 02139 , United States., Cianfrogna JA; Pfizer Worldwide Research and Development , 445 Eastern Point Road , Groton , Connecticut 06340 , United States., Foley TL; Pfizer Worldwide Research and Development , 445 Eastern Point Road , Groton , Connecticut 06340 , United States., Gilbert AM; Pfizer Worldwide Research and Development , 445 Eastern Point Road , Groton , Connecticut 06340 , United States., Harris AR; Pfizer Worldwide Research and Development , 445 Eastern Point Road , Groton , Connecticut 06340 , United States., Helal CJ; Pfizer Worldwide Research and Development , 445 Eastern Point Road , Groton , Connecticut 06340 , United States., Johnson DS; Pfizer Worldwide Research and Development , 610 Main Street , Cambridge , Massachusetts 02139 , United States., Montgomery JI; Pfizer Worldwide Research and Development , 445 Eastern Point Road , Groton , Connecticut 06340 , United States., Nason DM; Pfizer Worldwide Research and Development , 445 Eastern Point Road , Groton , Connecticut 06340 , United States., Noell S; Pfizer Worldwide Research and Development , 445 Eastern Point Road , Groton , Connecticut 06340 , United States., Pandit J; Pfizer Worldwide Research and Development , 445 Eastern Point Road , Groton , Connecticut 06340 , United States., Rogers BN; Pfizer Worldwide Research and Development , 610 Main Street , Cambridge , Massachusetts 02139 , United States., Samad TA; Pfizer Worldwide Research and Development , 610 Main Street , Cambridge , Massachusetts 02139 , United States., Shaffer CL; Pfizer Worldwide Research and Development , 610 Main Street , Cambridge , Massachusetts 02139 , United States., da Silva RG; Pfizer Worldwide Research and Development , 445 Eastern Point Road , Groton , Connecticut 06340 , United States., Uccello DP; Pfizer Worldwide Research and Development , 445 Eastern Point Road , Groton , Connecticut 06340 , United States., Webb D; Pfizer Worldwide Research and Development , 610 Main Street , Cambridge , Massachusetts 02139 , United States., Brodney MA; Pfizer Worldwide Research and Development , 610 Main Street , Cambridge , Massachusetts 02139 , United States.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2018 Apr 12; Vol. 61 (7), pp. 3008-3026. Date of Electronic Publication: 2018 Mar 15.
Autor:
Sciabola S; Worldwide Medicinal Chemistry, Pfizer Global Research & Development, Neuroscience, 610 Main Street, Cambridge, MA 02139, USA., Goetz GH; Worldwide Medicinal Chemistry, Pfizer Global Research & Development, Groton Laboratories, Eastern Point Road, Groton, CT 06340, USA., Bai G; Worldwide Medicinal Chemistry, Pfizer Global Research & Development, Groton Laboratories, Eastern Point Road, Groton, CT 06340, USA., Rogers BN; Worldwide Medicinal Chemistry, Pfizer Global Research & Development, Neuroscience, 610 Main Street, Cambridge, MA 02139, USA., Gray DL; Worldwide Medicinal Chemistry, Pfizer Global Research & Development, Neuroscience, 610 Main Street, Cambridge, MA 02139, USA., Duplantier A; Worldwide Medicinal Chemistry, Pfizer Global Research & Development, Neuroscience, 610 Main Street, Cambridge, MA 02139, USA., Fonseca KR; Department of Pharmacokinetics, Dynamics and Metabolism, Pfizer Global Research and Development, Cambridge, MA 02139, USA., Vanase-Frawley MA; Worldwide Medicinal Chemistry, Pfizer Global Research & Development, Groton Laboratories, Eastern Point Road, Groton, CT 06340, USA., Kablaoui NM; Worldwide Medicinal Chemistry, Pfizer Global Research & Development, Neuroscience, 610 Main Street, Cambridge, MA 02139, USA. Electronic address: Natasha.M.Kablaoui@pfizer.com.
Publikováno v:
Bioorganic & medicinal chemistry [Bioorg Med Chem] 2016 Aug 15; Vol. 24 (16), pp. 3513-20. Date of Electronic Publication: 2016 May 31.
Autor:
Modi ME; Neuroscience and Pain Research Unit (M.E.M., M.J.M., D.L.B.), Department of Pharmacokinetics, Dynamics and Metabolism (K.R.F.), Global Biotherapeutics Technologies (E.F.), and Worldwide Medicinal Chemistry (N.M.K.), Worldwide Research and Development, Pfizer Inc., Cambridge, Massachusetts; Department of Pharmacokinetics, Dynamics and Metabolism, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut (A.D., S.O., M.V.-F.); and Biotherapuetics Pharmaceutical Research and Development, Worldwide Research and Development, Pfizer Inc., Andover, Massachusetts (H.M., R.D.)., Majchrzak MJ; Neuroscience and Pain Research Unit (M.E.M., M.J.M., D.L.B.), Department of Pharmacokinetics, Dynamics and Metabolism (K.R.F.), Global Biotherapeutics Technologies (E.F.), and Worldwide Medicinal Chemistry (N.M.K.), Worldwide Research and Development, Pfizer Inc., Cambridge, Massachusetts; Department of Pharmacokinetics, Dynamics and Metabolism, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut (A.D., S.O., M.V.-F.); and Biotherapuetics Pharmaceutical Research and Development, Worldwide Research and Development, Pfizer Inc., Andover, Massachusetts (H.M., R.D.)., Fonseca KR; Neuroscience and Pain Research Unit (M.E.M., M.J.M., D.L.B.), Department of Pharmacokinetics, Dynamics and Metabolism (K.R.F.), Global Biotherapeutics Technologies (E.F.), and Worldwide Medicinal Chemistry (N.M.K.), Worldwide Research and Development, Pfizer Inc., Cambridge, Massachusetts; Department of Pharmacokinetics, Dynamics and Metabolism, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut (A.D., S.O., M.V.-F.); and Biotherapuetics Pharmaceutical Research and Development, Worldwide Research and Development, Pfizer Inc., Andover, Massachusetts (H.M., R.D.)., Doran A; Neuroscience and Pain Research Unit (M.E.M., M.J.M., D.L.B.), Department of Pharmacokinetics, Dynamics and Metabolism (K.R.F.), Global Biotherapeutics Technologies (E.F.), and Worldwide Medicinal Chemistry (N.M.K.), Worldwide Research and Development, Pfizer Inc., Cambridge, Massachusetts; Department of Pharmacokinetics, Dynamics and Metabolism, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut (A.D., S.O., M.V.-F.); and Biotherapuetics Pharmaceutical Research and Development, Worldwide Research and Development, Pfizer Inc., Andover, Massachusetts (H.M., R.D.)., Osgood S; Neuroscience and Pain Research Unit (M.E.M., M.J.M., D.L.B.), Department of Pharmacokinetics, Dynamics and Metabolism (K.R.F.), Global Biotherapeutics Technologies (E.F.), and Worldwide Medicinal Chemistry (N.M.K.), Worldwide Research and Development, Pfizer Inc., Cambridge, Massachusetts; Department of Pharmacokinetics, Dynamics and Metabolism, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut (A.D., S.O., M.V.-F.); and Biotherapuetics Pharmaceutical Research and Development, Worldwide Research and Development, Pfizer Inc., Andover, Massachusetts (H.M., R.D.)., Vanase-Frawley M; Neuroscience and Pain Research Unit (M.E.M., M.J.M., D.L.B.), Department of Pharmacokinetics, Dynamics and Metabolism (K.R.F.), Global Biotherapeutics Technologies (E.F.), and Worldwide Medicinal Chemistry (N.M.K.), Worldwide Research and Development, Pfizer Inc., Cambridge, Massachusetts; Department of Pharmacokinetics, Dynamics and Metabolism, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut (A.D., S.O., M.V.-F.); and Biotherapuetics Pharmaceutical Research and Development, Worldwide Research and Development, Pfizer Inc., Andover, Massachusetts (H.M., R.D.)., Feyfant E; Neuroscience and Pain Research Unit (M.E.M., M.J.M., D.L.B.), Department of Pharmacokinetics, Dynamics and Metabolism (K.R.F.), Global Biotherapeutics Technologies (E.F.), and Worldwide Medicinal Chemistry (N.M.K.), Worldwide Research and Development, Pfizer Inc., Cambridge, Massachusetts; Department of Pharmacokinetics, Dynamics and Metabolism, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut (A.D., S.O., M.V.-F.); and Biotherapuetics Pharmaceutical Research and Development, Worldwide Research and Development, Pfizer Inc., Andover, Massachusetts (H.M., R.D.)., McInnes H; Neuroscience and Pain Research Unit (M.E.M., M.J.M., D.L.B.), Department of Pharmacokinetics, Dynamics and Metabolism (K.R.F.), Global Biotherapeutics Technologies (E.F.), and Worldwide Medicinal Chemistry (N.M.K.), Worldwide Research and Development, Pfizer Inc., Cambridge, Massachusetts; Department of Pharmacokinetics, Dynamics and Metabolism, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut (A.D., S.O., M.V.-F.); and Biotherapuetics Pharmaceutical Research and Development, Worldwide Research and Development, Pfizer Inc., Andover, Massachusetts (H.M., R.D.)., Darvari R; Neuroscience and Pain Research Unit (M.E.M., M.J.M., D.L.B.), Department of Pharmacokinetics, Dynamics and Metabolism (K.R.F.), Global Biotherapeutics Technologies (E.F.), and Worldwide Medicinal Chemistry (N.M.K.), Worldwide Research and Development, Pfizer Inc., Cambridge, Massachusetts; Department of Pharmacokinetics, Dynamics and Metabolism, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut (A.D., S.O., M.V.-F.); and Biotherapuetics Pharmaceutical Research and Development, Worldwide Research and Development, Pfizer Inc., Andover, Massachusetts (H.M., R.D.)., Buhl DL; Neuroscience and Pain Research Unit (M.E.M., M.J.M., D.L.B.), Department of Pharmacokinetics, Dynamics and Metabolism (K.R.F.), Global Biotherapeutics Technologies (E.F.), and Worldwide Medicinal Chemistry (N.M.K.), Worldwide Research and Development, Pfizer Inc., Cambridge, Massachusetts; Department of Pharmacokinetics, Dynamics and Metabolism, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut (A.D., S.O., M.V.-F.); and Biotherapuetics Pharmaceutical Research and Development, Worldwide Research and Development, Pfizer Inc., Andover, Massachusetts (H.M., R.D.)., Kablaoui NM; Neuroscience and Pain Research Unit (M.E.M., M.J.M., D.L.B.), Department of Pharmacokinetics, Dynamics and Metabolism (K.R.F.), Global Biotherapeutics Technologies (E.F.), and Worldwide Medicinal Chemistry (N.M.K.), Worldwide Research and Development, Pfizer Inc., Cambridge, Massachusetts; Department of Pharmacokinetics, Dynamics and Metabolism, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut (A.D., S.O., M.V.-F.); and Biotherapuetics Pharmaceutical Research and Development, Worldwide Research and Development, Pfizer Inc., Andover, Massachusetts (H.M., R.D.) Natasha.M.Kablaoui@pfizer.com.
Publikováno v:
The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2016 Aug; Vol. 358 (2), pp. 164-72. Date of Electronic Publication: 2016 May 23.