Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Fons van de Loo"'
Autor:
Nathalie Thielen, Margot Neefjes, Renske Wiegertjes, Guus van den Akker, Elly Vitters, Henk van Beuningen, Esmeralda Blaney Davidson, Marije Koenders, Peter van Lent, Fons van de Loo, Arjan van Caam, Peter van der Kraan
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 15, p 8124 (2021)
Osteoarthritis (OA) is a degenerative joint disease characterized by irreversible cartilage damage, inflammation and altered chondrocyte phenotype. Transforming growth factor-β (TGF-β) signaling via SMAD2/3 is crucial for blocking hypertrophy. The
Externí odkaz:
https://doaj.org/article/ec54bbf3e1b84177af6b95216d328b24
Autor:
Niels A. J. Cremers, Martijn H. J. van den Bosch, Stephanie van Dalen, Irene Di Ceglie, Giuliana Ascone, Fons van de Loo, Marije Koenders, Peter van der Kraan, Annet Sloetjes, Thomas Vogl, Johannes Roth, Edwin J. W. Geven, Arjen B. Blom, Peter L. E. M. van Lent
Publikováno v:
Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-15 (2017)
Abstract Background Monocytes are dominant cells present within the inflamed synovium during osteoarthritis (OA). In mice, two functionally distinct monocyte subsets are described: pro-inflammatory Ly6Chigh and patrolling Ly6Clow monocytes. Alarmins
Externí odkaz:
https://doaj.org/article/000ad2f4ec3f47dc9d28f7482a1ea756
Autor:
Marcos A. E. Cruz, Luco Rutten, Martijn Martens, Onno Arntz, Fons van de Loo, Elena Macías-Sánchez, Anat Akiva, Pietro Ciancaglini, Ana P. Ramos, Nico Sommerdijk
Matrix vesicles (MVs) are involved in the initial deposition of hydroxyapatite (HAp) during bone mineralization, but their mechanism of action is not yet fully understood.In vitrostudies propose two pathways by which MVs can trigger HAp precipitation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4b93722a8ffc7a25cc647170b41fb89
https://doi.org/10.1101/2023.05.09.539570
https://doi.org/10.1101/2023.05.09.539570
Autor:
Giuliana Ascone, Irene DI Ceglie, Ilze Bot, Fons van de Loo, Marije Koenders, Peter van der Kraan, Arjen Blom, Martijn van den Bosch, Peter van Lent
Publikováno v:
Cartilage, synovium and bone.
Publikováno v:
The Journal of Immunology. 192:201.16-201.16
Enhanced expression of Toll-like Receptor (TLR) 4 and its endogenous agonists in rheumatoid joints suggests involvement in rheumatoid arthritis (RA). We assessed therapeutic efficacy and downstream effects of TLR4 blockade in murine and humanized mod
Autor:
Louise Henningsson, Tove Eneljung, Ulf Lidberg, Fons van de Loo, Wim van den Berg, Inger Gjertsson
Publikováno v:
The Journal of Immunology. 182:50.21-50.21
Current treatments of rheumatoid arthritis are focused on suppression of the immune response irrespective of the inflammatory status. Interleukin (IL) -10 is a cytokine with anti-inflammatory properties. Lentiviral vectors has been used to insert an
Autor:
Davidson, E. N. Blaney, Caam, A. P., Vitters, E. L., Bennink, M. B., Thijssen, E., Den Berg, W. B., Koenders, M. I., Lent, P. L., Fons van de Loo, Kraan, P. M.
Publikováno v:
ResearcherID
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::642a02c15e8e6b51e71a1e21d4f7b423
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000355048800098&KeyUID=WOS:000355048800098
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000355048800098&KeyUID=WOS:000355048800098
Autor:
Broeren, M. G. A., Bennink, M. B., Arntz, O. J., Vermeij, E. A., Den Berg, W. B., Fons van de Loo
Publikováno v:
ResearcherID
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2a00b59daddfc11ce0a707443fe968aa
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000363878700180&KeyUID=WOS:000363878700180
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000363878700180&KeyUID=WOS:000363878700180
Autor:
Broeren, Mathijs G. A., Vermeij, Eline A., Bennink, Miranda B., Arntz, Onno J., Gjertsson, Inger, Den Berg, Wim B., Fons van de Loo
Publikováno v:
ResearcherID
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6babf8c28d9747d2e14d7442c78a56a9
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000344774700275&KeyUID=WOS:000344774700275
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000344774700275&KeyUID=WOS:000344774700275
Autor:
Praet, Jens, Donovan, Erin, Drennan, Michael, Fons van de Loo, Rabot, Sylvie, Raes, Jeroen, Wiele, Tom, Ware, Carl, Elewaut, Dirk
Publikováno v:
ResearcherID
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4d93737ae2b04fb140b94a09a0c52828
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000344384901182&KeyUID=WOS:000344384901182
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000344384901182&KeyUID=WOS:000344384901182