Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Fons Elstrodt"'
Autor:
Mieke Schutte, Fons Elstrodt, Linda B C Bralten, Jord H A Nagel, Elza Duijm, Antoinette Hollestelle, Maartje J Vuerhard, Marijke Wasielewski, Justine K Peeters, Peter van der Spek, Peter A Sillevis Smitt, Pim J French
Publikováno v:
PLoS ONE, Vol 3, Iss 8, p e3007 (2008)
BACKGROUND: Identification of genes that are causally implicated in oncogenesis is a major goal in cancer research. An estimated 10-20% of cancer-related gene mutations result in skipping of one or more exons in the encoded transcripts. Here we repor
Externí odkaz:
https://doaj.org/article/643fafb4ae6e4f71a382f8722e3eed19
Constitutive activation of the phosphatidylinositol-3-OH kinase (PI3K) and RAS signaling pathways are important events in tumor formation. This is illustrated by the frequent genetic alteration of several key players from these pathways in a wide var
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b287b7859454871c461b6235397b5dbd
https://doi.org/10.1158/1541-7786.c.6542854
https://doi.org/10.1158/1541-7786.c.6542854
Supplementary Table S1 from Phosphatidylinositol-3-OH Kinase or RAS Pathway Mutations in Human Breast Cancer Cell Lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68a8ad178a4ed3d94363839b181f40f7
https://doi.org/10.1158/1541-7786.22520968.v1
https://doi.org/10.1158/1541-7786.22520968.v1
Autor:
Mieke Schutte, Stephen P. Ethier, Sofia D. Merajver, Ans van den Ouweland, Marijke Wasielewski, Michael Gorin, Jord H.A. Nagel, Antoinette Hollestelle, Fons Elstrodt
Supplementary Figure S2 from BRCA1 Mutation Analysis of 41 Human Breast Cancer Cell Lines Reveals Three New Deleterious Mutants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d38f146bff03f6e00723fe52caced057
https://doi.org/10.1158/0008-5472.22365296.v1
https://doi.org/10.1158/0008-5472.22365296.v1
Autor:
Mieke Schutte, Stephen P. Ethier, Sofia D. Merajver, Ans van den Ouweland, Marijke Wasielewski, Michael Gorin, Jord H.A. Nagel, Antoinette Hollestelle, Fons Elstrodt
Germ line mutations of the BRCA1 gene confer a high risk of breast cancer and ovarian cancer to female mutation carriers. The BRCA1 protein is involved in the regulation of DNA repair. How specific tumor-associated mutations affect the molecular func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4225517ebd04c5032b1882b3e0473fb
https://doi.org/10.1158/0008-5472.c.6494630
https://doi.org/10.1158/0008-5472.c.6494630
Autor:
Mieke Schutte, Stephen P. Ethier, Sofia D. Merajver, Ans van den Ouweland, Marijke Wasielewski, Michael Gorin, Jord H.A. Nagel, Antoinette Hollestelle, Fons Elstrodt
Supplementary Figure Legends from BRCA1 Mutation Analysis of 41 Human Breast Cancer Cell Lines Reveals Three New Deleterious Mutants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::465d57e52d999e8354107e018b96ebf9
https://doi.org/10.1158/0008-5472.22365302
https://doi.org/10.1158/0008-5472.22365302
Autor:
Jan G. M. Klijn, Mieke Schutte, John A. Foekens, Fons Elstrodt, Antoinette Hollestelle, Anieta M. Sieuwerts, Mieke Timmermans, Michael A. den Bakker
Publikováno v:
Breast Cancer Research and Treatment, 122(1), 125-133. Springer New York
Mutations of E-cadherin have been identified in half of lobular breast cancers and diffuse-type gastric cancers, two tumor subtypes with remarkably similar pathological appearances including small rounded cells with scant cytoplasm and a diffuse grow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ee5cfd5c358e486d5c64f3dfd3cfcbf
https://doi.org/10.1007/s10549-009-0545-4
https://doi.org/10.1007/s10549-009-0545-4
Autor:
Anieta M. Sieuwerts, Jaco Kraan, Joan Bolt-De Vries, Petra Van Der Spoel, Fons Elstrodt, Marcel Smid, Mieke Timmermans, Bianca Mostert, Mieke Schutte, John W. M. Martens, Jan-Willem Gratama, Stefan Sleijfer, John A. Foekens
Publikováno v:
JNCI Journal of the National Cancer Institute
Journal of the National Cancer Institute, 101(12), 896-897. Oxford University Press
Journal of the National Cancer Institute, 101(1), 61-66. Oxford University Press
Journal of the National Cancer Institute, 101(12), 896-897. Oxford University Press
Journal of the National Cancer Institute, 101(1), 61-66. Oxford University Press
Identification of specific subtypes of circulating tumor cells in peripheral blood of cancer patients can provide information about the biology of metastasis and improve patient management. However, to be effective, the method used to identify circul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7638fc2ac688169355a680f94e1e0540
http://europepmc.org/articles/PMC2639293
http://europepmc.org/articles/PMC2639293
Publikováno v:
Breast Cancer Research and Treatment, 99(1), 97-101. Springer New York
The p53 tumor suppressor gene is frequently mutated in breast cancer. Here, we used direct sequencing to screen the complete coding sequence of the p53 gene from 41 human breast cancer cell lines. We identified 32 cell lines (78%) with a p53 gene alt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aba70b9e830094c6feba6697a4ac116
https://pure.eur.nl/en/publications/a2f68c57-2565-4b8a-9cb4-8f633526b638
https://pure.eur.nl/en/publications/a2f68c57-2565-4b8a-9cb4-8f633526b638
Autor:
M Molier, Mieke Schutte, Fons Elstrodt, Winand N.M. Dinjens, Els M.J.J. Berns, I C Harkes, Jan G. M. Klijn
Publikováno v:
British Journal of Cancer
Heterozygous loss of relatively large chromosomal regions is a hallmark of the inactivation of tumour suppressor genes. Searching for deletions in cancer genomes therefore provides an attractive option to identify new tumour suppressor genes. Here, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a25e069ef85a6ef59daafc75199554b5
https://doi.org/10.1038/sj.bjc.6601448
https://doi.org/10.1038/sj.bjc.6601448