Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Fons A.J. van de Loo"'
Autor:
Peter M. van der Kraan, Arjan P.M. van Caam, Esmeralda N. Blaney Davidson, Martijn H.J. van den Bosch, Fons A.J. van de Loo
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 6, Iss 2, Pp 100459- (2024)
Introduction: Articular cartilage makes smooth movement possible and destruction of this tissue leads to loss of joint function. An important biomolecule that determines this function is the large aggregating proteoglycan of cartilage, aggrecan. Aggr
Externí odkaz:
https://doaj.org/article/b72967b90e8945799f4440402ffa7eae
Autor:
Natália Valdrighi, Arjen B. Blom, Henk M. van Beuningen, Elly L. Vitters, Monique M. Helsen, Birgitte Walgreen, Peter L.E.M. van Lent, Marije I. Koenders, Peter M. van der Kraan, Fons A.J. van de Loo, Esmeralda N. Blaney Davidson
Publikováno v:
PeerJ, Vol 11, p e15482 (2023)
Background Osteoarthritis (OA) is a progressive joint disease and a major cause of chronic pain in adults. The prevalence of OA is higher in female patients, who tend to have worse OA outcomes, partially due to pain. The association between joint pai
Externí odkaz:
https://doaj.org/article/03fdaf6af3ba4d28bb9268a02e580afc
Autor:
Natália Valdrighi, Juliana P. Vago, Arjen B. Blom, Fons A.J. van de Loo, Esmeralda N. Blaney Davidson
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Osteoarthritis (OA) is a progressive whole-joint disease; no disease-modifying drugs are currently available to stop or slow its process. Symptoms alleviation is the only treatment option. OA is the major cause of chronic pain in adults, with pain be
Externí odkaz:
https://doaj.org/article/2b43ae5ca4644266b4a9397d3d698fc8
Autor:
Mathijs G.A. Broeren, Irene Di Ceglie, Miranda B. Bennink, Peter L.E.M. van Lent, Wim B. van den Berg, Marije I. Koenders, Esmeralda N. Blaney Davidson, Peter M. van der Kraan, Fons A.J. van de Loo
Publikováno v:
PeerJ, Vol 6, p e4771 (2018)
Objective Tumor necrosis factor-inducible gene 6 (TSG-6) has anti-inflammatory and chondroprotective effects in mouse models of inflammatory arthritis. Because cartilage damage and inflammation are also observed in osteoarthritis (OA), we determined
Externí odkaz:
https://doaj.org/article/e674760745904a79b44e5fdbcd6e3d74
Autor:
Eline A. Vermeij, Marije I. Koenders, Arjen B. Blom, Onno J. Arntz, Miranda B. Bennink, Wim B. van den Berg, Peter L.E.M. van Lent, Fons A.J. van de Loo
Publikováno v:
Molecular Imaging, Vol 13 (2014)
Rheumatoid arthritis (RA) and osteoarthritis (OA) are serologically and clinically distinctive, but at the local level, both diseases have many molecular pathways in common. In vivo molecular imaging can unravel the local pathologic processes involve
Externí odkaz:
https://doaj.org/article/28070d24be67493c9d7e39c91239ac85
Autor:
Christine Plater-Zyberk, Leo A.B. Joosten, Monique M.A. Helsen, Pascale Sattonnet-Roche, Christiane Siegfried, Sami Alouani, Fons A.J. van de Loo, Pierre Graber, Shuki Aloni, Rocco Cirillo, Erik Lubberts, Charles A. Dinarello, Wim B. van den Berg, Yolande Chvatchko
Publikováno v:
Journal of Clinical Investigation, 108, 12, pp. 1825-32
Journal of Clinical Investigation, 108, 1825-32
Journal of Clinical Investigation, 108, 1825-32
Contains fulltext : 134210.pdf (Publisher’s version ) (Open Access) Two distinct IL-18 neutralizing strategies, i.e. a rabbit polyclonal anti-mouse IL-18 IgG and a recombinant human IL-18 binding protein (rhIL-18BP), were used to treat collagen-ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff64ffa02aeabf47eea950d3ae82d11b
https://hdl.handle.net/2066/134210
https://hdl.handle.net/2066/134210
Publikováno v:
Mechanisms and Models in Rheumatoid Arthritis ISBN: 9780123404404
Mechanisms and Models in Rheumatoid Arthritis
Mechanisms and Models in Rheumatoid Arthritis
The cytokines IL-1 and TNF cannot by themselves account for the pathology of rheumatoid arthritis (RA) or osteoarthritis. Nonetheless, their actions mimic in detail many processes observed in arthritic disease, and circumstances that could lead to co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::654947fb33fd341cc3d54fada1812bc6
https://doi.org/10.1016/b978-012340440-4/50058-1
https://doi.org/10.1016/b978-012340440-4/50058-1