Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Fonnet E. Bleeker"'
Autor:
Willemina R. Geurts‐Giele, Efraim H. Rosenberg, Anja van Rens, Monique E. van Leerdam, Winand N. Dinjens, Fonnet E. Bleeker
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 7, Iss 7, Pp n/a-n/a (2019)
Abstract Background Lynch syndrome (LS) is caused by germline mismatch repair (MMR) gene mutations. De novo MMR gene mutations are rare, and somatic mosaicism in LS is thought to be infrequent. We describe the first case of somatic mosaicism by a de
Externí odkaz:
https://doaj.org/article/681c95df2cbd4164bbff6eacc946d574
Autor:
Vincent M. T. de Jong, Roelof Pruntel, Tessa G. Steenbruggen, Fonnet E. Bleeker, Petra Nederlof, Frans B. L. Hogervorst, Sabine C. linn
Publikováno v:
Familial Cancer. 22:151-154
An inherited single nucleotide variant (SNV) in the 5′UTR of the BRCA1 gene c.-107A > T was identified to be related to BRCA1 promoter hypermethylation and a hereditary breast and ovarian cancer phenotype in two UK families. We investigated whether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c0515b35de8ff1266b9d78602051e37
https://doi.org/10.1007/s10689-022-00314-z
https://doi.org/10.1007/s10689-022-00314-z
Autor:
Jaroslaw P. Maciejewski, Cornelis J.F. van Noorden, Mikkael A. Sekeres, Sudipto Mukherjee, Hetty E. Carraway, Johanna W. Wilmink, Fonnet E. Bleeker, Mingjiang Xu, Hideki Makishima, Bartolomiej Przychodzen, Mohammed Khurshed, Yasunobu Nagata, Tomas Radivoyevitch, Remco J. Molenaar
Supplementary Figures, Methods and Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ce1b389c2f5ace078c3ab4c156e3b4e
https://doi.org/10.1158/1078-0432.22465104
https://doi.org/10.1158/1078-0432.22465104
Autor:
Cornelis J. van Noorden, Fonnet E. Bleeker, William P. Leenders, W. Peter Vandertop, Jaroslaw P. Maciejewski, Johanna W. Wilmink, Tomas Radivoyevitch, Ron A. Hoebe, Cornelis M. van Drunen, Dionysia Dimitrakopoulou, Adri N. Mul, Krissie Lenting, Mohammed Khurshed, Peter Henneman, Jan Stap, Sanne A. van Lith, Vashendriya V. Hira, Myrthe A. Smits, Dennis Botman, Remco J. Molenaar
D-2HG inhibits IDH-mediated NADPH production capacity, but not G6PD-mediated NADPH production capacity or IDH-mediated NADH production capacity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c00fef62eafc6548de46176770adc97
https://doi.org/10.1158/0008-5472.22412280.v1
https://doi.org/10.1158/0008-5472.22412280.v1
Autor:
Jaroslaw P. Maciejewski, Cornelis J.F. van Noorden, Mikkael A. Sekeres, Sudipto Mukherjee, Hetty E. Carraway, Johanna W. Wilmink, Fonnet E. Bleeker, Mingjiang Xu, Hideki Makishima, Bartolomiej Przychodzen, Mohammed Khurshed, Yasunobu Nagata, Tomas Radivoyevitch, Remco J. Molenaar
Purpose: Somatic mutations in IDH1/2 occur in approximately 20% of patients with myeloid neoplasms, including acute myeloid leukemia (AML). IDH1/2MUT enzymes produce D-2-hydroxyglutarate (D2HG), which associates with increased DNA damage and improved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d3061937fbbcd1a034d5fd53c111a94
https://doi.org/10.1158/1078-0432.c.6525927.v1
https://doi.org/10.1158/1078-0432.c.6525927.v1
Autor:
Cornelis J. van Noorden, Fonnet E. Bleeker, William P. Leenders, W. Peter Vandertop, Jaroslaw P. Maciejewski, Johanna W. Wilmink, Tomas Radivoyevitch, Ron A. Hoebe, Cornelis M. van Drunen, Dionysia Dimitrakopoulou, Adri N. Mul, Krissie Lenting, Mohammed Khurshed, Peter Henneman, Jan Stap, Sanne A. van Lith, Vashendriya V. Hira, Myrthe A. Smits, Dennis Botman, Remco J. Molenaar
SPSS output statistics for comparisons between survival curves from colony-formation assays.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20d1222c3980f828fe4ee1f14a765f79
https://doi.org/10.1158/0008-5472.22412268.v1
https://doi.org/10.1158/0008-5472.22412268.v1
Autor:
Cornelis J. van Noorden, Fonnet E. Bleeker, William P. Leenders, W. Peter Vandertop, Jaroslaw P. Maciejewski, Johanna W. Wilmink, Tomas Radivoyevitch, Ron A. Hoebe, Cornelis M. van Drunen, Dionysia Dimitrakopoulou, Adri N. Mul, Krissie Lenting, Mohammed Khurshed, Peter Henneman, Jan Stap, Sanne A. van Lith, Vashendriya V. Hira, Myrthe A. Smits, Dennis Botman, Remco J. Molenaar
Isocitrate dehydrogenase 1 (IDH1) is mutated in various types of human cancer to IDH1R132H, a structural alteration that leads to catalysis of α-ketoglutarate to the oncometabolite D-2-hydroxyglutarate. In this study, we present evidence that small-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5c1fa1f1ef7af279dc9e5e587d4809e
https://doi.org/10.1158/0008-5472.c.6508407.v1
https://doi.org/10.1158/0008-5472.c.6508407.v1
Autor:
Pim J. French, Martin J. van den Bent, Peter A.E. Sillevis Smitt, Johan M. Kros, Peter J. van der Spek, Paul H.C. Eilers, Bart De Moor, Nanne K. Kloosterhof, Linda B.C. Bralten, Fonnet E. Bleeker, Anneleen Daemen, J. Elza Duijm, Andrew P. Stubbs, Johan J. de Rooi, Olivier Gevaert, Mathilde C.M. Kouwenhoven, Lonneke A.M. Gravendeel
Supplementary Figure 5 from Intrinsic Gene Expression Profiles of Gliomas Are a Better Predictor of Survival than Histology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2484d715b6cc7ba67a3f920e458b400
https://doi.org/10.1158/0008-5472.22383066.v1
https://doi.org/10.1158/0008-5472.22383066.v1
Autor:
Pim J. French, Martin J. van den Bent, Peter A.E. Sillevis Smitt, Johan M. Kros, Peter J. van der Spek, Paul H.C. Eilers, Bart De Moor, Nanne K. Kloosterhof, Linda B.C. Bralten, Fonnet E. Bleeker, Anneleen Daemen, J. Elza Duijm, Andrew P. Stubbs, Johan J. de Rooi, Olivier Gevaert, Mathilde C.M. Kouwenhoven, Lonneke A.M. Gravendeel
Supplementary Figure 10 from Intrinsic Gene Expression Profiles of Gliomas Are a Better Predictor of Survival than Histology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23eb937e4bff1d54542ea3caf1003fa4
https://doi.org/10.1158/0008-5472.22383078.v1
https://doi.org/10.1158/0008-5472.22383078.v1
Autor:
Pim J. French, Martin J. van den Bent, Peter A.E. Sillevis Smitt, Johan M. Kros, Peter J. van der Spek, Paul H.C. Eilers, Bart De Moor, Nanne K. Kloosterhof, Linda B.C. Bralten, Fonnet E. Bleeker, Anneleen Daemen, J. Elza Duijm, Andrew P. Stubbs, Johan J. de Rooi, Olivier Gevaert, Mathilde C.M. Kouwenhoven, Lonneke A.M. Gravendeel
Supplementary Figure 6 from Intrinsic Gene Expression Profiles of Gliomas Are a Better Predictor of Survival than Histology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57e0c19843b8a09d3260a3454d4b9956
https://doi.org/10.1158/0008-5472.22383063
https://doi.org/10.1158/0008-5472.22383063