Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Fong T. Bell"'
Publikováno v:
Stem Cell Research, Vol 16, Iss 2, Pp 252-255 (2016)
Parental origin-dependent expression of the imprinted genes is essential for mammalian development. Zfp57 maintains genomic imprinting in mouse embryos and ES cells. To examine the allelic expression patterns of the imprinted genes in ES cells, we ob
Externí odkaz:
https://doaj.org/article/291ef4cc05c3418ebacef18778dbcf5f
Autor:
Lizhi Liu, Shi-Qing Mao, Chelsea Ray, Yu Zhang, Fong T. Bell, Sheau-Fang Ng, Guo-Liang Xu, Xiajun Li
Publikováno v:
Stem Cell Research, Vol 15, Iss 2, Pp 435-443 (2015)
TET proteins have been found to play an important role in active demethylation at CpG sites in mammals. There are some reports implicating their functions in removal of DNA methylation imprint at the imprinted regions in the germline. However, it is
Externí odkaz:
https://doaj.org/article/6d8f02cc03004a0580a887e4e35bae81
Publikováno v:
Stem Cell Research, Vol 16, Iss 2, Pp 252-255 (2016)
Parental origin-dependent expression of the imprinted genes is essential for mammalian development. Zfp57 maintains genomic imprinting in mouse embryos and ES cells. To examine the allelic expression patterns of the imprinted genes in ES cells, we ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66a13a474a10f4ec31c41849ca0f5203
https://doi.org/10.1016/j.scr.2016.01.017
https://doi.org/10.1016/j.scr.2016.01.017
Publikováno v:
Epigenetics. 8:1268-1279
Genomic imprinting is a common epigenetic phenomenon in mammals. Dysregulation of genomic imprinting has been implicated in a variety of human diseases. ZFP57 is a master regulator in genomic imprinting. Loss of ZFP57 causes loss of DNA methylation i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b8229f914c9ac8dec16397e93663542
https://doi.org/10.4161/epi.26544
https://doi.org/10.4161/epi.26544
Autor:
Carol M. McDonald, Michael Kyba, Ho-Tak Lau, Dana E. Cullen, Monica Andrade, Jipo Sheng, Xiajun Li, Guoliang Xu, Fong T. Bell, Michelina Iacovino, Xiaopan Zuo
Publikováno v:
Journal of Biological Chemistry. 287:2107-2118
Previously, we discovered that ZFP57 is a maternal-zygotic effect gene, and it maintains DNA methylation genomic imprint at multiple imprinted regions in mouse embryos. Despite these findings, it remains elusive how DNA methyltransferases are targete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bec26bda26c677152c800918ad3e4077
https://doi.org/10.1074/jbc.m111.322644
https://doi.org/10.1074/jbc.m111.322644
Autor:
Yu Zhang, Shi-Qing Mao, Chelsea Ray, Lizhi Liu, Sheau-Fang Ng, Xiajun Li, Fong T. Bell, Guoliang Xu
Publikováno v:
Stem Cell Research, Vol 15, Iss 2, Pp 435-443 (2015)
TET proteins have been found to play an important role in active demethylation at CpG sites in mammals. There are some reports implicating their functions in removal of DNA methylation imprint at the imprinted regions in the germline. However, it is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dcfe5b60ee5f3b7d2da518e7a7e346b
https://europepmc.org/articles/PMC4618460/
https://europepmc.org/articles/PMC4618460/
Autor:
Lizhi Liu, Xiao Yang, Sachiko Takikawa, Sheau-Fang Ng, Yulia Shamis, Xiajun Li, Chelsea Ray, Ivan P. Moskowitz, Fong T. Bell, Dana E. Cullen, Lijuan Xiao, Chen-Leng Cai, Guan Yang
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 112(16)
Zfp57 is a maternal–zygotic effect gene that maintains genomic imprinting. Here we report that Zfp57 mutants exhibited a variety of cardiac defects including atrial septal defect (ASD), ventricular septal defect (VSD), thin myocardium, and reduced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bed0ad6415b3435214079de1a431c14f
https://pubmed.ncbi.nlm.nih.gov/25848000
https://pubmed.ncbi.nlm.nih.gov/25848000