Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Fonda M, Newcomb"'
Autor:
David A. Davis, Henry M. Fales, Fonda M. Newcomb, Kara M. Pearson, Elizabeth Read-Connole, Robert Yarchoan, Jackob Moskovitz
Publikováno v:
Antimicrobial Agents and Chemotherapy. 46:402-408
Previous studies have indicated that human immunodeficiency virus type 1 (HIV-1) protease inhibitors (PIs) are less active at blocking viral replication in HIV-1 infected peripheral blood monocytes/macrophages (M/M) than in HIV-1-infected T cells. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c5613234bae03b20ac27b6a9a96860e
https://doi.org/10.1128/aac.46.2.402-408.2002
https://doi.org/10.1128/aac.46.2.402-408.2002
Autor:
Fonda M. Newcomb, Ellen Feigal, Giovanna Tosato, William D. Figg, Denise Whitby, James M. Pluda, Robert Yarchoan, Vickie Marshall, Kathleen M. Wyvill, Seth M. Steinberg, Richard F. Little, James J. Goedert, Lauri Welles
Publikováno v:
Journal of Clinical Oncology. 18:2593-2602
PURPOSE: To assess the toxicity and activity of oral thalidomide in Kaposi’s sarcoma (KS) in a phase II dose-escalation study. PATIENTS AND METHODS: Human immunodeficiency virus (HIV)–seropositive patients with biopsy-confirmed KS that progressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99aaead43a09d197290ec43d9eef1d7a
https://doi.org/10.1200/jco.2000.18.13.2593
https://doi.org/10.1200/jco.2000.18.13.2593
Autor:
David A. Davis, Henry M. Fales, Paul T. Wingfield, Joshua Kaufman, Fonda M. Newcomb, Stephen J. Stahl, Robert Yarchoan, Jackob Moskovitz, Rodney L. Levine
Publikováno v:
Biochemical Journal. 346:305-311
Human immunodeficiency viruses encode a homodimeric protease that is essential for the production of infectious virus. Previous studies have shown that HIV-1 protease is susceptible to oxidative inactivation at the dimer interface at Cys-95, a proces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cfd578ab5c159c5e9f7de2aeaf13dfe
https://doi.org/10.1042/bj3460305
https://doi.org/10.1042/bj3460305
Autor:
Thomas R. O'Brien, Goedert Jj, Fonda M. Newcomb, R. Yarchoan, Sharon E. Straus, MW Saville, R. W. Humphrey, GA Ramos, H Nishihara, Kathy Wyvill
Publikováno v:
Blood. 88:297-301
Herpesvirus-like DNA sequences (KSHV/HHV-8) have recently been described in AIDS-associated Kaposi's sarcoma (KS) lesions. Many questions remain regarding the role of this virus in KS and the therapeutic implications of this finding. In the current s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38ff4157f18aca782cccf4923baaf75d
https://doi.org/10.1182/blood.v88.1.297.297
https://doi.org/10.1182/blood.v88.1.297.297
Autor:
David A, Davis, Fonda M, Newcomb, Jackob, Moskovitz, Henry M, Fales, Rodney L, Levine, Robert, Yarchoan
Publikováno v:
Methods in enzymology. 348
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4e4332f032c961d03f1fcf2b1f463753
https://pubmed.ncbi.nlm.nih.gov/11885278
https://pubmed.ncbi.nlm.nih.gov/11885278
Autor:
Rodney L. Levine, Henry M. Fales, Fonda M. Newcomb, Robert Yarchoan, Jackob Moskovitz, David A. Davis
Publisher Summary The enzyme HIV-2 protease contains two conserved methionine residues. Although methionine is generally not considered a conservative substitute for cysteine, both amino acids are susceptible to oxidative modification and, therefore,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c499c6420ff8535c2c400d2b1ea47a9b
https://doi.org/10.1016/s0076-6879(02)48643-0
https://doi.org/10.1016/s0076-6879(02)48643-0
Autor:
Robert Yarchoan, Hiroaki Mitsuya, Fonda M. Newcomb, Laura A. Gillim, David A. Davis, Keisuke Yusa
Publikováno v:
Journal of virology. 73(2)
We investigated the role of the two highly conserved cysteine residues, cysteines 67 and 95, of the human immunodeficiency virus type 1 (HIV-1) protease in regulating the activity of that protease during viral maturation. To this end, we generated fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6403941f8ac5e1ce1b01f5b95a2d9e8e
https://pubmed.ncbi.nlm.nih.gov/9882317
https://pubmed.ncbi.nlm.nih.gov/9882317
Publikováno v:
Leukemialymphoma. 28(3-4)
The discovery of Kaposi's Sarcoma-associated herpesvirus/human herpesvirus-8 (KSHV/ HHV-8) and subsequent studies of this virus have provided a body of evidence that support the concept that this is an etiologic agent for Kaposi's sarcoma (KS). Sever
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2d39a622b0e3735bb46687f2f9b839d
https://pubmed.ncbi.nlm.nih.gov/9517497
https://pubmed.ncbi.nlm.nih.gov/9517497
Autor:
David E. Ott, John J. Mieyal, Fonda M. Newcomb, David A. Davis, David W. Starke, Robert Yarchoan
Publikováno v:
The Journal of biological chemistry. 272(41)
Previous studies have suggested that the two conserved cysteines of the HIV-1 protease may be involved in regulating protease activity. Here, we examined diglutathionylated wild type protease (Cys-67-SSG, Cys-95-SSG) and the monoglutathionylated prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ed342f80f85f04a4fb6a7ef3660d1d6
https://pubmed.ncbi.nlm.nih.gov/9325327
https://pubmed.ncbi.nlm.nih.gov/9325327
Autor:
R. W. Humphrey, Thomas R. O'Brien, Sharon E. Straus, Fonda M. Newcomb, David A. Davis, James J. Goedert, Robert Yarchoan
Publikováno v:
The Journal of infectious diseases. 175(5)
Kaposi's sarcoma (KS)-associated herpesvirus/human herpesvirus type 8 (KSHV/HHV-8) may play an etiologic role in the pathogenesis of KS. In an attempt to assess KSHV/HHV-8 infection, an ELISA was developed using an 18-amino acid peptide from a putati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::103c92d3e35822af29e185cc7a6b015c
https://pubmed.ncbi.nlm.nih.gov/9129068
https://pubmed.ncbi.nlm.nih.gov/9129068