Epigenetic remodeling in B-cell acute lymphoblastic leukemia occurs in two tracks and employs embryonic stem cell-like signatures

Autor: Wiemels, Joseph, Wiencke, John, Wrensch, Margaret, Lee, ST, Muench, MO, Fomin, ME, Xiao, J, Zhou, M, De, A, Martín-Subero, JI, Heath, S, Houseman, EA, Roy, R

Publikováno v: Wiemels, Joseph; Wiencke, John; Wrensch, Margaret; Lee, ST; Muench, MO; Fomin, ME; et al.(2015). Epigenetic remodeling in B-cell acute lymphoblastic leukemia occurs in two tracks and employs embryonic stem cell-like signatures. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/1hq4b041

© The Author(s) 2015.We investigated DNA methylomes of pediatric Bcell acute lymphoblastic leukemias (B-ALLs) using whole-genome bisulfite sequencing and highdefinition microarrays, along with RNA expression profiles. Epigenetic alteration of B-ALLs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::7575e1520f15949ae7b038afe42a3980
http://www.escholarship.org/uc/item/1hq4b041

CD203c is expressed by human fetal hepatoblasts and distinguishes subsets of hepatoblastoma.

Autor: Muench MO; Vitalant Research Institute, San Francisco, CA, United States.; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA, United States., Fomin ME; Vitalant Research Institute, San Francisco, CA, United States., Gutierrez AG; Vitalant Research Institute, San Francisco, CA, United States., López-Terrada D; Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX, United States.; Texas Children's Cancer Center, Texas Children's Hospital, Houston, TX, United States., Gilfanova R; Vitalant Research Institute, San Francisco, CA, United States., Nosworthy C; Vitalant Research Institute, San Francisco, CA, United States., Beyer AI; Vitalant Research Institute, San Francisco, CA, United States., Ostolaza G; Vitalant Research Institute, San Francisco, CA, United States., Kats D; Pediatric Cancer Biology, Children's Cancer Therapy Development Institute, Beaverton, OR, United States., Matlock KL; Omics Data Automation, Beaverton, OR, United States., Cairo S; Research and Development Unit, XenTech, Evry, France., Keller C; Pediatric Cancer Biology, Children's Cancer Therapy Development Institute, Beaverton, OR, United States.

Publikováno v: Frontiers in oncology [Front Oncol] 2023 Feb 09; Vol. 13, pp. 927852. Date of Electronic Publication: 2023 Feb 09 (Print Publication: 2023).

The human chorion contains definitive hematopoietic stem cells from the fifteenth week of gestation.

Autor: Muench MO; Blood Systems Research Institute, San Francisco, CA 94118, USA.; Department of Laboratory Medicine, University of California, San Francisco, CA 94143, USA., Kapidzic M; The Ely and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, CA 94143, USA.; Center of Reproductive Sciences, Department of Obstetrics, Gynecology & Reproductive Sciences, University of California, San Francisco, CA 94143, USA., Gormley M; The Ely and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, CA 94143, USA.; Center of Reproductive Sciences, Department of Obstetrics, Gynecology & Reproductive Sciences, University of California, San Francisco, CA 94143, USA., Gutierrez AG; The Ely and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, CA 94143, USA.; Center of Reproductive Sciences, Department of Obstetrics, Gynecology & Reproductive Sciences, University of California, San Francisco, CA 94143, USA., Ponder KL; The Ely and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, CA 94143, USA.; Department of Pediatrics, University of California, San Francisco, CA 94143, USA., Fomin ME; Blood Systems Research Institute, San Francisco, CA 94118, USA., Beyer AI; Blood Systems Research Institute, San Francisco, CA 94118, USA., Stolp H; The Ely and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, CA 94143, USA.; Center of Reproductive Sciences, Department of Obstetrics, Gynecology & Reproductive Sciences, University of California, San Francisco, CA 94143, USA., Qi Z; Department of Laboratory Medicine, Clinical Cytogenetics Laboratory, University of California, San Francisco, CA 94107, USA., Fisher SJ; The Ely and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, CA 94143, USA.; Center of Reproductive Sciences, Department of Obstetrics, Gynecology & Reproductive Sciences, University of California, San Francisco, CA 94143, USA., Bárcena A; The Ely and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, CA 94143, USA Alicia.Barcena@ucsf.edu.; Center of Reproductive Sciences, Department of Obstetrics, Gynecology & Reproductive Sciences, University of California, San Francisco, CA 94143, USA.

Publikováno v: Development (Cambridge, England) [Development] 2017 Apr 15; Vol. 144 (8), pp. 1399-1411. Date of Electronic Publication: 2017 Mar 02.

Reduced alloimmunization in mice following repeated transfusion with pathogen-reduced platelets.

Autor: Muench MO; Blood Systems Research Institute.; Department of Laboratory Medicine, University of California, San Francisco, California., Heitman JW; Blood Systems Research Institute., Inglis H; Blood Systems Research Institute., Fomin ME; Blood Systems Research Institute., Marschner S; Department of Medicine, University of California, San Francisco, California., Goodrich RP; Department of Medicine, University of California, San Francisco, California., Norris PJ; Blood Systems Research Institute.; Department of Laboratory Medicine, University of California, San Francisco, California.; Terumo BCT Biotechnologies, Lakewood, Colorado., Jackman RP; Blood Systems Research Institute.; Department of Laboratory Medicine, University of California, San Francisco, California.

Publikováno v: Transfusion [Transfusion] 2016 Jun; Vol. 56 (6), pp. 1419-29. Date of Electronic Publication: 2016 Mar 29.

Neutralizing Monoclonal Antibodies Block Chikungunya Virus Entry and Release by Targeting an Epitope Critical to Viral Pathogenesis.

Autor: Jin J; Blood Systems Research Institute, San Francisco, CA 94118, USA; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA., Liss NM; Blood Systems Research Institute, San Francisco, CA 94118, USA; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA., Chen DH; Department of Structural Biology, Stanford University, Stanford, CA 94305, USA., Liao M; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA., Fox JM; Departments of Medicine, Molecular Microbiology, Pathology & Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA., Shimak RM; Departments of Medicine, Molecular Microbiology, Pathology & Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA., Fong RH; Integral Molecular Inc., Philadelphia, PA 19104, USA., Chafets D; Blood Systems Research Institute, San Francisco, CA 94118, USA; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA., Bakkour S; Blood Systems Research Institute, San Francisco, CA 94118, USA; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA., Keating S; Blood Systems Research Institute, San Francisco, CA 94118, USA; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA., Fomin ME; Blood Systems Research Institute, San Francisco, CA 94118, USA; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA., Muench MO; Blood Systems Research Institute, San Francisco, CA 94118, USA; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA., Sherman MB; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555, USA., Doranz BJ; Integral Molecular Inc., Philadelphia, PA 19104, USA., Diamond MS; Departments of Medicine, Molecular Microbiology, Pathology & Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA., Simmons G; Blood Systems Research Institute, San Francisco, CA 94118, USA; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address: gsimmons@bloodsystems.org.

Publikováno v: Cell reports [Cell Rep] 2015 Dec 22; Vol. 13 (11), pp. 2553-2564. Date of Electronic Publication: 2015 Dec 10.