Iron acquisition by a commensal bacterium modifies host nutritional immunity during Salmonella infection.

Autor: Spiga L; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Vanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University Medical Center, Nashville, TN 37232, USA., Fansler RT; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Vanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University Medical Center, Nashville, TN 37232, USA., Perera YR; Departments of Biochemistry and Chemistry and Center for Structural Biology, Vanderbilt University, Nashville, TN 37232, USA., Shealy NG; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Vanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University Medical Center, Nashville, TN 37232, USA., Munneke MJ; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Vanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University Medical Center, Nashville, TN 37232, USA., David HE; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Vanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University Medical Center, Nashville, TN 37232, USA., Torres TP; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA., Lemoff A; Department of Biochemistry, UT Southwestern Medical Center, Dallas, TX 75390, USA., Ran X; Departments of Chemistry, Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN 37232, USA., Richardson KL; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA., Pudlo N; Department of Microbiology & Immunology, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Martens EC; Department of Microbiology & Immunology, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Folta-Stogniew E; Keck Foundation Biotechnology Resource Laboratory, Yale University, 300 George Street, New Haven, CT 06511, USA., Yang ZJ; Departments of Chemistry, Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN 37232, USA., Skaar EP; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Vanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University Medical Center, Nashville, TN 37232, USA., Byndloss MX; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Vanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University Medical Center, Nashville, TN 37232, USA., Chazin WJ; Departments of Biochemistry and Chemistry and Center for Structural Biology, Vanderbilt University, Nashville, TN 37232, USA. Electronic address: walter.j.chazin@vanderbilt.edu., Zhu W; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Vanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University Medical Center, Nashville, TN 37232, USA. Electronic address: wenhan.zhu@vumc.org.

Publikováno v: Cell host & microbe [Cell Host Microbe] 2023 Oct 11; Vol. 31 (10), pp. 1639-1654.e10. Date of Electronic Publication: 2023 Sep 29.

Genetic or therapeutic neutralization of ALK1 reduces LDL transcytosis and atherosclerosis in mice.

Autor: Lee S; Department of Pharmacology, Yale University School of Medicine, New Haven, CT, USA.; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT, USA., Schleer H; Genovac Antibody Discovery, Fargo, ND, USA., Park H; Department of Internal Medicine, Cardiovascular Research Center, Yale University School of Medicine, New Haven, CT, USA.; Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT, USA., Jang E; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto, Ontario, Canada., Boyer M; Department of Pharmacology, Yale University School of Medicine, New Haven, CT, USA.; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT, USA., Tao B; Department of Pharmacology, Yale University School of Medicine, New Haven, CT, USA.; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT, USA., Gamez-Mendez A; Department of Pharmacology, Yale University School of Medicine, New Haven, CT, USA.; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT, USA., Singh A; Department of Pharmacology, Yale University School of Medicine, New Haven, CT, USA.; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT, USA., Folta-Stogniew E; W.M. Keck Biotechnology Resource Laboratory, Yale University School of Medicine, New Haven, CT, USA., Zhang X; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT, USA.; Department of Comparative Medicine, Yale University School of Medicine, New Haven, CT, USA., Qin L; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT, USA., Xiao X; Quantitative Biomedical Research Center, Department of Population & Data Sciences, University of Texas Southwestern Medical Center, Dallas, TX, USA., Xu L; Quantitative Biomedical Research Center, Department of Population & Data Sciences, University of Texas Southwestern Medical Center, Dallas, TX, USA., Zhang J; Department of Genetics, Yale University School of Medicine, New Haven, CT, USA., Hu X; Yale Cardiovascular Research Center, Department of Internal Medicine, Yale University, School of Medicine, New Haven, CT, USA., Pashos E; Internal Medicine Research, Unit Pfizer Inc., Cambridge, MA, USA., Tellides G; Department of Surgery, Yale University School of Medicine, New Haven, CT, USA., Shaul PW; Center for Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA., Lee WL; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto, Ontario, Canada., Fernandez-Hernando C; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT, USA.; Department of Comparative Medicine, Yale University School of Medicine, New Haven, CT, USA., Eichmann A; Department of Internal Medicine, Cardiovascular Research Center, Yale University School of Medicine, New Haven, CT, USA.; Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT, USA., Sessa WC; Department of Pharmacology, Yale University School of Medicine, New Haven, CT, USA. William.sessa@yale.edu.; Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT, USA. William.sessa@yale.edu.; Internal Medicine Research, Unit Pfizer Inc., Cambridge, MA, USA. William.sessa@yale.edu.

Publikováno v: Nature cardiovascular research [Nat Cardiovasc Res] 2023 May; Vol. 2 (5), pp. 438-448. Date of Electronic Publication: 2023 May 11.

Tuning protein half-life in mouse using sequence-defined biopolymers functionalized with lipids.

Autor: Vanderschuren K; Department of Molecular, Cellular & Developmental Biology, Yale University, New Haven, CT 06520.; Systems Biology Institute, Yale University, West Haven, CT 06516., Arranz-Gibert P; Department of Molecular, Cellular & Developmental Biology, Yale University, New Haven, CT 06520.; Systems Biology Institute, Yale University, West Haven, CT 06516., Khang M; Department of Biomedical Engineering, Yale University, New Haven, CT 06520., Hadar D; Avram and Stella Goldstein-Goren Department of Biotechnology Engineering, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel., Gaudin A; Department of Biomedical Engineering, Yale University, New Haven, CT 06520., Yang F; Department of Biomedical Engineering, Yale University, New Haven, CT 06520., Folta-Stogniew E; W. M. Keck Biotechnology Research Laboratory, Yale University School of Medicine, New Haven, CT 06511., Saltzman WM; Department of Biomedical Engineering, Yale University, New Haven, CT 06520.; Department of Chemical & Environmental Engineering, Yale University, New Haven, CT 06520.; Department of Cellular & Molecular Physiology, Yale University, New Haven, CT 06511., Amiram M; Avram and Stella Goldstein-Goren Department of Biotechnology Engineering, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel; mamiram@bgu.ac.il farren.isaacs@yale.edu., Isaacs FJ; Department of Molecular, Cellular & Developmental Biology, Yale University, New Haven, CT 06520; mamiram@bgu.ac.il farren.isaacs@yale.edu.; Systems Biology Institute, Yale University, West Haven, CT 06516.; Department of Biomedical Engineering, Yale University, New Haven, CT 06520.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Jan 25; Vol. 119 (4).

The Thermodynamic and Kinetic Properties of the dA-rU DNA-RNA Hybrid Base Pair Investigated via Molecular Dynamics Simulations.

Autor: Liu, Taigang¹ (AUTHOR) liuttgg@whu.edu.cn, Bao, Lei² (AUTHOR) bolly@whu.edu.cn, Wang, Yujie³ (AUTHOR) scuwangyujie@126.com

Publikováno v: Molecules. Oct2024, Vol. 29 Issue 20, p4920. 10p.

Insights into Transient Dimerisation of Carnitine/Acylcarnitine Carrier (SLC25A20) from Sarkosyl/PAGE, Cross-Linking Reagents, and Comparative Modelling Analysis.

Autor: Giangregorio, Nicola¹ (AUTHOR) a.tonazzi@ibiom.cnr.it, Tonazzi, Annamaria¹ (AUTHOR) c.indiveri@ibiom.cnr.it, Pierri, Ciro Leonardo² (AUTHOR) n.giangregorio@ibiom.cnr.it, Indiveri, Cesare^1,3 (AUTHOR)

Publikováno v: Biomolecules (2218-273X). Sep2024, Vol. 14 Issue 9, p1158. 26p.