Chemoenzymatic indican for light-driven denim dyeing

Autor: Gonzalo Nahuel Bidart, David Teze, Charlotte Uldahl Jansen, Eleonora Pasutto, Natalia Putkaradze, Anna-Mamusu Sesay, Folmer Fredslund, Leila Lo Leggio, Olafur Ögmundarson, Sumesh Sukumara, Katrine Qvortrup, Ditte Hededam Welner

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)

Abstract Blue denim, a billion-dollar industry, is currently dyed with indigo in an unsustainable process requiring harsh reducing and alkaline chemicals. Forming indigo directly in the yarn through indican (indoxyl-β-glucoside) is a promising alter

Externí odkaz: https://doaj.org/article/d6c0a335cc824cc389dba6bbedc73dd5

Engineering the substrate binding site of the hyperthermostable archaeal endo-β-1,4-galactanase from Ignisphaera aggregans

Autor: Sebastian J. Muderspach, Folmer Fredslund, Verena Volf, Jens-Christian Navarro Poulsen, Thomas H. Blicher, Mads Hartvig Clausen, Kim Krighaar Rasmussen, Kristian B. R. M. Krogh, Kenneth Jensen, Leila Lo Leggio

Publikováno v: Biotechnology for Biofuels, Vol 14, Iss 1, Pp 1-16 (2021)

Abstract Background Endo-β-1,4-galactanases are glycoside hydrolases (GH) from the GH53 family belonging to the largest clan of GHs, clan GH-A. GHs are ubiquitous and involved in a myriad of biological functions as well as being widely used industri

Externí odkaz: https://doaj.org/article/1a7bd7f27616404d8c9ce8214bb41518

Structure‐guided engineering of key amino acids in UGT85B1 controlling substrate and stereo‐specificity in aromatic cyanogenic glucoside biosynthesis

Autor: Rita Del Giudice, Natalia Putkaradze, Bruna Marques dos Santos, Cecilie Cetti Hansen, Christoph Crocoll, Mohammed Saddik Motawia, Folmer Fredslund, Tomas Laursen, Ditte Hededam Welner

Publikováno v: Del Giudice, R, Putkaradze, N, dos Santos, B M, Hansen, C C, Crocoll, C, Motawia, M S, Fredslund, F, Laursen, T & Welner, D H 2022, ' Structure-guided engineering of key amino acids in UGT85B1 controlling substrate and stereo-specificity in aromatic cyanogenic glucoside biosynthesis ', Plant Journal, vol. 111, no. 6, pp. 1539-1549 . https://doi.org/10.1111/tpj.15904

Cyanogenic glucosides are important defense molecules in plants with useful biological activities in animals. Their last biosynthetic step consists of a glycosylation reaction that confers stability and increases structural diversity and is catalyzed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::897dc0dfe10ca6ba66cd58e48bedc4b9
https://doi.org/10.1111/tpj.15904

Family 1 Glycosyltransferase UGT706F8 from Zea mays Selectively Catalyzes the Synthesis of Silibinin 7-O-β-d-Glucoside

Autor: Gonzalo N. Bidart, Natalia Putkaradze, Folmer Fredslund, Christian Kjeldsen, Ander Garralda Ruiz, Jens Ø. Duus, David Teze, Ditte H. Welner

Publikováno v: ACS Sustainable Chemistry & Engineering. 10:5078-5083

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::69451d9566c4a1540865a31f79ccc702
https://doi.org/10.1021/acssuschemeng.1c07593

Discovery of fungal oligosaccharide-oxidising flavo-enzymes with previously unknown substrates, redox-activity profiles and interplay with LPMOs

Autor: Frédéric Biaso, Thu V. Vuong, Bruno Guigliarelli, Bastien Bissaro, Tine Sofie Nielsen, Folmer Fredslund, Jean-Guy Berrin, Mireille Haon, Sebastian Meier, Maher Abou Hachem, Emma R. Master, Sacha Grisel, Majid Haddad Momeni, Bernard Henrissat, Olanrewaju Raji, Ditte Hededam Welner, Vincent Lombard

Publikováno v: Nature Communications
Nature Communications, 2021, 12 (1), ⟨10.1038/s41467-021-22372-0⟩
Haddad Momeni, M, Fredslund, F, Bissaro, B, Raji, O, Vuong, T V, Meier, S, Nielsen, T S, Lombard, V, Guigliarelli, B, Biaso, F, Haon, M, Grisel, S, Henrissat, B P, Welner, D H, Master, E R, Berrin, J-G & Abou Hachem, M 2021, ' Discovery of fungal oligosaccharide-oxidising flavo-enzymes with previously unknown substrates, redox-activity profiles and interplay with LPMOs ', Nature Communications, vol. 12, 2132 . https://doi.org/10.1038/s41467-021-22372-0
'Nature Communications ', vol: 12, pages: 2132-1-2132-13 (2021)
Nature Communications, Nature Publishing Group, 2021, 12 (1), ⟨10.1038/s41467-021-22372-0⟩
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)

Oxidative plant cell-wall processing enzymes are of great importance in biology and biotechnology. Yet, our insight into the functional interplay amongst such oxidative enzymes remains limited. Here, a phylogenetic analysis of the auxiliary activity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::836f8a3da28b588e84c0a3ec55df4040
https://aaltodoc.aalto.fi/handle/123456789/107194