Heat-treated human platelet pellet lysate modulates microglia activation, favors wound healing and promotes neuronal differentiation in vitro

Autor: Ouada Nebie, Lassina Barro, Yu-Wen Wu, Folke Knutson, Luc Buée, David Devos, Chih-Wei Peng, David Blum, Thierry Burnouf

Publikováno v: Platelets, Vol 32, Iss 2, Pp 226-237 (2021)

The neurorestorative efficacy of human platelet lysates in neurodegenerative disorders is still under investigation. Platelets prepared from standard and pathogen reduced platelet concentrates were pelletized, washed, concentrated, and subjected to f

Externí odkaz: https://doaj.org/article/580a1a8715cf47dc92c176745788b6f4

The EHA Research Roadmap: Transfusion Medicine

Autor: Simon J. Stanworth, Anneke Brand, Srini V. Kaveri, Hans Vrielink, Andreas Greinacher, Dragoslav Domanović, Marieke von Lindern, Shubha Allard, Jagadeesh Bayry, Milos Bohonek, Andreas Buser, Frans H. J. Claas, Folke Knutson, Miguel Lozano, Martin L. Olsson, France Pirenne, Paolo Rebulla, Cynthia So-Osman, Jean-Daniel Tissot, Ashley M. Toye, Ines Ushiro-Lumb, Emile van den Akker, Sacha Zeerleder

Publikováno v: HemaSphere, Vol 6, Iss 2, p e670 (2022)

Externí odkaz: https://doaj.org/article/bdb65d7605124f069e1906594c4f9e76

Polyvinylalcohol-carbazate (PVAC) reduces red blood cell hemolysis.

Autor: Felix Sellberg, Fanny Fredriksson, Thomas Engstrand, Tim Melander Bowden, Bo Nilsson, Jaan Hong, Folke Knutson, David Berglund

Publikováno v: PLoS ONE, Vol 14, Iss 12, p e0225777 (2019)

BACKGROUND AND OBJECTIVES:The objective of this study was to investigate whether a soluble polymer and aldehyde-scavenger, polyvinylalcohol-carbazate (PVAC), can inhibit hemolysis in the storage of red blood cells (RBC). STUDY DESIGN AND METHODS:The

Externí odkaz: https://doaj.org/article/10d6688340454da38bc2800fd2641a54

Removal of minute virus of mice-mock virus particles by nanofiltration of culture growth medium supplemented with 10% human platelet lysate

Autor: Lassina Barro, Naoto Watanabe, Thierry Burnouf, Folke Knutson, Liling Delila, Yu Wen Wu, Masayasu Takahara, Ouada Nebie

Publikováno v: Cytotherapy. 23:902-907

Background aims Platelet concentrates (PCs) are pooled to prepare human platelet lysate (HPL) supplements of growth media to expand primary human cells for transplantation; this increases the risk of contamination by known, emerging, and unknown viru

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de6a0a6274f9c4a3113b818e9f355aeb
https://doi.org/10.1016/j.jcyt.2021.05.006

The neuroprotective activity of heat-treated human platelet lysate biomaterials manufactured from outdated pathogen-reduced (amotosalen/UVA) platelet concentrates

Autor: Lassina Barro, Valérie Vingtdeux, Ouada Nebie, David Blum, Jean Christophe Devedjian, Ming Li Chou, Folke Knutson, Thierry Burnouf, Régis Bordet, Luc Buée, Aurélie Jonneaux, David Devos

Publikováno v: Journal of Biomedical Science, Vol 26, Iss 1, Pp 1-14 (2019)
Journal of Biomedical Science
Journal of Biomedical Science, BioMed Central, 2019, 26 (1), pp.89. ⟨10.1186/s12929-019-0579-9⟩
Journal of Biomedical Science, 2019, 26 (1), pp.89. ⟨10.1186/s12929-019-0579-9⟩

Background Effective neurorestorative therapies of neurodegenerative diseases must be developed. There is increasing interest in using human platelet lysates, rich in neurotrophic factors, as novel disease-modifying strategy of neurodegeneration. To

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38bff42e9111b7fe9aa0d630ec7c1416
http://link.springer.com/article/10.1186/s12929-019-0579-9