Publisher Correction:Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

Autor: Surendran, P, Feofanova, EV, Lahrouchi, N, Ntalla, I, Karthikeyan, S, Cook, J, Chen, L, Mifsud, B, Yao, C, Kraja, AT, Cartwright, JH, Hellwege, JN, Giri, A, Tragante, V, Thorleifsson, G, Liu, DJ, Prins, BP, Stewart, ID, Cabrera, CP, Eales, JM, Akbarov, A, Auer, PL, Bielak, LF, Bis, JC, Braithwaite, VS, Brody, JA, Daw, EW, Warren, HR, Drenos, F, Nielsen, SF, Faul, JD, Fauman, EB, Fava, C, Ferreira, T, Foley, CN, Franceschini, N, Gao, H, Giannakopoulou, O, Giulianini, F, Gudbjartsson, DF, Guo, X, Harris, SE, Havulinna, AS, Helgadottir, A, Huffman, JE, Hwang, S-J, Kanoni, S, Kontto, J, Larson, MG, Li-Gao, R, Lindstrom, J, Lotta, LA, Lu, Y, Luan, J, Mahajan, A, Malerba, G, Masca, NGD, Mei, H, Menni, C, Mook-Kanamori, DO, Mosen-Ansorena, D, Muller-Nurasyid, M, Pare, G, Paul, DS, Perola, M, Poveda, A, Rauramaa, R, Richard, M, Richardson, TG, Sepulveda, N, Sim, X, Smith, AV, Smith, JA, Staley, JR, Stanakova, A, Sulem, P, Theriault, S, Thorsteinsdottir, U, Trompet, S, Varga, TV, Velez Edwards, DR, Veronesi, G, Weiss, S, Willems, SM, Yao, J, Young, R, Yu, B, Zhang, W, Zhao, J-H, Zhao, W, Evangelou, E, Aeschbacher, S, Asllanaj, E, Blankenberg, S, Bonnycastle, LL, Bork-Jensen, J, Brandslund, I, Braund, PS, Burgess, S, Cho, K, Christensen, C, Connell, J, De Mutsert, R, Dominiczak, AF, Dorr, M, Eiriksdottir, G, Farmaki, A-E, Gaziano, JM, Grarup, N, Grove, ML, Hallmans, G, Hansen, T, Have, CT, Heiss, G, Jorgensen, ME, Jousilahti, P, Kajantie, E, Kamat, M, Karajamaki, A, Karpe, F, Koistinen, HA, Kovesdy, CP, Kuulasmaa, K, Laatikainen, I, Lannfelt, L, Lee, I-T, Lee, W-J, Linneberg, A, Martin, LW, Moitry, M, Nadkarni, G, Neville, MJ, Palmer, CNA, Papanicolaou, GJ, Pedersen, O, Peters, J, Poulter, N, Rasheed, A, Rasmussen, KL, Rayner, NW, Magi, R, Renstrom, F, Rettig, R, Rossouw, J, Schreiner, PJ, Sever, PS, Sigurdsson, EL, Skaaby, T, Sun, YV, Sundstrom, J, Thorgeirsson, G, Esko, T, Trabetti, E, Tsao, PS, Tuomi, T, Turner, ST, Tzoulaki, I, Vaartjes, I, Vergnaud, A-C, Willer, CJ, Wilson, PWF, Witte, DR, Yonova-Doing, E, Zhang, H, Aliya, N, Almgren, P, Amouyel, P, Asselbergs, FW, Barnes, MR, Blakemore, AI, Boehnke, M, Bots, ML, Bottinger, EP, Buring, JE, Chambers, JC, Chen, Y-DI, Chowdhury, R, Conen, D, Correa, A, Davey Smith, G, Boer, RAD, Deary, IJ, Dedoussis, G, Deloukas, P, Di Angelantonio, E, Elliott, P, Felix, SB, Ferrieres, J, Ford, I, Fornage, M, Franks, PW, Franks, S, Frossard, P, Gambaro, G, Gaunt, TR, Groop, L, Gudnason, V, Harris, TB, Hayward, C, Hennig, BJ, Herzig, K-H, Ingelsson, E, Tuomilehto, J, Jarvelin, M-R, Jukema, JW, Kardia, SLR, Kee, F, Kooner, JS, Kooperberg, C, Launer, LJ, Lind, L, Loos, RJF, Majumder, AAS, Laakso, M, McCarthy, MI, Melander, O, Mohlke, KL, Murray, AD, Nordestgaard, BG, Orho-Melander, M, Packard, CJ, Padmanabhan, S, Palmas, W, Polasek, O, Porteous, DJ, Prentice, AM, Province, MA, Relton, CL, Rice, K, Ridker, PM, Rolandsson, O, Rosendaal, FR, Rotter, JI, Rudan, I, Salomaa, V, Samani, NJ, Sattar, N, Sheu, WH-H, Smith, BH, Soranzo, N, Spector, TD, Starr, JM, Sebert, S, Taylor, KD, Lakka, TA, Timpson, NJ, Tobin, MD, Van der Harst, P, Van der Meer, P, Ramachandran, VS, Verweij, N, Virtamo, J, Volker, U, Weir, DR, Zeggini, E, Charchar, FJ, Wareham, NJ, Langenberg, C, Tomaszewski, M, Butterworth, AS, Caulfield, MJ, Danesh, J, Edwards, TL, Holm, H, Hung, AM, Lindgren, CM, Liu, C, Manning, AK, Morris, AP, Morrison, AC, O'Donnell, CJ, Psaty, BM, Saleheen, D, Stefansson, K, Boerwinkle, E, Chasman, DI, Levy, D, Newton-Cheh, C, Munroe, PB, Howson, JMM

Publikováno v: Lifelines Cohort Study, EPIC-CVD, EPIC-InterAct, Understanding Society Scientific Group & Million Veteran Program 2021, ' Publisher Correction : Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals ', Nature Genetics, vol. 53, no. 5, 762 . https://doi.org/10.1038/s41588-021-00832-z

In the version of this article originally published, the e-mail address of corresponding author Patricia B. Munroe was incorrect. The error has been corrected in the HTML and PDF versions of the article.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca24b467be4299d8e41d6ecf1e8f4f28
https://portal.findresearcher.sdu.dk/da/publications/45d317bb-a79e-419e-a69b-f5b60c70fd68

Systematic discovery of gene-environment interactions underlying the human plasma proteome in UK Biobank.

Autor: Hillary RF; Optima Partners, Edinburgh, EH2 4HQ, UK.; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, EH4 2XU, UK.; Translational Sciences, Research and Development, Biogen Inc., Cambridge, MA, USA., Gadd DA; Optima Partners, Edinburgh, EH2 4HQ, UK.; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, EH4 2XU, UK.; Translational Sciences, Research and Development, Biogen Inc., Cambridge, MA, USA., Kuncheva Z; Optima Partners, Edinburgh, EH2 4HQ, UK.; Translational Sciences, Research and Development, Biogen Inc., Cambridge, MA, USA.; Bayes Centre, The University of Edinburgh, Edinburgh, EH8 9BT, UK., Mangelis T; Optima Partners, Edinburgh, EH2 4HQ, UK.; Translational Sciences, Research and Development, Biogen Inc., Cambridge, MA, USA.; Bayes Centre, The University of Edinburgh, Edinburgh, EH8 9BT, UK., Lin T; Translational Sciences, Research and Development, Biogen Inc., Cambridge, MA, USA., Ferber K; Translational Sciences, Research and Development, Biogen Inc., Cambridge, MA, USA., McLaughlin H; Translational Sciences, Research and Development, Biogen Inc., Cambridge, MA, USA., Runz H; Translational Sciences, Research and Development, Biogen Inc., Cambridge, MA, USA., Marioni RE; Optima Partners, Edinburgh, EH2 4HQ, UK. riccardo.marioni@ed.ac.uk.; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, EH4 2XU, UK. riccardo.marioni@ed.ac.uk.; Translational Sciences, Research and Development, Biogen Inc., Cambridge, MA, USA. riccardo.marioni@ed.ac.uk., Foley CN; Optima Partners, Edinburgh, EH2 4HQ, UK. chris.foley@optimapartners.co.uk.; Translational Sciences, Research and Development, Biogen Inc., Cambridge, MA, USA. chris.foley@optimapartners.co.uk.; Bayes Centre, The University of Edinburgh, Edinburgh, EH8 9BT, UK. chris.foley@optimapartners.co.uk., Sun BB; Translational Sciences, Research and Development, Biogen Inc., Cambridge, MA, USA. bbsun92@outlook.com.; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK. bbsun92@outlook.com.

Publikováno v: Nature communications [Nat Commun] 2024 Aug 26; Vol. 15 (1), pp. 7346. Date of Electronic Publication: 2024 Aug 26.

Author Correction: FinnGen provides genetic insights from a well-phenotyped isolated population.

Autor: Kurki MI; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA., Karjalainen J; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA., Palta P; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland.; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Sipilä TP; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland., Kristiansson K; Finnish Institute for Health and Welfare (THL), Helsinki, Finland., Donner KM; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland., Reeve MP; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland., Laivuori H; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland.; Medical and Clinical Genetics, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Department of Obstetrics and Gynecology, Tampere University Hospital, Tampere, Finland.; Faculty of Medicine and Health Technology, Center for Child, Adolescent and Maternal Health, University of Tampere, Tampere, Finland., Aavikko M; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland., Kaunisto MA; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland., Loukola A; Helsinki Biobank, University of Helsinki and Hospital District of Helsinki and Uusimaa, Helsinki, Finland., Lahtela E; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland., Mattsson H; Finnish Institute for Health and Welfare (THL), Helsinki, Finland., Laiho P; Finnish Institute for Health and Welfare (THL), Helsinki, Finland., Della Briotta Parolo P; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland., Lehisto AA; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland., Kanai M; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA., Mars N; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland., Rämö J; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland., Kiiskinen T; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland., Heyne HO; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Digital Health Center, Hasso Plattner Institute for Digital Engineering, University of Potsdam Potsdam, Potsdam, Germany.; Hasso Plattner Institute for Digital Health at Mount Sinai, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Veerapen K; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA., Rüeger S; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland., Lemmelä S; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland.; Finnish Institute for Health and Welfare (THL), Helsinki, Finland., Zhou W; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA., Ruotsalainen S; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland., Pärn K; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland., Hiekkalinna T; Finnish Institute for Health and Welfare (THL), Helsinki, Finland., Koskelainen S; Finnish Institute for Health and Welfare (THL), Helsinki, Finland., Paajanen T; Finnish Institute for Health and Welfare (THL), Helsinki, Finland., Llorens V; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland., Gracia-Tabuenca J; TAUCHI Research Center, Faculty of Information Technology and Communication Sciences, Tampere University, Tampere, Finland., Siirtola H; TAUCHI Research Center, Faculty of Information Technology and Communication Sciences, Tampere University, Tampere, Finland., Reis K; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Elnahas AG; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Sun B; Translational Biology, Research and Development, Biogen, Cambridge, MA, USA.; BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Foley CN; Optima Partners, Edinburgh, UK.; MRC Biostatistics Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK., Aalto-Setälä K; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Alasoo K; Institute of Computer Science, University of Tartu, Tartu, Estonia., Arvas M; Finnish Red Cross Blood Service, Helsinki, Finland., Auro K; GlaxoSmithKline, Espoo, Finland., Biswas S; Bristol Myers Squibb, New York, NY, USA., Bizaki-Vallaskangas A; Tampere University Hospital and Tampere University, Tampere, Finland., Carpen O; Helsinki Biobank, University of Helsinki and Hospital District of Helsinki and Uusimaa, Helsinki, Finland., Chen CY; Biogen, Cambridge, MA, USA., Dada OA; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland., Ding Z; Boehringer Ingelheim, Ingelheim am Rhein, Germany., Ehm MG; GlaxoSmithKline, Collegeville, PA, USA., Eklund K; Division of Rheumatology, Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland.; Orton Orthopedic Hospital, Helsinki, Finland., Färkkilä M; Abdominal Center, Helsinki University Hospital, Helsinki University, Helsinki, Finland., Finucane H; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA., Ganna A; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA., Ghazal A; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland., Graham RR; Maze Therapeutics, South San Francisco, CA, USA., Green EM; Maze Therapeutics, South San Francisco, CA, USA., Hakanen A; Auria Biobank, University of Turku and Turku University Hospital, Turku, Finland., Hautalahti M; FINBB, Finnish Biobank Cooperative, Helsinki, Finland., Hedman ÅK; Pfizer, New York, NY, USA.; Department of Medicine, Karolinska Institute, Solna, Sweden., Hiltunen M; Clinical Biobank Tampere, Tampere University and Tampere University Hospital, Tampere, Finland., Hinttala R; Medical Research Center Oulu and PEDEGO Research Unit, University of Oulu, Oulu, Finland.; Biocenter Oulu, University of Oulu, Oulu, Finland.; Oulu University Hospital, Oulu, Finland., Hovatta I; Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; SleepWell Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Hu X; Pfizer, New York, NY, USA., Huertas-Vazquez A; Merck & Co, Kenilworth, NJ, USA., Huilaja L; PEDEGO Research Unit, University of Oulu, Oulu, Finland.; Department of Dermatology and Medical Research Center Oulu, Oulu University Hospital, Oulu, Finland., Hunkapiller J; Genentech, San Francisco, CA, USA., Jacob H; AbbVie, Chicago, IL, USA., Jensen JN; Boehringer Ingelheim, Ingelheim am Rhein, Germany., Joensuu H; Helsinki University Hospital and University of Helsinki, Helsinki, Finland., John S; Biogen, Cambridge, MA, USA., Julkunen V; Neuro Center, Neurology, Kuopio University Hospital, Kuopio, Finland.; Institute of Clinical Medicine-Neurology, University of Eastern Finland, Kuopio, Finland., Jung M; Boehringer Ingelheim, Ingelheim am Rhein, Germany., Junttila J; Northern Finland Biobank Borealis, University of Oulu, Northern Ostrobothnia Hospital District, Oulu, Finland., Kaarniranta K; Department of Ophthalmology, Kuopio University Hospital, Kuopio, Finland.; Department of Ophthalmology, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland., Kähönen M; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland., Kajanne R; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland., Kallio L; Auria Biobank, University of Turku and Turku University Hospital, Turku, Finland., Kälviäinen R; Epilepsy Center, Kuopio University Hospital, Kuopio, Finland.; Department of Neurology, University of Eastern Finland, Kuopio, Finland., Kaprio J; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland.; Department of Public Health, University of Helsinki, Helsinki, Finland., Kerimov N; Institute of Computer Science, University of Tartu, Tartu, Estonia., Kettunen J; Finnish Institute for Health and Welfare (THL), Helsinki, Finland.; Biocenter Oulu, University of Oulu, Oulu, Finland.; Computational Medicine, Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland., Kilpeläinen E; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland., Kilpi T; Finnish Institute for Health and Welfare (THL), Helsinki, Finland., Klinger K; Translational Sciences, Sanofi R&D, Framingham, MA, USA., Kosma VM; Biobank of Eastern Finland, University of Eastern Finland, Kuopio, Finland.; Kuopio University Hospital, Kuopio, Finland., Kuopio T; Central Finland Biobank, Central Finland Health Care District, Jyväskylä, Finland., Kurra V; Department of Clinical Genetics, Tampere University Hospital, Tampere, Finland.; Department of Clinical Genetics, Faculty of Medicine and Health Technology, Tampere, Finland., Laisk T; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Laukkanen J; Central Finland Biobank, Central Finland Health Care District, Jyväskylä, Finland.; Department of Medicine, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland., Lawless N; Boehringer Ingelheim, Ingelheim am Rhein, Germany., Liu A; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland., Longerich S; Merck & Co, Kenilworth, NJ, USA., Mägi R; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Mäkelä J; FINBB, Finnish Biobank Cooperative, Turku, Finland., Mäkitie A; Department of Otorhinolaryngology-Head and Neck Surgery, University of Helsinki, Helsinki, Finland.; Helsinki University Hospital, Helsinki, Finland., Malarstig A; Pfizer, Cambridge, MA, USA.; Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Solna, Sweden., Mannermaa A; Biobank of Eastern Finland, University of Eastern Finland, Kuopio, Finland.; Kuopio University Hospital, Kuopio, Finland., Maranville J; Bristol Myers Squibb, New York, NY, USA., Matakidou A; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Meretoja T; Helsinki University Hospital and University of Helsinki, Helsinki, Finland., Mozaffari SV; Maze Therapeutics, South San Francisco, CA, USA., Niemi MEK; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland., Niemi M; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; TAUCHI Research Center & Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Niiranen T; Finnish Institute for Health and Welfare (THL), Helsinki, Finland.; Turku University Hospital and University of Turku, Turku, Finland., O Donnell CJ; Novartis Institutes for BioMedical Research, Cambridge, MA, USA., Obeidat ME; Novartis Institutes for BioMedical Research, Cambridge, MA, USA., Okafo G; Boehringer Ingelheim, Ingelheim am Rhein, Germany., Ollila HM; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland.; Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Boston, MA, USA., Palomäki A; Turku University Hospital and University of Turku, Turku, Finland., Palotie T; Department of Oral and Maxillofacial Diseases, Helsinki University Hospital, Helsinki, Finland.; Department of Oral and Maxillofacial Diseases, University of Helsinki, Helsinki, Finland., Partanen J; Finnish Red Cross Blood Service, Helsinki, Finland.; Finnish Hematological Biobank, Helsinki, Finland., Paul DS; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Pelkonen M; Department of Pulmonary Diseases, Kuopio University Hospital, Kuopio, Finland., Pendergrass RK; Genentech, San Francisco, CA, USA., Petrovski S; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Pitkäranta A; Department of Otorhinolaryngology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland., Platt A; Translational Science and Experimental Medicine, Research and Early Development, Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Pulford D; GlaxoSmithKline, Stevenage, UK., Punkka E; Helsinki Biobank, University of Helsinki and Hospital District of Helsinki and Uusimaa, Helsinki, Finland., Pussinen P; Department of Oral and Maxillofacial Diseases, University of Helsinki, Helsinki, Finland., Raghavan N; Merck & Co, Kenilworth, NJ, USA., Rahimov F; AbbVie, Chicago, IL, USA., Rajpal D; Translational Sciences, Sanofi R&D, Framingham, MA, USA., Renaud NA; Novartis Institutes for BioMedical Research, Cambridge, MA, USA., Riley-Gillis B; AbbVie, Chicago, IL, USA., Rodosthenous R; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland., Saarentaus E; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland., Salminen A; Department of Oral and Maxillofacial Diseases, University of Helsinki, Helsinki, Finland., Salminen E; Helsinki University Hospital, Helsinki, Finland.; Department of Clinical Genetics, HUSLAB, HUS Diagnostic Center, University of Helsinki, Helsinki, Finland., Salomaa V; Finnish Institute for Health and Welfare (THL), Helsinki, Finland., Schleutker J; Auria Biobank, University of Turku and Turku University Hospital, Turku, Finland., Serpi R; Northern Finland Biobank Borealis, University of Oulu, Northern Ostrobothnia Hospital District, Oulu, Finland., Shen HY; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland., Siegel R; Novartis Institutes for BioMedical Research, Basel, Switzerland., Silander K; Finnish Institute for Health and Welfare (THL), Helsinki, Finland., Siltanen S; Finnish Clinical Biobank Tampere, Tampere University and Tampere University Hospital, Tampere, Finland., Soini S; Finnish Institute for Health and Welfare (THL), Helsinki, Finland., Soininen H; Department of Neurology, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland., Sul JH; Merck & Co, Kenilworth, NJ, USA., Tachmazidou I; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Tasanen K; PEDEGO Research Unit, University of Oulu, Oulu, Finland.; Department of Dermatology and Medical Research Center Oulu, Oulu University Hospital, Oulu, Finland., Tienari P; Department of Neurology, Helsinki University Hospital, Helsinki, Finland.; Translational Immunology, Research Programs Unit, University of Helsinki, Helsinki, Finland., Toppila-Salmi S; Department of Allergy, Helsinki University Hospital and University of Helsinki, Helsinki, Finland., Tukiainen T; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland., Tuomi T; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland.; Abdominal Center, Endocrinology, Helsinki University Hospital, Helsinki, Finland.; Folkhalsan Research Center, Helsinki, Finland.; Research Program of Clinical and Molecular Metabolism, University of Helsinki, Helsinki, Finland., Turunen JA; Helsinki University Hospital and University of Helsinki, Helsinki, Finland.; Eye Genetics Group, Folkhälsan Research Center, Helsinki, Finland., Ulirsch JC; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA, USA., Vaura F; Finnish Institute for Health and Welfare (THL), Helsinki, Finland.; University of Turku, Turku, Finland., Virolainen P; Auria Biobank, University of Turku and Turku University Hospital, Turku, Finland., Waring J; AbbVie, Chicago, IL, USA., Waterworth D; Janssen Research & Development, Spring House, PA, USA., Yang R; Janssen Biotech, Beerse, Belgium., Nelis M; Genomics Core Facility, Institute of Genomics, University of Tartu, Tartu, Estonia., Reigo A; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Metspalu A; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Milani L; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Esko T; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Fox C; Merck & Co, Kenilworth, NJ, USA., Havulinna AS; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland.; Finnish Institute for Health and Welfare (THL), Helsinki, Finland., Perola M; Finnish Institute for Health and Welfare (THL), Helsinki, Finland., Ripatti S; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland., Jalanko A; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland., Laitinen T; Finnish Clinical Biobank Tampere, Tampere University and Tampere University Hospital, Tampere, Finland., Mäkelä TP; Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland., Plenge R; Bristol Myers Squibb, New York, NY, USA., McCarthy M; Genentech, San Francisco, CA, USA., Runz H; Biogen, Cambridge, MA, USA., Daly MJ; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA., Palotie A; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland. aarno.palotie@helsinki.fi.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA. aarno.palotie@helsinki.fi.; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA, USA. aarno.palotie@helsinki.fi.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA. aarno.palotie@helsinki.fi.

Publikováno v: Nature [Nature] 2023 Mar; Vol. 615 (7952), pp. E19.

Genetic map of regional sulcal morphology in the human brain from UK biobank data.

Autor: Sun BB; Translational Biology, Research & Development, Biogen Inc., Cambridge, MA, US. bbsun92@outlook.com.; BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. bbsun92@outlook.com., Loomis SJ; Translational Biology, Research & Development, Biogen Inc., Cambridge, MA, US., Pizzagalli F; Department of Neuroscience 'Rita Levi Montalcini', University of Turin, Turin, Italy.; Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA, US., Shatokhina N; Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA, US., Painter JN; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Foley CN; MRC Biostatistics Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK.; Optima Partners, Edinburgh, UK., Jensen ME; Clinical Sciences, Research & Development, Biogen Inc., Cambridge, MA, US., McLaren DG; Clinical Sciences, Research & Development, Biogen Inc., Cambridge, MA, US., Chintapalli SS; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, US., Zhu AH; Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA, US., Dixon D; Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA, US., Islam T; Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA, US., Ba Gari I; Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA, US., Runz H; Translational Biology, Research & Development, Biogen Inc., Cambridge, MA, US., Medland SE; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Thompson PM; Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA, US. pthomp@usc.edu., Jahanshad N; Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA, US. njahansh@usc.edu., Whelan CD; Translational Biology, Research & Development, Biogen Inc., Cambridge, MA, US. christopherdwhelan@outlook.com.

Publikováno v: Nature communications [Nat Commun] 2022 Oct 14; Vol. 13 (1), pp. 6071. Date of Electronic Publication: 2022 Oct 14.

Genetically Predicted Glucose-Dependent Insulinotropic Polypeptide (GIP) Levels and Cardiovascular Disease Risk Are Driven by Distinct Causal Variants in the GIPR Region.

Autor: Bowker N; MRC Epidemiology Unit, University of Cambridge, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, U.K., Hansford R; MRC Epidemiology Unit, University of Cambridge, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, U.K., Burgess S; MRC Biostatistics Unit, Cambridge Institute of Public Health, Cambridge, U.K.; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, U.K., Foley CN; MRC Biostatistics Unit, Cambridge Institute of Public Health, Cambridge, U.K.; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, U.K., Auyeung VPW; MRC Epidemiology Unit, University of Cambridge, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, U.K., Erzurumluoglu AM; MRC Epidemiology Unit, University of Cambridge, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, U.K., Stewart ID; MRC Epidemiology Unit, University of Cambridge, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, U.K., Wheeler E; MRC Epidemiology Unit, University of Cambridge, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, U.K., Pietzner M; MRC Epidemiology Unit, University of Cambridge, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, U.K., Gribble F; University of Cambridge, Wellcome Trust/MRC Institute of Metabolic Science, and MRC Metabolic Diseases Unit, Addenbrooke's Hospital, Cambridge, U.K., Reimann F; University of Cambridge, Wellcome Trust/MRC Institute of Metabolic Science, and MRC Metabolic Diseases Unit, Addenbrooke's Hospital, Cambridge, U.K., Bhatnagar P; Diabetes and Complications Therapy Area, Eli Lilly & Company, Indianapolis, IN., Coghlan MP; Diabetes and Complications Therapy Area, Eli Lilly & Company, Indianapolis, IN., Wareham NJ; MRC Epidemiology Unit, University of Cambridge, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, U.K., Langenberg C; MRC Epidemiology Unit, University of Cambridge, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, U.K. claudia.langenberg@mrc-epid.cam.ac.uk.; Computational Medicine, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany.

Publikováno v: Diabetes [Diabetes] 2021 Nov; Vol. 70 (11), pp. 2706-2719. Date of Electronic Publication: 2021 Aug 23.