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Autor:
Kate T. Murphy, Kristy Swiderski, James G. Ryall, Jonathan R. Davey, Hongwei Qian, Séverine Lamon, Victoria C. Foletta, Jennifer Trieu, Annabel Chee, Suzannah J. Read, Timur Naim, Paul Gregorevic, Gordon S. Lynch
Publikováno v:
JCSM Rapid Communications, Vol 5, Iss 1, Pp 102-116 (2022)
Abstract Background Cachexia is a debilitating complication of cancer characterized by progressive wasting and weakness of skeletal muscles that reduces quality of life and can compromise survival. Many anticancer treatments, such as chemotherapy, al
Externí odkaz:
https://doaj.org/article/4b80acbe02104dee8ebddccaedd7c9ba
Autor:
Emma J. Solly, Meaghan Clough, Allison M. McKendrick, Paige Foletta, Owen B. White, Joanne Fielding
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Visual snow syndrome (VSS) is a poorly understood neurological disorder that features a range of disabling sensory changes. Visual processing changes revealed previously in VSS appear consistent with poor attentional control, specifically, w
Externí odkaz:
https://doaj.org/article/0c7c8756bebb485d9c8be66d3e4f5f74
Autor:
Stavroula Tsitkanou, Paul A. Della Gatta, Gavin Abbott, Marita A. Wallace, Angus Lindsay, Frederico Gerlinger-Romero, Adam K. Walker, Victoria C. Foletta, Aaron P. Russell
Publikováno v:
Neurobiology of Disease, Vol 162, Iss , Pp 105559- (2022)
Skeletal muscle dysfunction may contribute to the progression and severity of amyotrophic lateral sclerosis (ALS). In the present study, we characterized the skeletal muscle pathophysiology in an inducible transgenic mouse model (rNLS8) that develops
Externí odkaz:
https://doaj.org/article/9a0c4acf9c344503aa2f38b7f930adf4
Autor:
Paige J. Foletta, Meaghan Clough, Allison M. McKendrick, Emma J. Solly, Owen B. White, Joanne Fielding
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Visual snow syndrome (VSS) is a complex, sensory processing disorder. We have previously shown that visual processing changes manifest in significantly faster eye movements toward a suddenly appearing visual stimulus and difficulty inhibiting an eye
Externí odkaz:
https://doaj.org/article/710c66dbb2704f71b65c5a9a66712a9e
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Objective: To characterise the psychiatric symptoms of visual snow syndrome (VSS), and determine their relationship to quality of life and severity of visual symptoms.Methods: One hundred twenty-five patients with VSS completed a battery of questionn
Externí odkaz:
https://doaj.org/article/8657b7c6a27847eda9cbcd453895d0e4
Autor:
Ahrathy Selathurai, Greg M. Kowalski, Shaun A. Mason, Damien L. Callahan, Victoria C. Foletta, Paul A. Della Gatta, Angus Lindsay, Steven Hamley, Gunveen Kaur, Annie R. Curtis, Micah L. Burch, Teddy Ang, Sean L. McGee, Clinton R. Bruce
Publikováno v:
Molecular Metabolism, Vol 27, Iss , Pp 33-46 (2019)
Objective: Phosphatidylethanolamine (PtdEtn) is a major phospholipid in mammals. It is synthesized via two pathways, the CDP-ethanolamine pathway in the endoplasmic reticulum and the phosphatidylserine (PtdSer) decarboxylase (PSD) pathway in the mito
Externí odkaz:
https://doaj.org/article/014e06075bd9459593a0edd456e20e9c
Publikováno v:
BMC Molecular and Cell Biology, Vol 20, Iss 1, Pp 1-11 (2019)
Abstract Background MicroRNAs (miRNAs) are increasingly being identified as modulatory molecules for physiological and pathological processes in muscle. Here, we investigated whether miRNAs influenced the expression of the stress-responsive gene N-my
Externí odkaz:
https://doaj.org/article/a56e6e6ff54a491a9008c4b3f34cfa50
Publikováno v:
Frontiers in Neurology, Vol 10 (2019)
Amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease, involves the rapid deterioration of motor neurons resulting in severe muscle atrophy and respiratory insufficiency. It is considered a “multisystemic” disease with many poten
Externí odkaz:
https://doaj.org/article/038a324be37540dd817317d591829e7e
Autor:
Erin L. Brown, Victoria C. Foletta, Craig R. Wright, Patricio V. Sepulveda, Nicky Konstantopoulos, Andrew Sanigorski, Paul Della Gatta, David Cameron-Smith, Anastasia Kralli, Aaron P. Russell
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
The transcriptional coactivators peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) and PGC-1β are positive regulators of skeletal muscle mass and energy metabolism; however, whether they influence muscle growth and metabolic ad
Externí odkaz:
https://doaj.org/article/d3b201bbedd745bf8ccf4940a20531a6