Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Foldamères"'
Autor:
Hacihasanoglu, Antoine
Organocatalysis is a rapidly expanding methodology enabling challenging chemical transformations to be performed in the broad context of sustainable chemistry (metal-free procedures, catalyst recycling…). Potential applications include the rapid el
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______166::836efc5e319da59cf638b59dc26d5c66
https://theses.hal.science/tel-03917153
https://theses.hal.science/tel-03917153
Autor:
Laxio Arenas, José
In recent decades, foldamers have emerged as a promising tool for developing bioactive molecules that mimic the secondary structures of proteins. These foldamers are mainly used to modulate protein-protein interactions involved in many diseases, incl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_____10369::ee2ad502f156bc8d30d8b930c692d5ec
https://theses.hal.science/tel-03962087
https://theses.hal.science/tel-03962087
Autor:
BOULLOY, Alice
Publikováno v:
Organic chemistry. Université de Bordeaux, 2021. English. ⟨NNT : 2021BORD0193⟩
The field of saccharide recognition using abiotic receptors has grown over the years. Among the many different structures designed, a class of receptors, foldamers, able to fold into a well-defined structure, has shown great promise in selective bind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::18a68677c626a3b3cea25382f27caeab
https://tel.archives-ouvertes.fr/tel-03351538/document
https://tel.archives-ouvertes.fr/tel-03351538/document
Autor:
Messerschmitt, Alexandre
L’utilisation d’oligomères d’α-amino-γ-lactame (Agl-αAA) comme vecteurs de pénétration intracellulaire est décrite dans ce manuscrit. Nous avons montré que ces oligomères structurés en ruban sont capables de traverser la membrane plas
Externí odkaz:
http://www.theses.fr/2019MONTS018/document
Autor:
Messerschmitt, Alexandre
Publikováno v:
Autre. Université Montpellier, 2019. Français. ⟨NNT : 2019MONTS018⟩
The use of α-amino-γ-lactam oligomers (Agl-αAA) as cell penetrating vectors are described in this work. These ribbon structured oligomers are able to cross the cell membrane to reach the cytosol and deliver a biologically active cargo. Unlike pept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::e6d370bf2dea77d1e242d686e015a054
https://theses.hal.science/tel-02297838
https://theses.hal.science/tel-02297838
Autor:
Rzeigui, Maha
Publikováno v:
Chimie organique. Université Clermont Auvergne [2017-2020]; Université de Carthage (Tunisie), 2020. Français. ⟨NNT : 2020CLFAC025⟩
Peptoids (N-substituted glycine oligomers) are an important class of foldamers capable of adopting a range of unique secondary structures based on the cis/trans conformation of their constituting main chain tertiary amide bonds. The folding mode of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2e966ec9168723ce8bdc45412828c4d5
https://theses.hal.science/tel-03738073/document
https://theses.hal.science/tel-03738073/document
Autor:
Perdriau, Camille
Publikováno v:
Chimie organique. Université de Bordeaux, 2019. Français. ⟨NNT : 2019BORD0308⟩
Recent advances in molecular biology gave rise to the emergence of biologics (antibodies, hormones) as therapeutic agents. Peptides which are able to adopt secondary structures encountered in proteins and presenting intermediates features between sma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::04cd94d2b0e20c3403ad9bafa77269b5
https://tel.archives-ouvertes.fr/tel-03515987
https://tel.archives-ouvertes.fr/tel-03515987
Autor:
Bornerie, Megane
Publikováno v:
Chimie organique. Université de Bordeaux, 2019. Français. ⟨NNT : 2019BORD0210⟩
Peptidomimetic oligourea foldamers are now used to mimic the composition and the structure of cell-penetrating peptides (CPPs) to deliver biomolecules (i.e nucleic acids) into cells. It has been recently shown that dimerisation of short amphipatic ol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::8f9255e503e8ea80285ba2c7812d707a
https://tel.archives-ouvertes.fr/tel-03331631
https://tel.archives-ouvertes.fr/tel-03331631
Autor:
Aguesseau, Julie
Les travaux décrits dans ce manuscrit concernent la synthèse d’oligomères de γ-amino acides hétérocycliques contraints, appelés ATCs (acides 4-Amino-(méthyl)-1,3-Thiazole-5-Carboxyliques), leur application en catalyse énamine et leur étud
Externí odkaz:
http://www.theses.fr/2019MONTS043/document
Autor:
Wang, Jinhua
Les foldamères d’oligoquinoline carboxamide forment des structures hélicoïdales en solution et dans le solide. Ces structures sont stabilisées par liaisons hydrogène, empilement aromatique et interactions électrostatiques. Dans une première
Externí odkaz:
http://www.theses.fr/2019BORD0122/document