Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Folayemi Olayinka-Adefemi"'
Autor:
Nnamdi Ikeogu, Folayemi Olayinka-Adefemi, Chidalu Edechi, Chukwunonso Onyilagha, Ping Jia, Aaron Marshall, Julius Ode, Jude Uzonna
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
African trypanosomiasis, a neglected tropical disease, is caused by diverse species of the protozoan parasite belonging to the genus Trypanosoma. Although anti-trypanosomal medications exist, the increase in drug resistance and persistent antigenic v
Externí odkaz:
https://doaj.org/article/700a88ce6d5542ccaca497752f68f436
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Phosphoinositide 3-kinase delta (PI3Kδ) plays key roles in normal B cell activation and is chronically activated in malignant B cells. Targeting of PI3Kδ using FDA-approved drugs Idelalisib or Umbralisib has shown efficacy in treatment of multiple
Externí odkaz:
https://doaj.org/article/3b37015d9e6b4e7fab38378cc6ddab3c
Autor:
Shiby Kuriakose, Chukwunonso Onyilagha, Rani Singh, Folayemi Olayinka-Adefemi, Ping Jia, Jude E. Uzonna
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
It is known that Trypanosoma congolense infection in mice is associated with increased production of proinflammatory cytokines by macrophages and monocytes. However, the intracellular signaling pathways leading to the production of these cytokines st
Externí odkaz:
https://doaj.org/article/2a1245ef430f43aa9f85bd7b443b6da8
Autor:
Jude E. Uzonna, Folayemi Olayinka-Adefemi, Sen Hou, Chukwunonso Onyilagha, Aaron J. Marshall, Nipun Jayachandran, Ping Jia
Publikováno v:
The Journal of Immunology. 207:1401-1410
PI3Kδ is critical in generating humoral and regulatory immune responses. In this study, we determined the impact of PI3Kδ in immunity to Trypanosoma congolense, an African trypanosome that can manipulate and evade Ab responses critical for protecti
Autor:
Laura K. Cole, Folayemi Olayinka-Adefemi, Ejlal Abu-El-Rub, Grant M. Hatch, Aaron J. Marshall, Hana M. Zegallai, Genevieve C. Sparagna
Publikováno v:
bioRxiv
Barth Syndrome (BTHS) is a rare X-linked genetic disorder caused by mutation in the TAFAZZIN gene which encodes the cardiolipin (CL) transacylase tafazzin (Taz). Taz deficiency in BTHS patients results in reduced CL in their tissues and a neutropenia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2df07ad181e54b43a12d624673d64427
https://doi.org/10.1101/2021.09.07.459330
https://doi.org/10.1101/2021.09.07.459330
Autor:
Folayemi, Olayinka-Adefemi, Chukwunonso, Onyilagha, Nipun, Jayachandran, Sen, Hou, Ping, Jia, Jude, Uzonna, Aaron J, Marshall
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 207(5)
PI3Kδ is critical in generating humoral and regulatory immune responses. In this study, we determined the impact of PI3Kδ in immunity to
Autor:
Folayemi Olayinka-Adefemi, Ping Jia, Jude E. Uzonna, Rani Singh, Shiby Kuriakose, Chukwunonso Onyilagha
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology, Vol 10 (2019)
Although it is known that Trypanosoma congolense infection in mice is associated with increased production of proinflammatory cytokines by macrophages and monocytes, the intracellular signaling pathways leading to the production of these cytokines re
Autor:
Folayemi Olayinka-Adefemi, Chukwunonso Onyilagha, Nipun Jayachandran, Sen Hou, Ping Jia, Jude E Uzonna, Aaron J Marshall
Publikováno v:
The Journal of Immunology. 204:82.39-82.39
The delta isoform of PI 3-kinase (PI3Kδ) has important functions in B cell activation. Trypanosoma parasites utilize several mechanisms to exploit and evade host B cell and antibody responses critical for immunity. We sought to determine the impact