Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Folake A. Egbewande"'
Publikováno v:
Marine Drugs, Vol 21, Iss 5, p 317 (2023)
The incorporation of bromine, iodine or fluorine into the tricyclic core structure of thiaplakortone A (1), a potent antimalarial marine natural product, is reported. Although yields were low, it was possible to synthesise a small nine-membered libra
Externí odkaz:
https://doaj.org/article/462bd368d90f4f7bb0725e71c68cfabb
Publikováno v:
Molecules, Vol 24, Iss 21, p 3938 (2019)
The reaction of papaverine with a series of Baran DiversinatesTM is reported. Although the yields were low, it was possible to synthesize a small biodiscovery library using this plant alkaloid as a scaffold for late-stage C−H functionalization. Ten
Externí odkaz:
https://doaj.org/article/2e5345c6703f47fd8f6bda7c3aaaf6a4
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 27:3185-3189
The plant natural product, valerenic acid (1) was chosen as a desirable scaffold for the generation of a novel screening library due to its drug-like physicochemical parameters (such as LogP, hydrogen bond donor/acceptor counts, and molecular weight)
Autor:
Rohan A. Davis, Claire Levrier, Martin C. Sadowski, Mark J. Coster, Folake A Egbewande, Jonathan M. White, Kaylyn D. Tousignant, Colleen C. Nelson
Publikováno v:
Journal of natural products. 81(4)
The naturally occurring pentacyclic diterpenoid gibberellic acid (1) was used in the generation of a drug-like amide library using parallel-solution-phase synthesis. Prior to the synthesis, a virtual library was generated and prioritized based on dru
Publikováno v:
European Journal of Inorganic Chemistry. 2014:1174-1184
Arene ruthenium complexes of α-amino acids, obtained by mixing aqueous solutions of [(η6-p-cymene)RuCl2]2 in the presence of AgCF3SO3 with various amino acids, have been studied at 37 °C using NMR spectroscopy and electrospray ionization mass spec