Zobrazeno 1 - 10
of 140
pro vyhledávání: '"Fokko J. Van Der Woude"'
Autor:
Verena Peters, Eva Riedl, Jacob van den Born, Benito A. Yard, Fokko J. van der Woude, Sibylle Sauerhoefer, Gerjan Navis, Paula Sternik, Paul Brinkkoetter, Bart Janssen, Robert H. Henning, Hannes Koeppel, Stephan J. L. Bakker, Frederick Pfister, Hanswalter Zentgraf
Publikováno v:
Diabetes
OBJECTIVE The (CTG)n polymorphism in the serum carnosinase (CN-1) gene affects CN-1 secretion. Since CN-1 is heavily glycosylated and glycosylation might influence protein secretion as well, we tested the role of N-glycosylation for CN-1 secretion an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6971aa42ddcada70b01bb19a60a4b615
http://europepmc.org/articles/PMC2911063
http://europepmc.org/articles/PMC2911063
Autor:
Marcus J. Moeller, Gang Yuan, Fokko J. van der Woude, Wilhelm Kriz, Jürgen Floege, Michael Neumaier, Norbert Gretz, Gerald S. Braun, Sibylle Sauerhöfer, Martina Deinzer
Publikováno v:
Diabetes. 56:2425-2432
OBJECTIVE—Carnosinase 1 (CN1) is a secreted dipeptidase that hydrolyzes l-carnosine. Recently, we have identified an allelic variant of human CN1 (hCN1) that results in increased enzyme activity and is associated with susceptibility for diabetic ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b7b755a76e55dcde58724df3fb13fc6
https://doi.org/10.2337/db07-0177
https://doi.org/10.2337/db07-0177
Autor:
Benito A. Yard, Uwe Gottmann, Zhenzi Liu, Peter Schnuelle, Claude Braun, Simone Hoeger, Rainer Birck, Fokko J. van der Woude
Publikováno v:
Transplant International. 20:790-799
Brain death (BD) is associated with profound inflammation in end-organs. Dopamine (DA) treatment reduces this inflammatory response, but the underlying mechanisms remain thus far largely unknown. In this study, we investigated if the anti-inflammator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12b1d3709a172977f3c44bed63f10e91
https://doi.org/10.1111/j.1432-2277.2007.00510.x
https://doi.org/10.1111/j.1432-2277.2007.00510.x
Autor:
Jan G. Zijlstra, Benito A. Yard, Klaus van Ackern, Neysan Rafat, Fokko J. van der Woude, Jutta Schulte, Joachim Brade, Paul T. Brinkkoetter, Grietje Beck, Christine Hanusch
Publikováno v:
Critical Care Medicine, 35(7), 1677-1684. LIPPINCOTT WILLIAMS & WILKINS
Objective: Endothelial damage and detachment of endothelial cells are known to occur in septic patients. Thus, recruitment of circulating enclothelial progenitor cells (cEPCs) to these lesions might have a beneficial effect on the clinical course in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca4b5afeda0ffbe19853ad491a283568
https://doi.org/10.1097/01.ccm.0000269034.86817.59
https://doi.org/10.1097/01.ccm.0000269034.86817.59
Autor:
Benito A. Yard, Volker Nickeleit, Astrid Mueller-Falcke, Fokko J. van der Woude, Peter Schnuelle, Uwe Gottmann, Claude Braun, Rainer Birck
Publikováno v:
Transplant International. 20:542-549
Summary The aim of the study was to evaluate the effect of the hypersulfated nonanticoagulant heparin derivative LU 51198 (LU) and of the low molecular weight heparin reviparin (REVI) on ischemia/reperfusion (I/R) injury, acute rejection (AR) and chr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7721e16d985c8f706343c88eb5286a45
https://doi.org/10.1111/j.1432-2277.2007.00471.x
https://doi.org/10.1111/j.1432-2277.2007.00471.x
Autor:
Bart Janssen, Pamela J. Hicks, Carl D. Langefeld, Michèle M. Sale, Fokko J. van der Woude, Stephen S. Rich, Caitrin W. McDonough, Barry I. Freedman, Donald W. Bowden, Eric D. Pierson, Jianzhao Xu, B. A. Yard
Publikováno v:
Nephrology Dialysis Transplantation. 22:1131-1135
Background. Four linkage analyses have identified a region on chromosome 18q22-23 that appears to harbour a diabetic nephropathy (DN) susceptibility locus. A trinucleotide repeat sequence in exon 2 of the carnosinase gene (CNDP1) residing on 18q22.3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a870ae9f1d99e8180b7702e8791f660
https://doi.org/10.1093/ndt/gfl717
https://doi.org/10.1093/ndt/gfl717
Publikováno v:
Transplant International. 19:947-959
Adequate volume maintenance is essential to prevent acute renal failure during major surgery or to ensure graft function after renal transplantation. The various recommendations on the optimum fluid therapy are based, at best, on sparse evidence only
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eda8a3f03b34edf66ef60b16699ff6f
https://doi.org/10.1111/j.1432-2277.2006.00356.x
https://doi.org/10.1111/j.1432-2277.2006.00356.x
Autor:
Nour Eddine El Mokhtari, Fokko J. van der Woude, Johannes Zschocke, Stefan Schreiber, Almut Nebel, Verena Peters, Michael Krawczak, Kate Wicks, Bart Janssen
Publikováno v:
Mechanisms of Ageing and Development. 127:817-820
Carnosine, a cytoprotective dipeptide found at very high concentrations in skeletal muscle, heart and brain, is cleaved in blood by serum carnosinase which is encoded by the CNDP1 gene. We recently found that homozygosity of a 5-leucine variant in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe2babe8b6f830156793b91b8b3b5733
https://doi.org/10.1016/j.mad.2006.08.002
https://doi.org/10.1016/j.mad.2006.08.002
Publikováno v:
American Journal of Kidney Diseases. 47:15-23
Background: Antineutrophil cytoplasmic antibodies (ANCAs) are considered by some investigators to be sensitive markers of disease activity and have been suggested to predict relapse and guide therapeutic decisions. Studies using serial ANCA monitorin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c00de78bf0f87efd9dcd8248913a1c1f
https://doi.org/10.1053/j.ajkd.2005.09.022
https://doi.org/10.1053/j.ajkd.2005.09.022
Autor:
Jihong Lin, Uwe Schubert, Hans-Peter Hammes, Günther Lochnit, Erwin Schleicher, Michael Brownlee, Alex Alt, Klaus T. Preissner, Fokko J. van der Woude, Jennifer Hoffmann, Triantaphyllos Chavakis
Publikováno v:
Thrombosis and Haemostasis. 95:689-695
SummaryHyperglycemia-induced mitochondrial overproduction of reactive oxygen species leads to the activation of different biochemical pathways involved in endothelial damage of the diabetic retina. Tenilsetam [(±)-3-(2-thienyl)-2-piperazinone] is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97abbd77d7ef87fbfe87b59e9e4c2b0a
https://doi.org/10.1160/th05-11-0725
https://doi.org/10.1160/th05-11-0725